PMID- 32400251
OWN - NLM
STAT- MEDLINE
DCOM- 20201021
LR  - 20201021
IS  - 1941-9260 (Electronic)
IS  - 0032-5481 (Linking)
VI  - 132
IP  - 6
DP  - 2020 Aug
TI  - Drug-eluting beads bronchial arterial chemoembolization as a neoadjuvant 
      treatment for squamous non-small cell lung cancer.
PG  - 568-571
LID - 10.1080/00325481.2020.1761711 [doi]
AB  - Introduction: The treatment for locally advanced squamous non-small cell lung 
      cancer is still challenging. Drug-eluting beads bronchial arterial 
      chemoembolization (DEB-BACE) is a novel drug delivery and embolization system for 
      lung cancer that has the potential to improve outcomes and reduce the incidence 
      of adverse events (AEs). It is very rare to administer DEB-BACE as neoadjuvant 
      therapy for lung cancer and achieve pathological complete response (pCR). Body: A 
      69-year-old male was hospitalized because of cough and hemoptysis caused by 
      locally advanced squamous non-small cell lung cancer. According to his choice, he 
      received DEB-BACE treatment without obvious AEs. After the DEB-BACE treatment, 
      the pulmonary lesion was controlled and lobectomy was performed. Postoperative 
      pathology showed pCR. The patient has recovered well. Conclusion: This was the 
      first case of DEB-BACE as a neoadjuvant therapy and achieved pCR for lung cancer. 
      DEB-BACE might be a new neoadjuvant therapy option for locally advanced non-small 
      cell lung cancer, especially for squamous cell cancer.
FAU - Yu, Guocan
AU  - Yu G
AUID- ORCID: 0000-0001-8570-8013
AD  - Department of Thoracic Surgery, The First Affiliated Hospital, School of 
      Medicine, Zhejiang University , Hangzhou, Zhejiang, China.
AD  - Department of Thoracic Surgery, Zhejiang Chinese Medicine and Western Medicine 
      Integrated Hospital , Hangzhou, Zhejiang, China.
FAU - Hu, Jian
AU  - Hu J
AUID- ORCID: 0000-0002-9494-9828
AD  - Department of Thoracic Surgery, The First Affiliated Hospital, School of 
      Medicine, Zhejiang University , Hangzhou, Zhejiang, China.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20200513
PL  - England
TA  - Postgrad Med
JT  - Postgraduate medicine
JID - 0401147
SB  - IM
MH  - Aged
MH  - *Bronchial Arteries
MH  - *Carcinoma, Non-Small-Cell Lung/pathology/physiopathology/therapy
MH  - Chemoembolization, Therapeutic/*methods
MH  - Drug Delivery Systems/methods
MH  - *Hemoptysis/etiology/therapy
MH  - Humans
MH  - *Lung/diagnostic imaging/surgery
MH  - *Lung Neoplasms/pathology/physiopathology/therapy
MH  - Male
MH  - Neoadjuvant Therapy/methods
MH  - Pneumonectomy/methods
MH  - Preoperative Care/methods
MH  - Tomography, X-Ray Computed/methods
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Drug-eluting beads
OT  - NSCLC
OT  - bronchial arterial chemoembolization
OT  - neoadjuvant treatment
OT  - pathological complete response
EDAT- 2020/05/14 06:00
MHDA- 2020/10/22 06:00
CRDT- 2020/05/14 06:00
PHST- 2020/05/14 06:00 [pubmed]
PHST- 2020/10/22 06:00 [medline]
PHST- 2020/05/14 06:00 [entrez]
AID - 10.1080/00325481.2020.1761711 [doi]
PST - ppublish
SO  - Postgrad Med. 2020 Aug;132(6):568-571. doi: 10.1080/00325481.2020.1761711. Epub 
      2020 May 13.