PMID- 32401473
OWN - NLM
STAT- MEDLINE
DCOM- 20210917
LR  - 20210917
IS  - 1827-1839 (Electronic)
IS  - 0392-9590 (Linking)
VI  - 39
IP  - 5
DP  - 2020 Oct
TI  - High-pressure, non compliant balloon angioplasty for long and calcified 
      infrapopliteal and inframalleolar lesions is feasible.
PG  - 390-397
LID - 10.23736/S0392-9590.20.04375-8 [doi]
AB  - BACKGROUND: To evaluate the safety, feasibility and effectiveness of 
      high-pressure, noncompliant balloon angioplasty in the management of long 
      infrapopliteal calcified lesions. METHODS: Consecutive patients, presenting with 
      chronic limb-threatening ischemia (CLTI) and long (>100 mm) calcified 
      infrapopliteal lesions who were treated with a high pressure, noncompliant 
      balloon (JADE, OrbusNeich, Hong Kong) between January 2016 and July 2016 were 
      retrospectively analyzed. Angioplasty was performed by inflating the balloon to a 
      pressure of 22 to 24 atm for 90 seconds. Primary outcome was technical success. 
      Secondary outcomes were procedure-related complications, limb salvage, 
      amputation-free survival (AFS), wound healing, overall survival, freedom from 
      clinically driven target lesion reintervention (CD-TLR), and resolution of CLTI 
      at 2 and 3 years. RESULTS: Overall, 23 lesions in 21 limbs of 20 patients were 
      treated. All patients had tissue loss (Rutherford 5 or 6). The mean lesion length 
      was 374.8 mm. Of all lesions, 56.5% were occlusions, 91.3% were classified as 
      TransAtlantic Inter-Society Consensus (TASC) C and D lesions, and 78.3% had 
      severe calcification classification. Of all lesions, 52.2% extended into the 
      below-the-ankle arteries. Technical success was achieved in 22 lesions (95.7%). 
      There were no procedure-related complications. No bailout stenting was required. 
      At 2 and 3 years, limb salvage was 84.7% and 78.7%, AFS was 71.4% and 56.1%, 
      wound healing was 81.0% and 85.7%, overall survival was 75.0% and 64.3% and 
      freedom from CD-TLR was 77.6% and 63.5%, respectively. Resolution of CLTI without 
      TLR was 81.0% at 2 and 3 years. CONCLUSIONS: This study is the first to analyze 
      safety and feasibility of a high-pressure, noncompliant balloon for long, 
      calcified infrapopliteal and inframalleolar lesions.
FAU - Huizing, Eline
AU  - Huizing E
AD  - Department of Surgery, Northwest Clinics, Alkmaar, the Netherlands - 
      e.huizing@nwz.nl.
FAU - Kum, Steven
AU  - Kum S
AD  - Vascular Service, Department of Surgery, Changi General Hospital, Singapore, 
      Singapore.
FAU - Adams, George
AU  - Adams G
AD  - Rex Healthcare, Raleigh, NC, USA.
FAU - Ferraresi, Roberto
AU  - Ferraresi R
AD  - Peripheral Interventional Unit, Humanitas Gavazzeni, Bergamo, Italy.
FAU - De Vries, Jean-Paul P M
AU  - De Vries JPM
AD  - Division of Vascular Surgery, Department of Surgery, University Medical Center 
      Groningen, Groningen, the Netherlands.
FAU - Unlu, Cagdas
AU  - Unlu C
AD  - Department of Surgery, Northwest Clinics, Alkmaar, the Netherlands.
LA  - eng
PT  - Journal Article
DEP - 20200513
PL  - Italy
TA  - Int Angiol
JT  - International angiology : a journal of the International Union of Angiology
JID - 8402693
SB  - IM
MH  - *Angioplasty, Balloon/adverse effects
MH  - Humans
MH  - Ischemia
MH  - Limb Salvage
MH  - *Peripheral Arterial Disease/diagnostic imaging/therapy
MH  - Popliteal Artery/diagnostic imaging
MH  - Retrospective Studies
MH  - Treatment Outcome
MH  - Vascular Patency
EDAT- 2020/05/14 06:00
MHDA- 2021/09/18 06:00
CRDT- 2020/05/14 06:00
PHST- 2020/05/14 06:00 [pubmed]
PHST- 2021/09/18 06:00 [medline]
PHST- 2020/05/14 06:00 [entrez]
AID - S0392-9590.20.04375-8 [pii]
AID - 10.23736/S0392-9590.20.04375-8 [doi]
PST - ppublish
SO  - Int Angiol. 2020 Oct;39(5):390-397. doi: 10.23736/S0392-9590.20.04375-8. Epub 
      2020 May 13.