PMID- 32403356 OWN - NLM STAT- MEDLINE DCOM- 20201111 LR - 20201111 IS - 1660-4601 (Electronic) IS - 1661-7827 (Print) IS - 1660-4601 (Linking) VI - 17 IP - 9 DP - 2020 May 11 TI - Evaluating the Investment Projects of Spinal Medical Device Firms Using the Real Option and DANP-mV Based MCDM Methods. LID - 10.3390/ijerph17093335 [doi] LID - 3335 AB - In an era of global aging, spinal and other joint degeneration issues have become a major problem for many elders. Bone-related operations have become the largest percentage of surgeries, accounting for 40% of the top 10 operations in the United States. Further, these spine-related operations are now ranked second among all bone-related operations. Due to this enormous and daily increasing market demand, more and more firms have started to pay closer attention to related medical devices and products. The global venture capitalists (VCs) have also started to follow the mega trend and will continue to invest heavily in this industry. Although most VCs recognize that investing in firms that produce innovative spinal products or devices is a must, very few practical managers or research scholars have defined the appropriate evaluation methods for these firms to use. The traditional net present value (NPV) method, which does not consider operation flexibility and changes in strategy, is far from the reality. The real option method can reveal the vagueness and flexibilities of the values being embedded in the investment projects at spinal medical device firms. However, the real option method is strictly quantitative. Usually, the evaluation aspects contain qualitative factors or local criteria which are hard to quantify in monetary terms. Thus, the adoption of multiple criteria decision making (MCDM) methods that can manipulate both quantitative and qualitative factors will be very helpful in evaluating and selecting investment cases like the spinal medical device firms, where both quantitative and qualitative factors should be considered. An analytical framework that consists of hybrid MCDM methods and the real option method will thus be very useful to evaluate the newly established firms producing spinal medical devices. Therefore, the authors propose a real option valuation as well as the Decision-Making Trial and Evaluation Laboratory (DEMATEL) based analytic network process (DANP) and the modified VIsekriterijumsko KOmpromisno Rangiranje (VIKOR) method (DANP-mV) based MCDM framework for evaluating the investment projects offered by these firms of spinal medical devices. An empirical study based on three newly established spinal medical device companies specializing in vertebral compression fracture (VCF) surgical devices was used to demonstrate the feasibility of the proposed analytical framework. Sensitivity analysis is performed to determine the influence of modeling parameters on ranking results of alternatives. This analytical framework can thus serve as a tool for VCs to use to determine the value of a potential candidate for investment. The proposed method can also serve as an effective and efficient tool for investment projects in other fields. FAU - Huang, Chi-Yo AU - Huang CY AD - Department of Industrial Education, National Taiwan Normal University, Taipei 106, Taiwan. FAU - Hsieh, Hong-Ling AU - Hsieh HL AD - Department of Industrial Education, National Taiwan Normal University, Taipei 106, Taiwan. FAU - Chen, Hueiling AU - Chen H AD - Graduate Institute of Management, National Taiwan Normal University, Taipei 106, Taiwan. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20200511 PL - Switzerland TA - Int J Environ Res Public Health JT - International journal of environmental research and public health JID - 101238455 SB - IM MH - Empirical Research MH - Equipment and Supplies/*economics MH - Fractures, Compression/*surgery MH - Humans MH - Investments MH - Manufacturing Industry/*trends MH - Research Design MH - Spinal Fractures/*surgery PMC - PMC7246546 OTO - NOTNLM OT - biotechnology OT - multiple criteria decision making (MCDM) OT - real option analysis OT - spinal device OT - venture capitalists (VCs) COIS- The authors declare no conflicts of interests. EDAT- 2020/05/15 06:00 MHDA- 2020/11/12 06:00 PMCR- 2020/05/01 CRDT- 2020/05/15 06:00 PHST- 2020/04/05 00:00 [received] PHST- 2020/05/04 00:00 [revised] PHST- 2020/05/05 00:00 [accepted] PHST- 2020/05/15 06:00 [entrez] PHST- 2020/05/15 06:00 [pubmed] PHST- 2020/11/12 06:00 [medline] PHST- 2020/05/01 00:00 [pmc-release] AID - ijerph17093335 [pii] AID - ijerph-17-03335 [pii] AID - 10.3390/ijerph17093335 [doi] PST - epublish SO - Int J Environ Res Public Health. 2020 May 11;17(9):3335. doi: 10.3390/ijerph17093335.