PMID- 32410802
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 1000-9604 (Print)
IS  - 1993-0631 (Electronic)
IS  - 1000-9604 (Linking)
VI  - 32
IP  - 2
DP  - 2020 Apr
TI  - Oncometabolic surgery: Emergence and legitimacy for investigation.
PG  - 252-262
LID - 10.21147/j.issn.1000-9604.2020.02.12 [doi]
AB  - Studies on morbid obesity have shown remarkable improvement of diabetes in 
      patients who have undergone bariatric operations. It was subsequently shown that 
      these operations induce diabetes remission independent of the resultant weight 
      loss; as a result, surgeons began to investigate whether operations for gastric 
      cancer (GC) could have the same beneficial effect on diabetes as bariatric 
      operations. It was then shown in multiple reports that followed that certain 
      operations for GC were able to improve or even cure type 2 diabetes mellitus 
      (T2DM) in GC patients. This finding gave rise to the concept of "oncometabolic 
      surgery", in which a patient diagnosed with both GC and T2DM undergo a single 
      operation with the purpose of treating both diseases. With the increasing 
      incidence of T2DM, oncometabolic surgery has the potential to improve the quality 
      of life and even extend survival of many GC patients. However, because the GC 
      patient population and the bariatric patient population are wildly different and 
      because different GC operations have different properties, the effect of 
      oncometabolic surgery must be carefully assessed and engineered in order to 
      maximize benefit and avoid harm. This manuscript aims to summarize the findings 
      made so far in the field of oncometabolic surgery and to provide an outlook 
      regarding the possibility of oncometabolic surgery being incorporated into 
      standard clinical practice.
CI  - Copyright (c) 2020 Chinese Journal of Cancer Research. All rights reserved.
FAU - Kim, Won Jun
AU  - Kim WJ
AD  - Korea University College of Medicine, Seoul 136-701, Republic of Korea.
FAU - Kwon, Yeongkeun
AU  - Kwon Y
AD  - Division of Foregut Surgery, Korea University College of Medicine, Seoul 136-701, 
      Republic of Korea.
FAU - Lee, Chang Min
AU  - Lee CM
AD  - Division of Foregut Surgery, Korea University College of Medicine, Seoul 136-701, 
      Republic of Korea.
FAU - Lim, Seung Hyun
AU  - Lim SH
AD  - Division of Foregut Surgery, Korea University College of Medicine, Seoul 136-701, 
      Republic of Korea.
FAU - Li, Yong
AU  - Li Y
AD  - Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong 
      Academy of Medical Sciences, Guangzhou 510080, China.
FAU - Wang, Junjiang
AU  - Wang J
AD  - Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong 
      Academy of Medical Sciences, Guangzhou 510080, China.
FAU - Hu, Weixian
AU  - Hu W
AD  - Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong 
      Academy of Medical Sciences, Guangzhou 510080, China.
FAU - Zheng, Jiabin
AU  - Zheng J
AD  - Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong 
      Academy of Medical Sciences, Guangzhou 510080, China.
FAU - Zhao, Gang
AU  - Zhao G
AD  - Department of Gastrointestinal Surgery, Shanghai Jiao Tong University School of 
      Medicine, Renji Hospital, Shanghai 200025, China.
FAU - Zhu, Chunchao
AU  - Zhu C
AD  - Department of Gastrointestinal Surgery, Shanghai Jiao Tong University School of 
      Medicine, Renji Hospital, Shanghai 200025, China.
FAU - Wang, Wei
AU  - Wang W
AD  - Department of Gastrointestinal Surgery, Guangdong Provincial Hospital of Chinese 
      Medicine, Guangzhou 510120, China.
FAU - Xiong, Wenjun
AU  - Xiong W
AD  - Department of Gastrointestinal Surgery, Guangdong Provincial Hospital of Chinese 
      Medicine, Guangzhou 510120, China.
FAU - Wang, Quan
AU  - Wang Q
AD  - Department of Gastrointestinal Surgery, The First Bethune Hospital of Jilin 
      University, Changchun 130021, China.
FAU - Xia, Mingjie
AU  - Xia M
AD  - Department of Gastrointestinal Surgery, The First Bethune Hospital of Jilin 
      University, Changchun 130021, China.
FAU - Park, Sungsoo
AU  - Park S
AD  - Division of Foregut Surgery, Korea University College of Medicine, Seoul 136-701, 
      Republic of Korea.
LA  - eng
PT  - Journal Article
PL  - China
TA  - Chin J Cancer Res
JT  - Chinese journal of cancer research = Chung-kuo yen cheng yen chiu
JID - 9315242
PMC - PMC7219104
OTO - NOTNLM
OT  - Stomach neoplasms
OT  - bariatric surgery
OT  - diabetes mellitus
OT  - gastric bypass
OT  - metabolic syndrome
EDAT- 2020/05/16 06:00
MHDA- 2020/05/16 06:01
PMCR- 2020/04/01
CRDT- 2020/05/16 06:00
PHST- 2020/05/16 06:00 [entrez]
PHST- 2020/05/16 06:00 [pubmed]
PHST- 2020/05/16 06:01 [medline]
PHST- 2020/04/01 00:00 [pmc-release]
AID - cjcr-32-2-252 [pii]
AID - 10.21147/j.issn.1000-9604.2020.02.12 [doi]
PST - ppublish
SO  - Chin J Cancer Res. 2020 Apr;32(2):252-262. doi: 
      10.21147/j.issn.1000-9604.2020.02.12.