PMID- 32412978
OWN - NLM
STAT- MEDLINE
DCOM- 20210806
LR  - 20210806
IS  - 1473-6519 (Electronic)
IS  - 1363-1950 (Linking)
VI  - 23
IP  - 4
DP  - 2020 Jul
TI  - Preoperative carbohydrates: what is new?
PG  - 262-270
LID - 10.1097/MCO.0000000000000661 [doi]
AB  - PURPOSE OF REVIEW: The aim of this review is to give an overview of recently 
      published articles covering preoperative carbohydrate loading in surgical 
      patients. RECENT FINDINGS: Between January 1, 2017, and December 31, 2019, 26 
      publications addressing the effect of carbohydrate load were retrieved through a 
      systematic search. Seventeen were randomized clinical trials, three prospective 
      observational studies and six retrospective series with case-control comparison. 
      Most of the studies were underpowered, addressed surrogate endpoints, and 
      variability among dose and timing of carbohydrate (CHO) treatment was high. The 
      most recent literature endorses preoperative carbohydrate loading up to 2 h 
      before operations as a safe treatment. The new evidence confirm that this 
      strategy is effective in reducing perioperative insulin resistance and the 
      proportion of hyperglycemia episodes, and improving patient well-being and 
      comfort but without affecting surgery-related morbidity. SUMMARY: Further 
      properly designed randomized clinical trials, addressing more clinically relevant 
      endpoints such as length of hospitalization and morbidity rate, are warrant.
FAU - Gianotti, Luca
AU  - Gianotti L
AD  - School of Medicine and Surgery, Milano - Bicocca University.
AD  - Department of Surgery, San Gerardo Hospital, Monza, Italy.
FAU - Sandini, Marta
AU  - Sandini M
AD  - School of Medicine and Surgery, Milano - Bicocca University.
AD  - Department of Surgery, San Gerardo Hospital, Monza, Italy.
AD  - Department of General, Visceral and Transplantation Surgery, University of 
      Heidelberg, Heidelberg, Germany.
FAU - Hackert, Thilo
AU  - Hackert T
AD  - Department of General, Visceral and Transplantation Surgery, University of 
      Heidelberg, Heidelberg, Germany.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Curr Opin Clin Nutr Metab Care
JT  - Current opinion in clinical nutrition and metabolic care
JID - 9804399
RN  - 0 (Biomarkers)
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
SB  - IM
MH  - Biomarkers/blood
MH  - Blood Glucose/*metabolism
MH  - Diet, Carbohydrate Loading/*methods
MH  - Dietary Carbohydrates/*administration & dosage
MH  - Humans
MH  - Hyperglycemia/prevention & control
MH  - Insulin Resistance
MH  - Observational Studies as Topic
MH  - Postoperative Complications/*prevention & control
MH  - Preoperative Care/*methods
MH  - Prospective Studies
MH  - Randomized Controlled Trials as Topic
MH  - Retrospective Studies
EDAT- 2020/05/16 06:00
MHDA- 2021/08/07 06:00
CRDT- 2020/05/16 06:00
PHST- 2020/05/16 06:00 [pubmed]
PHST- 2021/08/07 06:00 [medline]
PHST- 2020/05/16 06:00 [entrez]
AID - 00075197-202007000-00008 [pii]
AID - 10.1097/MCO.0000000000000661 [doi]
PST - ppublish
SO  - Curr Opin Clin Nutr Metab Care. 2020 Jul;23(4):262-270. doi: 
      10.1097/MCO.0000000000000661.