PMID- 32417508 OWN - NLM STAT- MEDLINE DCOM- 20200709 LR - 20200709 IS - 1879-1298 (Electronic) IS - 0045-6535 (Linking) VI - 255 DP - 2020 Sep TI - Novel brominated flame retardants - A review of their occurrence in indoor air, dust, consumer goods and food. PG - 126816 LID - S0045-6535(20)31009-2 [pii] LID - 10.1016/j.chemosphere.2020.126816 [doi] AB - This critical review summarizes the occurrence of 63 novel brominated flame retardants (NBFRs) in indoor air, dust, consumer goods and food. It includes their EU registration and (potential) risks. The increasing application of NBFRs calls for more research on their occurrence, environmental fate and toxicity. This review reports which NBFRs are actually being studied, which are detected and which are of most concern. It also connects data from the European Chemical Association on NBFRs with other scientific information. Large knowledge gaps emerged for 28 (out of 63) NBFRs, which were not included in any monitoring programs or other studies. This also indicates the need for optimized analytical methods including all NBFRs. Further research on indoor environments, emission sources and potential leaching is also necessary. High concentrations of 2-ethylhexyl 2,3,4,5-tetrabromobenzoate (EH-TBB), bis(2-ethylhexyl)tetrabromophthalate (BEH-TEBP), decabromodiphenyl ethane (DBDPE) and 1,2-bis(2,4,6-tribromophenoxy)ethane (BTBPE) were often reported. The detection of hexabromobenzene (HBB), pentabromotoluene (PBT), 1,4-dimethyltetrabromobenzene (TBX), 4-(1,2-dibromoethyl)-1,2-dibromocyclohexane (DBE-DBCH) and tetrabromobisphenol A bis(2,3-dibromopropyl) ether (TBBPA-BDBPE) also raises concern. CI - Copyright (c) 2020 The Authors. Published by Elsevier Ltd.. All rights reserved. FAU - Zuiderveen, Emma A R AU - Zuiderveen EAR AD - Department Environment and Health, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081, HV, Amsterdam, the Netherlands. Electronic address: e.zuiderveen@science.ru.nl. FAU - Slootweg, J Chris AU - Slootweg JC AD - Van 't Hoff Institute for Molecular Sciences, University of Amsterdam, PO Box 94157, 1090, GD, Amsterdam, the Netherlands. FAU - de Boer, Jacob AU - de Boer J AD - Department Environment and Health, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081, HV, Amsterdam, the Netherlands. LA - eng PT - Journal Article PT - Review DEP - 20200422 PL - England TA - Chemosphere JT - Chemosphere JID - 0320657 RN - 0 (Bromobenzenes) RN - 0 (Dust) RN - 0 (Flame Retardants) RN - 0 (Halogenated Diphenyl Ethers) RN - 0 (Polybrominated Biphenyls) RN - 0 (decabromodiphenyl ethane) RN - FQI02RFC3A (tetrabromobisphenol A) RN - T01859XWIR (hexabromobenzene) SB - IM MH - Air Pollution, Indoor/analysis/*statistics & numerical data MH - Bromobenzenes MH - Dust/analysis MH - *Environmental Monitoring MH - Flame Retardants/*analysis MH - Halogenated Diphenyl Ethers/analysis MH - Halogenation MH - Polybrominated Biphenyls COIS- Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2020/05/18 06:00 MHDA- 2020/07/10 06:00 CRDT- 2020/05/18 06:00 PHST- 2020/01/26 00:00 [received] PHST- 2020/03/30 00:00 [revised] PHST- 2020/04/13 00:00 [accepted] PHST- 2020/05/18 06:00 [pubmed] PHST- 2020/07/10 06:00 [medline] PHST- 2020/05/18 06:00 [entrez] AID - S0045-6535(20)31009-2 [pii] AID - 10.1016/j.chemosphere.2020.126816 [doi] PST - ppublish SO - Chemosphere. 2020 Sep;255:126816. doi: 10.1016/j.chemosphere.2020.126816. Epub 2020 Apr 22.