PMID- 32419596 OWN - NLM STAT- MEDLINE DCOM- 20201102 LR - 20221207 IS - 1545-1550 (Electronic) IS - 1526-6028 (Linking) VI - 27 IP - 4 DP - 2020 Aug TI - New Innovations and Devices in the Management of Chronic Limb-Threatening Ischemia. PG - 524-539 LID - 10.1177/1526602820921555 [doi] AB - As the number of patients afflicted by chronic limb-threatening ischemia (CLTI) continues to grow, new solutions are necessary to provide effective, durable treatment options that will lead to improved outcomes. The diagnosis of CLTI remains mostly clinical, and endovascular revascularization remains mostly balloon-based. Multiple innovative techniques and technologies are in development or in early usage that may provide new solutions. This review categorizes areas of advancement, highlights recent developments in the management of CLTI and looks forward to novel devices that are currently under investigation. FAU - Kim, Tanner I AU - Kim TI AUID- ORCID: 0000-0002-7524-2894 AD - Division of Vascular Surgery, Department of Surgery, Yale School of Medicine, New Haven, CT, USA. FAU - Schneider, Peter A AU - Schneider PA AD - Division of Vascular and Endovascular Surgery, University of California at San Francisco School of Medicine, San Francisco, CA, USA. LA - eng PT - Journal Article PT - Review DEP - 20200518 PL - United States TA - J Endovasc Ther JT - Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists JID - 100896915 RN - 0 (Coated Materials, Biocompatible) SB - IM MH - Absorbable Implants/trends MH - Amputation, Surgical/trends MH - Chronic Disease MH - Coated Materials, Biocompatible MH - Diffusion of Innovation MH - Drug-Eluting Stents/trends MH - Endovascular Procedures/adverse effects/instrumentation/*trends MH - Humans MH - Ischemia/diagnostic imaging/physiopathology/*therapy MH - Limb Salvage/trends MH - Peripheral Arterial Disease/diagnostic imaging/physiopathology/*therapy MH - Prosthesis Design/trends MH - Risk Factors MH - Treatment Outcome MH - Vascular Access Devices/trends OTO - NOTNLM OT - angioplasty OT - below-the-knee arteries OT - bioabsorbable scaffolds OT - chronic limb-threatening ischemia OT - dissections OT - drug delivery OT - drug-coated balloon OT - drug-eluting stent OT - endovascular therapy OT - femoropopliteal segment OT - intravascular lithoplasty OT - percutaneous deep venous arterialization OT - retrograde pedal access OT - serrated balloon OT - stent EDAT- 2020/05/19 06:00 MHDA- 2020/11/03 06:00 CRDT- 2020/05/19 06:00 PHST- 2020/05/19 06:00 [pubmed] PHST- 2020/11/03 06:00 [medline] PHST- 2020/05/19 06:00 [entrez] AID - 10.1177/1526602820921555 [doi] PST - ppublish SO - J Endovasc Ther. 2020 Aug;27(4):524-539. doi: 10.1177/1526602820921555. Epub 2020 May 18.