PMID- 32420158
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220414
IS  - 2223-4691 (Print)
IS  - 2223-4691 (Electronic)
IS  - 2223-4683 (Linking)
VI  - 9
IP  - 2
DP  - 2020 Apr
TI  - Minimally invasive, sutureless, adolescent male circumcision with topical 
      anesthetic: a field trial of Unicirc, a single-use surgical instrument.
PG  - 516-522
LID - 10.21037/tau.2019.12.16 [doi]
AB  - BACKGROUND: Circumcision has been shown to reduce the rate of HIV transmission in 
      Africa. It is most cost effective if performed in younger men. Surgical assist 
      devices can increase the efficiency and potentially reduce the cost of performing 
      circumcisions. METHODS: We used the Unicirc disposable instrument to perform 
      circumcisions in an outpatient primary care clinic. The trial was non-blinded. 
      Circumcisions were performed under topical anaesthetic and the wound was sealed 
      with cyanoacrylate tissue adhesive. The primary outcome was intraoperative 
      duration; secondary outcomes were intraoperative and postoperative pain; adverse 
      events (AEs); time to healing and patient satisfaction; and, cosmetic result. 
      RESULTS: A total of 82 adolescent boys (aged 10-15 years) were circumcised. The 
      median intraoperative time was 10 minutes and the median blood loss was 1 mL. All 
      wounds were healed by 4 weeks and cosmetic results were excellent. There were no 
      AEs. CONCLUSIONS: Adolescent circumcision with Unicirc under topical anesthetic 
      and wound sealing with cyanoacrylate tissue adhesive is safe, rapid, and heals by 
      primary intention with excellent cosmetic results. It is cost effective and can 
      be used for large scale programs.
CI  - 2020 Translational Andrology and Urology. All rights reserved.
FAU - Millard, Peter S
AU  - Millard PS
AD  - Department of Family Medicine, University of New England, Biddeford, Maine, USA.
FAU - Goldstuck, Norman
AU  - Goldstuck N
AD  - Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University 
      of Stellenbosch, Cape Town, South Africa.
LA  - eng
PT  - Journal Article
PL  - China
TA  - Transl Androl Urol
JT  - Translational andrology and urology
JID - 101581119
PMC - PMC7214996
OTO - NOTNLM
OT  - Circumcision
OT  - HIV prevention
OT  - disposable instrument
OT  - minimally invasive
OT  - surgical instrument
OT  - tissue adhesive
OT  - topical anaesthetic
COIS- Conflicts of Interest: All authors have completed the ICMJE uniform disclosure 
      form (available at http://dx.doi.org/10.21037/tau.2019.12.16). The authors have 
      no conflicts of interest to declare.
EDAT- 2020/05/19 06:00
MHDA- 2020/05/19 06:01
PMCR- 2020/04/01
CRDT- 2020/05/19 06:00
PHST- 2020/05/19 06:00 [entrez]
PHST- 2020/05/19 06:00 [pubmed]
PHST- 2020/05/19 06:01 [medline]
PHST- 2020/04/01 00:00 [pmc-release]
AID - tau-09-02-516 [pii]
AID - 10.21037/tau.2019.12.16 [doi]
PST - ppublish
SO  - Transl Androl Urol. 2020 Apr;9(2):516-522. doi: 10.21037/tau.2019.12.16.