PMID- 32431986
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 12
IP  - 4
DP  - 2020 Apr 17
TI  - Serous Microcystic Cystadenocarcinoma of the Pancreas with Synchronous Liver 
      Metastases: Clinical Characteristics and Management.
PG  - e7707
LID - 10.7759/cureus.7707 [doi]
LID - e7707
AB  - Serous cystadenocarcinoma of the pancreas is a rare but well-established entity. 
      The origin and evolution of this disorder remain unclear, but even metastatic 
      cases have an excellent prognosis. These tumors are very similar to benign serous 
      cystic neoplasms (SCNs) of the pancreas, except that they tend to be larger, are 
      locally invasive, and present distant metastasis. The most frequent local 
      invasion is adjacent vessels, spleen, stomach, and duodenum. The most common site 
      of distant metastasis is the liver. Diagnosis via imaging as well as pathology 
      examination may be misguided due to atypical characteristics of the tumor. In 
      fact, in some, the diagnosis of malignancy was established only after metastases 
      were detected. We present a 60-year-old female patient with malignant serous 
      microcystic cystadenocarcinoma of the pancreas and liver metastasis that was 
      initially misdiagnosed as a metastatic renal cell carcinoma. The patient 
      underwent tumor resection and liver metastasectomy and she is currently doing 
      well after three years of follow-up, with no tumor recurrence or new metastatic 
      liver nodules based on imaging findings.
CI  - Copyright (c) 2020, Massaras et al.
FAU - Massaras, Dimitrios
AU  - Massaras D
AD  - Surgery, Aretaieio Hospital, National and Kapodistrian University of Athens 
      School of Medicine, Athens, GRC.
FAU - Pantiora, Eirini V
AU  - Pantiora EV
AD  - Surgery, Aretaieio Hospital, National and Kapodistrian University of Athens 
      School of Medicine, Athens, GRC.
FAU - Koutalas, John
AU  - Koutalas J
AD  - Anesthesiology, Aretaieio Hospital, National and Kapodistrian University of 
      Athens School of Medicine, Athens, GRC.
FAU - Primetis, Elias C
AU  - Primetis EC
AD  - Radiology, Tiefenau Hospital, Bern, CHE.
FAU - Fragulidis, Georgios P
AU  - Fragulidis GP
AD  - 2nd Department of Surgery, "Aretaeio" Hospital, National and Kapodistrian 
      University of Athens School of Medicine, Athens, GRC.
LA  - eng
PT  - Case Reports
DEP - 20200417
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC7233488
OTO - NOTNLM
OT  - cystadenocarcinoma
OT  - digestive surgery
OT  - indications for surgery
OT  - liver metastasis
OT  - microcystic
OT  - pancreas
OT  - serous cystic neoplasm
OT  - sunitinib
COIS- The authors have declared that no competing interests exist.
EDAT- 2020/05/21 06:00
MHDA- 2020/05/21 06:01
PMCR- 2020/04/17
CRDT- 2020/05/21 06:00
PHST- 2020/05/21 06:00 [entrez]
PHST- 2020/05/21 06:00 [pubmed]
PHST- 2020/05/21 06:01 [medline]
PHST- 2020/04/17 00:00 [pmc-release]
AID - 10.7759/cureus.7707 [doi]
PST - epublish
SO  - Cureus. 2020 Apr 17;12(4):e7707. doi: 10.7759/cureus.7707.