PMID- 32438483
OWN - NLM
STAT- MEDLINE
DCOM- 20210426
LR  - 20210426
IS  - 1879-0844 (Electronic)
IS  - 1388-9842 (Linking)
VI  - 22
IP  - 6
DP  - 2020 Jun
TI  - Telemonitoring versus standard care in heart failure: a randomised multicentre 
      trial.
PG  - 985-994
LID - 10.1002/ejhf.1906 [doi]
AB  - AIMS: The aim was to assess the effect of a telemonitoring programme vs. standard 
      care (SC) in preventing all-cause deaths or unplanned hospitalisations in heart 
      failure (HF) at 18 months. METHODS AND RESULTS: OSICAT was a randomised, 
      multicentre, open-label French study in 937 patients hospitalised for acute HF 
      </=12 months before inclusion. Patients were randomised to telemonitoring (daily 
      body weight measurement, daily recording of HF symptoms, and personalised 
      education) (n = 482) or to SC (n = 455). Mean +/- standard deviation number of 
      events for the primary outcome was 1.30 +/- 1.85 for telemonitoring and 1.46 +/- 1.98 
      for SC [rate ratio 0.97, 95% confidence interval (CI) 0.77-1.23; P = 0.80]. In 
      New York Heart Association (NYHA) class III or IV HF, median time to all-cause 
      death or first unplanned hospitalisation was 82 days in the telemonitoring group 
      and 67 days in the SC group (P = 0.03). After adjustment for known predictive 
      factors, telemonitoring was associated with a 21% relative risk reduction in 
      first unplanned hospitalisation for HF [hazard ratio (HR) 0.79, 95% CI 0.62-0.99; 
      P = 0.044); the relative risk reduction was 29% in patients with NYHA class III 
      or IV HF (HR 0.71, 95% CI 0.53-0.95; P = 0.02), 38% in socially isolated patients 
      (HR 0.62, 95% CI 0.39-0.98; P = 0.043), and 37% in patients who were >/=70% 
      adherent to body weight measurement (HR 0.63, 95% CI 0.45-0.88; P = 0.006). 
      CONCLUSION: Telemonitoring did not result in a significantly lower rate of 
      all-cause deaths or unplanned hospitalisations in HF patients. The pre-specified 
      subgroup results suggest the telemonitoring approach improves clinical outcomes 
      in selected populations but need further confirmation.
CI  - (c) 2020 European Society of Cardiology.
FAU - Galinier, Michel
AU  - Galinier M
AD  - Cardiology, Toulouse Rangueil University Hospital (CHU), Toulouse, France.
AD  - UMR UT3 CNRS 5288 Evolutionary Medicine, Obesity and Heart Failure: Molecular and 
      Clinical Investigations, INI-CRCT F-CRIN, GREAT Networks, Toulouse, France.
AD  - Faculty of Medicine, University of Paul Sabatier-Toulouse III, Toulouse, France.
FAU - Roubille, Francois
AU  - Roubille F
AD  - PhyMedExp, Universite de Montpellier, INSERM, CNRS, Cardiology Department, 
      University Hospital of Montpellier, Montpellier, France.
FAU - Berdague, Philippe
AU  - Berdague P
AD  - Beziers Hospital Centre, Beziers, France.
AD  - MSP Beziers, Beziers, France.
FAU - Brierre, Gilles
AU  - Brierre G
AD  - Intercommunal Hospital Centre des Vallees de l'Ariege, Foix, France.
FAU - Cantie, Philippe
AU  - Cantie P
AD  - Intercommunal Hospital Centre Castres-Mazamet, Castres, France.
FAU - Dary, Patrick
AU  - Dary P
AD  - Private Practice, Saint Yrieix La Perche, France.
FAU - Ferradou, Jean-Marc
AU  - Ferradou JM
AD  - Cardiology Aftercare and Rehabilitation Centre, Beaumont de Lomagne, France.
FAU - Fondard, Olivier
AU  - Fondard O
AD  - Pasteur Clinic, Toulouse, France.
FAU - Labarre, Jean Philippe
AU  - Labarre JP
AD  - Pont de Chaume Clinic, Montauban, France.
FAU - Mansourati, Jacques
AU  - Mansourati J
AD  - CHRU Brest, Brest, France.
FAU - Picard, Francois
AU  - Picard F
AD  - Unite d'Insuffisance Cardiaque, Centre Hospitalier Universitaire de Bordeaux, 
      Bordeaux, France.
FAU - Ricci, Jean-Etienne
AU  - Ricci JE
AD  - University Hospital of Nimes, Nimes, France.
FAU - Salvat, Muriel
AU  - Salvat M
AD  - University Hospital of Grenoble, Grenoble, France.
FAU - Tartiere, Lamia
AU  - Tartiere L
AD  - Leon Berard Hospital, Hyeres, France.
FAU - Ruidavets, Jean-Bernard
AU  - Ruidavets JB
AD  - INSERM UMR - U1027, Toulouse, France.
FAU - Bongard, Vanina
AU  - Bongard V
AD  - USMR - CHU Toulouse, Toulouse, France.
FAU - Delval, Cecile
AU  - Delval C
AD  - Air Liquide Sante International, Loges en Josas, France.
FAU - Lancman, Guila
AU  - Lancman G
AD  - Air Liquide Sante International, Loges en Josas, France.
FAU - Pasche, Helene
AU  - Pasche H
AD  - Air Liquide Sante International, Loges en Josas, France.
FAU - Ramirez-Gil, Juan Fernando
AU  - Ramirez-Gil JF
AD  - Air Liquide Sante International, Loges en Josas, France.
FAU - Pathak, Atul
AU  - Pathak A
AD  - Department of Cardiovascular Medicine, Princess Grace Hospital, Monaco, Monaco.
CN  - OSICAT Investigators
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20200615
PL  - England
TA  - Eur J Heart Fail
JT  - European journal of heart failure
JID - 100887595
SB  - IM
CIN - Eur J Heart Fail. 2020 Jun;22(6):995-998. PMID: 32385954
MH  - Aged
MH  - Aged, 80 and over
MH  - Female
MH  - *Heart Failure/mortality/therapy
MH  - Hospitalization/statistics & numerical data
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Standard of Care
MH  - *Telemedicine
OTO - NOTNLM
OT  - Body weight
OT  - Heart failure
OT  - Hospitalisation
OT  - Patient education
OT  - Telemonitoring
EDAT- 2020/05/22 06:00
MHDA- 2021/04/27 06:00
CRDT- 2020/05/22 06:00
PHST- 2020/03/06 00:00 [received]
PHST- 2020/05/13 00:00 [revised]
PHST- 2020/05/19 00:00 [accepted]
PHST- 2020/05/22 06:00 [pubmed]
PHST- 2021/04/27 06:00 [medline]
PHST- 2020/05/22 06:00 [entrez]
AID - 10.1002/ejhf.1906 [doi]
PST - ppublish
SO  - Eur J Heart Fail. 2020 Jun;22(6):985-994. doi: 10.1002/ejhf.1906. Epub 2020 Jun 
      15.