PMID- 32460232
OWN - NLM
STAT- MEDLINE
DCOM- 20210621
LR  - 20210621
IS  - 1876-7753 (Electronic)
IS  - 1873-5061 (Linking)
VI  - 46
DP  - 2020 Jul
TI  - Generation of three induced pluripotent stem cell (iPSC) lines from a multiple 
      endocrine neoplasia type 1 (MEN1) patient and three iPSC lines from an unaffected 
      relative of the patient.
PG  - 101846
LID - S1873-5061(20)30147-1 [pii]
LID - 10.1016/j.scr.2020.101846 [doi]
AB  - We generated three disease-specific iPSC lines from a Multiple endocrine 
      neoplasia type 1 (MEN1) patient and three control iPSC lines from an unaffected 
      blood relative of the patient using unutilized lymphoblastoid B cell lines (LCLs) 
      as a cell resource. The expression of pluripotency markers, retaining of normal 
      karyotype of chromosome, absence of episomal vectors used for generating the 
      iPSCs and EBV used for generating LCLs, and the potential to differentiate into 
      three germ layers, were confirmed for each iPSC line. These iPSC lines can be 
      useful for construction of the disease models in vitro, and elucidation of the 
      disease mechanisms.
CI  - Copyright (c) 2020. Published by Elsevier B.V.
FAU - Yoshida, Satoru
AU  - Yoshida S
AD  - Department of Regenerative Medicine and Stem Cell Biology, Fujita Health 
      University School of Medicine, Toyoake, Japan.
FAU - Okura, Hanayuki
AU  - Okura H
AD  - Department of Regenerative Medicine Support Promotion Facility, Center for 
      Research Promotion and Support, Fujita Health University, Toyoake, Japan.
FAU - Suga, Hidetaka
AU  - Suga H
AD  - Department of Endocrinology and Diabetes, Nagoya University Graduate School of 
      Medicine, Nagoya, Japan.
FAU - Nishitomi, Tomohiko
AU  - Nishitomi T
AD  - Department of Regenerative Medicine and Stem Cell Biology, Fujita Health 
      University School of Medicine, Toyoake, Japan.
FAU - Sakurai, Akihiro
AU  - Sakurai A
AD  - Department of Medical Genetics and Genomics, Sapporo Medical University School of 
      Medicine, Sapporo, Japan.
FAU - Arima, Hiroshi
AU  - Arima H
AD  - Department of Endocrinology and Diabetes, Nagoya University Graduate School of 
      Medicine, Nagoya, Japan.
FAU - Matsuyama, Akifumi
AU  - Matsuyama A
AD  - Department of Regenerative Medicine and Stem Cell Biology, Fujita Health 
      University School of Medicine, Toyoake, Japan. Electronic address: 
      akifumi-matsuyama@umin.ac.jp.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20200516
PL  - England
TA  - Stem Cell Res
JT  - Stem cell research
JID - 101316957
SB  - IM
MH  - Cell Differentiation
MH  - Cell Line
MH  - Humans
MH  - *Induced Pluripotent Stem Cells
MH  - *Multiple Endocrine Neoplasia Type 1/genetics
MH  - Plasmids
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2020/05/28 06:00
MHDA- 2021/06/22 06:00
CRDT- 2020/05/28 06:00
PHST- 2020/02/18 00:00 [received]
PHST- 2020/04/20 00:00 [revised]
PHST- 2020/05/11 00:00 [accepted]
PHST- 2020/05/28 06:00 [pubmed]
PHST- 2021/06/22 06:00 [medline]
PHST- 2020/05/28 06:00 [entrez]
AID - S1873-5061(20)30147-1 [pii]
AID - 10.1016/j.scr.2020.101846 [doi]
PST - ppublish
SO  - Stem Cell Res. 2020 Jul;46:101846. doi: 10.1016/j.scr.2020.101846. Epub 2020 May 
      16.