PMID- 32461727
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 1349-0486 (Electronic)
IS  - 1346-7395 (Print)
IS  - 1346-7395 (Linking)
VI  - 57
IP  - 2
DP  - 2020 Apr 25
TI  - Optimal Dietary Levels of 1alpha-Hydroxycholecalciferol in Broiler Chickens from 1 to 
      42 Days of Age.
PG  - 124-130
LID - 10.2141/jpsa.0190013 [doi]
AB  - 1alpha-Hydroxycholecalciferol (1alpha-OH-D(3)) is an active vitamin D derivative. In this 
      study, three experiments were conducted to evaluate the optimal dietary levels of 
      1alpha-OH-D(3) in broiler chickens from 1 to 42 days of age. 1alpha-OH-D(3) levels used 
      were 0, 1.25, 2.5, 5, and 10 microg/kg in experiment 1, 0.625, 1.25, 2.5, 5, 7.5, and 
      10 microg/kg in experiment 2, and 2, 2.5, 3, 3.5, 4, 4.5, and 5 microg/kg in experiment 
      3. In experiment 1, the addition of 0 to 10 microg/kg of 1alpha-OH-D(3) quadratically 
      improved growth performance, tibia development, and mRNA expression levels of 
      nuclear vitamin D receptor (nVDR), membrane vitamin D receptor (mVDR), and type 
      IIb sodium-phosphate cotransporter (NaPi-IIb) in the duodenum of broiler chickens 
      from 1 to 12 days of age. Body weight gain (BWG), the weight and ash weight of 
      the tibia, and mRNA expression levels of mVDR and NaPi-IIb of broilers fed with 0 
      and 10 microg/kg of 1alpha-OH-D(3) were lower than those of birds fed with 2.5 microg/kg of 
      1alpha-OH-D(3). In experiment 2, 1alpha-OH-D(3) levels were quadratically related to BWG 
      and to weight and ash weight of the femur and the tibia of broiler chickens at 42 
      days of age. The highest values of growth performance and bone mineralization 
      were recorded in broilers fed with 2.5 to 5 microg/kg of 1alpha-OH-D(3). In experiment 3, 
      there was no difference observed in BWG and the weight and ash weight of the 
      femur and the tibia of the 42-day-old broilers fed with 2 to 5 microg/kg of 
      1alpha-OH-D(3). These data suggest that the optimal dietary levels of 1alpha-OH-D(3) were 
      2 to 5 microg/kg for broiler chickens from 1 to 42 days of age.
CI  - 2020, Japan Poultry Science Association.
FAU - Yang, Xue
AU  - Yang X
AD  - College of Animal Science and Veterinary Medicine, Henan Agricultural University, 
      Zhengzhou, Henan, China.
AD  - Department of Animal Science, College of Life Science, Shangqiu Normal 
      University, Shangqiu, Henan, China.
FAU - Zhang, Ning
AU  - Zhang N
AD  - College of Animal Science and Veterinary Medicine, Henan Agricultural University, 
      Zhengzhou, Henan, China.
AD  - Department of Animal Science, College of Life Science, Shangqiu Normal 
      University, Shangqiu, Henan, China.
FAU - Wang, Xiaona
AU  - Wang X
AD  - College of Animal Science and Veterinary Medicine, Henan Agricultural University, 
      Zhengzhou, Henan, China.
AD  - Department of Animal Science, College of Life Science, Shangqiu Normal 
      University, Shangqiu, Henan, China.
FAU - Qu, Hongxia
AU  - Qu H
AD  - Department of Animal Science, College of Life Science, Shangqiu Normal 
      University, Shangqiu, Henan, China.
FAU - Zhang, Jinliang
AU  - Zhang J
AD  - Department of Animal Science, College of Life Science, Shangqiu Normal 
      University, Shangqiu, Henan, China.
FAU - Yan, Yongfeng
AU  - Yan Y
AD  - Department of Animal Science, College of Life Science, Shangqiu Normal 
      University, Shangqiu, Henan, China.
FAU - Cheng, Yeonghsiang
AU  - Cheng Y
AD  - Department of Biotechnology and Animal Science, National Ilan University, Taiwan.
FAU - Han, Jincheng
AU  - Han J
AD  - Department of Animal Science, College of Life Science, Shangqiu Normal 
      University, Shangqiu, Henan, China.
LA  - eng
PT  - Journal Article
PL  - Japan
TA  - J Poult Sci
JT  - The journal of poultry science
JID - 101226346
PMC - PMC7248009
OTO - NOTNLM
OT  - 1alpha-hydroxycholecalciferol
OT  - bone
OT  - broiler chicken
OT  - growth
OT  - type IIb sodium-phosphate cotransporter
OT  - vitamin D receptor
EDAT- 2020/05/29 06:00
MHDA- 2020/05/29 06:01
PMCR- 2020/04/25
CRDT- 2020/05/29 06:00
PHST- 2020/05/29 06:00 [entrez]
PHST- 2020/05/29 06:00 [pubmed]
PHST- 2020/05/29 06:01 [medline]
PHST- 2020/04/25 00:00 [pmc-release]
AID - 10.2141/jpsa.0190013 [doi]
PST - ppublish
SO  - J Poult Sci. 2020 Apr 25;57(2):124-130. doi: 10.2141/jpsa.0190013.