PMID- 32461902
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 2214-2509 (Print)
IS  - 2214-2509 (Electronic)
IS  - 2214-2509 (Linking)
VI  - 21
DP  - 2020
TI  - Cytomegalovirus-associated esophageal stricture as a manifestation of the immune 
      reconstitution inflammatory syndrome.
PG  - e00795
LID - 10.1016/j.idcr.2020.e00795 [doi]
LID - e00795
AB  - Cytomegalovirus (CMV) esophagitis is well described in immunocompromised 
      individuals, however, esophageal stricture due to CMV is rare. CMV disease in the 
      setting of the immune reconstitution inflammatory syndrome (IRIS) usually takes 
      the form of an immune-recovery uveitis or retinitis. We describe a young female 
      patient with HIV who developed an esophageal stricture due to CMV within 6 months 
      of starting antiretroviral therapy (ART). The patient responded well to treatment 
      which involved 14 days of intravenous ganciclovir and esophageal dilatation. This 
      is the first description of a patient developing gastrointestinal cytomegalovirus 
      disease as a manifestation of IRIS.
CI  - (c) 2020 Published by Elsevier Ltd.
FAU - Mansfield, B S
AU  - Mansfield BS
AD  - Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, 
      Johannesburg, South Africa.
AD  - Department of Internal Medicine, Faculty of Health Sciences, University of the 
      Witwatersrand, Johannesburg, South Africa.
FAU - Savage-Reid, M J
AU  - Savage-Reid MJ
AD  - Division of Anatomical Pathology, National Health Laboratory Services, Chris Hani 
      Baragwanath Academic Hospital, Johannesburg, South Africa.
FAU - Moyo, J
AU  - Moyo J
AD  - Department of Surgery, Chris Hani Baragwanath Academic Hospital, Johannesburg, 
      South Africa.
FAU - Menezes, C N
AU  - Menezes CN
AD  - Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, 
      Johannesburg, South Africa.
AD  - Department of Internal Medicine, Faculty of Health Sciences, University of the 
      Witwatersrand, Johannesburg, South Africa.
LA  - eng
PT  - Case Reports
DEP - 20200511
PL  - Netherlands
TA  - IDCases
JT  - IDCases
JID - 101634540
PMC - PMC7242862
OTO - NOTNLM
OT  - Cytomegalovirus
OT  - Esophageal stricture
OT  - Immune reconstitution inflammatory syndrome
COIS- The authors declare no conflict of interest.
EDAT- 2020/05/29 06:00
MHDA- 2020/05/29 06:01
PMCR- 2020/05/11
CRDT- 2020/05/29 06:00
PHST- 2020/04/25 00:00 [received]
PHST- 2020/05/03 00:00 [revised]
PHST- 2020/05/03 00:00 [accepted]
PHST- 2020/05/29 06:00 [entrez]
PHST- 2020/05/29 06:00 [pubmed]
PHST- 2020/05/29 06:01 [medline]
PHST- 2020/05/11 00:00 [pmc-release]
AID - S2214-2509(20)30103-7 [pii]
AID - e00795 [pii]
AID - 10.1016/j.idcr.2020.e00795 [doi]
PST - epublish
SO  - IDCases. 2020 May 11;21:e00795. doi: 10.1016/j.idcr.2020.e00795. eCollection 
      2020.