PMID- 32462264 OWN - NLM STAT- MEDLINE DCOM- 20210818 LR - 20210818 IS - 1896-1851 (Electronic) IS - 1230-2821 (Linking) VI - 65 IP - 4 DP - 2020 Dec TI - Hematological and Biochemical Changes in Naturally Occurring Equine Piroplasmosis in Donkeys (Equus asinus) of Northwest of Iran. PG - 811-816 LID - 10.2478/s11686-020-00223-0 [doi] AB - PURPOSE: Equine piroplasmosis is a tick-borne protozoal disease affecting horses, mules, donkeys and zebras and can lead to severe economic losses in the equine industry. There is limited information on clinical pathologic changes of equine piroplasmosis in donkeys. This study aims to investigate the impacts of babesiosis on various hematological and biochemical properties in naturally infected donkeys with Theileria equi and Babesia caballi. METHODS: A total of 200 apparently healthy donkeys were randomly examined for the presence of equine piroplasmosis in blood samples. Of 200 samples, 11(5.5%) animals were positive for T. equi and 3(1.5%) of the samples were infected with B. caballi. 14 uninfected donkeys, were also selected as a control group. RESULTS: The results of the comparison showed that infected donkeys presented a significant elevation (P < 0.05) of total leukocyte count, number of lymphocyte, monocyte, neutrophil and eosinophil, while showed a significant decreased in (P < 0.05) hemoglobin concentration (Hb), packed cell volume (PCV), red blood cells (RBCs), mean corpuscular volume (MCV) and mean corpuscular hemoglobin concentration (MCHC). The infected donkeys had significantly higher levels of total protein and total bilirubin (P < 0.05), whereas the amount of albumin was significantly lower in comparison to healthy animals (P < 0.05). It is interesting to note that the amounts of urea, cholesterol, creatinine, triglyceride, LDL and HDL, CK, AST, LDH, GGT, and Malondialdehyde were significantly higher (P < 0.05) in infected donkeys. CONCLUSIONS: The current study describes laboratory findings in the affected donkeys which were good criteria for diagnosis and control of equine piroplasmosis in donkeys. FAU - Ahmadi Afshar, Neda AU - Ahmadi Afshar N AD - Faculty of Veterinary Medicine, Urmia University, Urmia, Iran. FAU - Malekifard, Farnaz AU - Malekifard F AUID- ORCID: 0000-0002-4809-3782 AD - Department of Pathobiology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran. f.malekifard@urmia.ac.ir. FAU - Asri Rezaei, Siamak AU - Asri Rezaei S AD - Department of Internal Diseases and Clinical Pathology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran. FAU - Tavassoli, Mousa AU - Tavassoli M AD - Department of Pathobiology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran. LA - eng PT - Journal Article DEP - 20200527 PL - Switzerland TA - Acta Parasitol JT - Acta parasitologica JID - 9301947 SB - IM MH - Animals MH - *Babesiosis/epidemiology MH - Cattle MH - Equidae MH - *Horse Diseases MH - Horses MH - Iran/epidemiology MH - *Theileria MH - *Theileriasis/epidemiology OTO - NOTNLM OT - Babesia caballi OT - Biochemical parameters OT - Donkey OT - Hematology OT - Theileria equi EDAT- 2020/05/29 06:00 MHDA- 2021/08/19 06:00 CRDT- 2020/05/29 06:00 PHST- 2020/01/26 00:00 [received] PHST- 2020/04/29 00:00 [accepted] PHST- 2020/05/29 06:00 [pubmed] PHST- 2021/08/19 06:00 [medline] PHST- 2020/05/29 06:00 [entrez] AID - 10.2478/s11686-020-00223-0 [pii] AID - 10.2478/s11686-020-00223-0 [doi] PST - ppublish SO - Acta Parasitol. 2020 Dec;65(4):811-816. doi: 10.2478/s11686-020-00223-0. Epub 2020 May 27.