PMID- 32464537
OWN - NLM
STAT- MEDLINE
DCOM- 20210407
LR  - 20210407
IS  - 1879-2219 (Electronic)
IS  - 0966-6362 (Linking)
VI  - 80
DP  - 2020 Jul
TI  - Responsiveness and minimal clinically important difference of the Mini-BESTest in 
      patients with Parkinson's disease.
PG  - 14-19
LID - S0966-6362(20)30154-5 [pii]
LID - 10.1016/j.gaitpost.2020.05.004 [doi]
AB  - BACKGROUND: Balance problems in Parkinson's Disease (PD) require appropriate 
      evaluation. While the Mini-BESTest is commonly used to assess dynamic balance, 
      some of its psychometric properties have not yet been addressed. RESEARCH 
      QUESTION: What is the responsiveness and the Minimal Clinically Important 
      Difference (MCID) of the Mini-BESTest in patients with PD? METHODS: One-hundred 
      forty-eight patients with PD underwent a treatment specific for balance skills 
      (1-h session, three times/week for four weeks). All patients were initially 
      evaluated with the Mini-BESTest and Activities-Specific Balance Confidence scale 
      5-levels (ABC-5L). Post-treatment, patients were assessed with the Mini-BESTest, 
      ABC-5L and Global Rating of Change (GRC, both patient- and 
      physiotherapist-rated). Responsiveness to treatment and MCID were calculated with 
      distribution and anchor-based methods: effect size, area under the curve (AUC) of 
      receiver operating characteristics (ROC), and correlations between evaluations 
      (change in score of Mini-BESTest, ABC-5L, GRC). Eleven a priori hypotheses were 
      formulated for testing responsiveness. RESULTS: The effect size of treatment 
      measured with the Mini-BESTest was 0.44, revealing moderate responsiveness. AUCs 
      were 0.75, 0.82 and 0.59 for the patient-rated GRC, physiotherapist-rated GRC and 
      ABC-5L, respectively. There was a moderate correlation between changes in the 
      Mini-BESTest and patient-rated (r(s) = 0.42) or physiotherapist-rated (r(s) = 
      0.62) GRC scores. Conversely, a low correlation (r(s) = 0.17) was found between 
      changes in the Mini-BESTest and ABC-5L. Consequently, 72.7% of hypotheses were 
      met. The Mini-BESTest MCID was between 3.4 and 4.0 when calculated with 
      distribution and anchor-based methods, respectively. SIGNIFICANCE: The 
      Mini-BESTest showed moderate responsiveness for detecting treatment-related 
      improvement in dynamic balance. A 4.0-point MCID value is useful to identify 
      clinical effects of balance rehabilitation in a single patient with PD. Values 
      ranging from 3.4 and 4.0 are recommended for interpretation of results at a group 
      level.
CI  - Copyright (c) 2020 Elsevier B.V. All rights reserved.
FAU - Godi, Marco
AU  - Godi M
AD  - Division of Physical Medicine and Rehabilitation, ICS Maugeri SPA SB, IRCCS, 
      Institute of Veruno, Italy. Electronic address: marco.godi@icsmaugeri.it.
FAU - Arcolin, Ilaria
AU  - Arcolin I
AD  - Division of Physical Medicine and Rehabilitation, ICS Maugeri SPA SB, IRCCS, 
      Institute of Veruno, Italy. Electronic address: ilaria.arcolin@icsmaugeri.it.
FAU - Giardini, Marica
AU  - Giardini M
AD  - Division of Physical Medicine and Rehabilitation, ICS Maugeri SPA SB, IRCCS, 
      Institute of Veruno, Italy. Electronic address: marica.giardini@icsmaugeri.it.
FAU - Corna, Stefano
AU  - Corna S
AD  - Division of Physical Medicine and Rehabilitation, ICS Maugeri SPA SB, IRCCS, 
      Institute of Veruno, Italy. Electronic address: stefano.corna@icsmaugeri.it.
FAU - Schieppati, Marco
AU  - Schieppati M
AD  - ICS Maugeri SPA SB, IRCCS, Institute of Pavia, Italy. Electronic address: 
      marco.schieppati@icsmaugeri.it.
LA  - eng
PT  - Journal Article
DEP - 20200517
PL  - England
TA  - Gait Posture
JT  - Gait & posture
JID - 9416830
SB  - IM
MH  - Aged
MH  - Area Under Curve
MH  - Disability Evaluation
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Minimal Clinically Important Difference
MH  - Parkinson Disease/*diagnosis/*rehabilitation
MH  - *Postural Balance
MH  - *Psychometrics
MH  - ROC Curve
MH  - Reproducibility of Results
OTO - NOTNLM
OT  - Mini-BESTest
OT  - Minimal clinically important difference
OT  - Parkinson's Disease
OT  - Rehabilitation
OT  - Responsiveness
COIS- Declaration of competing interest The authors have no conflict of interest to 
      declare.
EDAT- 2020/05/29 06:00
MHDA- 2021/04/10 06:00
CRDT- 2020/05/29 06:00
PHST- 2019/11/20 00:00 [received]
PHST- 2020/04/30 00:00 [revised]
PHST- 2020/05/06 00:00 [accepted]
PHST- 2020/05/29 06:00 [pubmed]
PHST- 2021/04/10 06:00 [medline]
PHST- 2020/05/29 06:00 [entrez]
AID - S0966-6362(20)30154-5 [pii]
AID - 10.1016/j.gaitpost.2020.05.004 [doi]
PST - ppublish
SO  - Gait Posture. 2020 Jul;80:14-19. doi: 10.1016/j.gaitpost.2020.05.004. Epub 2020 
      May 17.