PMID- 32468359
OWN - NLM
STAT- MEDLINE
DCOM- 20200728
LR  - 20200728
IS  - 1614-7499 (Electronic)
IS  - 0944-1344 (Linking)
VI  - 27
IP  - 24
DP  - 2020 Aug
TI  - Acrylamide content of collected food products from Tehran's market: a risk 
      assessment study.
PG  - 30558-30570
LID - 10.1007/s11356-020-09323-w [doi]
AB  - Acrylamide concentration in food products collected from the Tehran market was 
      investigated by the aid of a dispersive liquid-liquid microextraction (DLLME) 
      system coupled with gas chromatography-mass spectrometry (GC-MS). Also, the 
      dietary exposure distribution and related potential risk for acrylamide ingestion 
      were estimated by the Monte Carlo simulation (MCS). The highest and lowest mean 
      concentration of acrylamide was detected in coffee and roasted nuts samples as 
      549 and 133 mug/kg, respectively. The mean acrylamide dietary exposure values for 
      children (3-10 years), adolescents (11-17 years), adults (18-60 years), and 
      seniors (61-96 years) were estimated to be 1.81, 1.02, 0.61, and 0.53 mug/kg body 
      weight (BW)/day, respectively. In all age groups, except children, the estimated 
      exposure in men and boys was higher than that in women and girls. Bread, despite 
      containing low acrylamide content groups (157 mug/kg while compared with other, 
      except roasted nuts), showed with the highest contribution rate in all age groups 
      due to its high consumption rate. The estimated incremental lifetime cancer risk 
      (ILCR) for all age groups was noted as greater than 10(-4) indicating serious 
      risk to the population. Moreover, the margin of exposure (MOE) values based on 
      carcinogenicity showed health concern to all age groups (< 10,000). Regarding the 
      non-carcinogenic risk, the target hazard quotient (THQ) was lower than 1, and MOE 
      based on neurotoxicity was higher than 125 (safety thresholds), which represented 
      negligible and ignorable risk in all age groups except in a small group of 
      children and adolescents. Graphical abstract.
FAU - Nematollahi, Amene
AU  - Nematollahi A
AD  - Department of Food Science and Technology, Faculty of Nutrition Science, Food 
      Science and Technology/National Nutrition and Food Technology Research Institute, 
      Shahid Beheshti University of Medical Sciences, Tehran, Iran.
FAU - Kamankesh, Marzieh
AU  - Kamankesh M
AD  - Department of Food Science and Technology, Faculty of Nutrition Science, Food 
      Science and Technology/National Nutrition and Food Technology Research Institute, 
      Shahid Beheshti University of Medical Sciences, Tehran, Iran.
FAU - Hosseini, Hedayat
AU  - Hosseini H
AD  - Department of Food Science and Technology, Faculty of Nutrition Science, Food 
      Science and Technology/National Nutrition and Food Technology Research Institute, 
      Shahid Beheshti University of Medical Sciences, Tehran, Iran.
FAU - Ghasemi, Jahanbakhsh
AU  - Ghasemi J
AD  - Faculty of Chemistry, University of Tehran, Tehran, Iran.
FAU - Hosseini-Esfahani, Firoozeh
AU  - Hosseini-Esfahani F
AD  - Nutrition and Endocrine Research Center and Obesity Research Center, Research 
      Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, 
      Tehran, Iran.
FAU - Mohammadi, Abdorreza
AU  - Mohammadi A
AD  - Department of Food Science and Technology, Faculty of Nutrition Science, Food 
      Science and Technology/National Nutrition and Food Technology Research Institute, 
      Shahid Beheshti University of Medical Sciences, Tehran, Iran. 
      ab.mohammadi@sbmu.ac.ir.
FAU - Mousavi Khaneghah, Amin
AU  - Mousavi Khaneghah A
AUID- ORCID: 0000-0001-5769-0004
AD  - Department of Food Science, Faculty of Food Engineering, University of Campinas 
      (UNICAMP), Monteiro Lobato, 80, Caixa Postal 6121, Campinas, Sao Paulo, 
      13083-862, Brazil. mousavi@unicamp.br.
LA  - eng
PT  - Journal Article
DEP - 20200528
PL  - Germany
TA  - Environ Sci Pollut Res Int
JT  - Environmental science and pollution research international
JID - 9441769
RN  - 20R035KLCI (Acrylamide)
SB  - IM
MH  - Acrylamide/*analysis
MH  - Adolescent
MH  - Adult
MH  - Child
MH  - Dietary Exposure
MH  - Female
MH  - Food Contamination/*analysis
MH  - Humans
MH  - Iran
MH  - Male
MH  - Risk Assessment
OTO - NOTNLM
OT  - Acrylamide
OT  - Contamination
OT  - Dietary exposure
OT  - Dispersive liquid-liquid microextraction (DLLME)
OT  - Food products
OT  - Monte Carlo simulation
OT  - Risk assessment
EDAT- 2020/05/30 06:00
MHDA- 2020/07/29 06:00
CRDT- 2020/05/30 06:00
PHST- 2019/11/15 00:00 [received]
PHST- 2020/05/14 00:00 [accepted]
PHST- 2020/05/30 06:00 [pubmed]
PHST- 2020/07/29 06:00 [medline]
PHST- 2020/05/30 06:00 [entrez]
AID - 10.1007/s11356-020-09323-w [pii]
AID - 10.1007/s11356-020-09323-w [doi]
PST - ppublish
SO  - Environ Sci Pollut Res Int. 2020 Aug;27(24):30558-30570. doi: 
      10.1007/s11356-020-09323-w. Epub 2020 May 28.