PMID- 32469724
OWN - NLM
STAT- MEDLINE
DCOM- 20210514
LR  - 20210514
IS  - 1878-0180 (Electronic)
IS  - 1878-0180 (Linking)
VI  - 108
DP  - 2020 Aug
TI  - Mechanical behaviour of additively manufactured bioactive glass/high density 
      polyethylene composites.
PG  - 103830
LID - S1751-6161(20)30384-2 [pii]
LID - 10.1016/j.jmbbm.2020.103830 [doi]
AB  - Bioactive glass (BAG) is a well-known biomaterial that can form a strong bond 
      with hard and soft tissues and can also aid in bone regeneration. In this study, 
      BAG is added to a polymer to induce bioactivity and to realize fused filament 
      fabrication (FFF) based printing of polymer composites for potential orthopaedic 
      implant applications. BAG (5, 10, and 20 wt%) is melt compounded with high 
      density polyethylene (HDPE) and subsequently extruded into feedstock filament for 
      FFF-printing. Tensile tests on developed filaments reveal that they are stiff 
      enough to resist forces exerted during the printing process. Micrography of 
      printed HDPE/BAG reveals perfect diffusion of raster interface indicating proper 
      selection of printing parameters. Micrography of freeze fractured prints shows 
      the homogeneous distribution and good dispersion of filler across the matrix. The 
      tensile, flexural, and compressive modulus of FFF-printed HDPE/BAG parts 
      increases with filler addition. BAG addition to the HDPE matrix enhances flexural 
      and compressive strength. The tensile and flexural behaviour of FFF-prints is 
      comparable to injection molded counterparts. Property maps exhibit the merits of 
      present study over the existing literature pertaining to desired bone properties 
      and polymer composites used in biomedical applications. It is envisioned that the 
      development of HDPE/BAG composites for FFF-printing can lead to possible 
      orthopaedic implants and scaffolds to mimic the bone properties in customised 
      anatomical sites or injuries.
CI  - Copyright (c) 2020 Elsevier Ltd. All rights reserved.
FAU - Jeyachandran, Praveen
AU  - Jeyachandran P
AD  - Additive Manufacturing Laboratory, Department of Mechanical Engineering, National 
      Institute of Technology Karnataka, Surathkal, 575025, India; Advanced 
      Manufacturing Laboratory, Department of Mechanical Engineering, National 
      Institute of Technology Karnataka, Surathkal, 575025, India.
FAU - Bontha, Srikanth
AU  - Bontha S
AD  - Additive Manufacturing Laboratory, Department of Mechanical Engineering, National 
      Institute of Technology Karnataka, Surathkal, 575025, India.
FAU - Bodhak, Subhadip
AU  - Bodhak S
AD  - Bioceramics and Coating Division, CSIR-Central Glass and Ceramic Research 
      Institute, Kolkata, 700032, India.
FAU - Balla, Vamsi Krishna
AU  - Balla VK
AD  - Bioceramics and Coating Division, CSIR-Central Glass and Ceramic Research 
      Institute, Kolkata, 700032, India.
FAU - Kundu, Biswanath
AU  - Kundu B
AD  - Bioceramics and Coating Division, CSIR-Central Glass and Ceramic Research 
      Institute, Kolkata, 700032, India.
FAU - Doddamani, Mrityunjay
AU  - Doddamani M
AD  - Advanced Manufacturing Laboratory, Department of Mechanical Engineering, National 
      Institute of Technology Karnataka, Surathkal, 575025, India. Electronic address: 
      mrdoddamani@nitk.edu.in.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20200430
PL  - Netherlands
TA  - J Mech Behav Biomed Mater
JT  - Journal of the mechanical behavior of biomedical materials
JID - 101322406
RN  - 0 (Biocompatible Materials)
RN  - 9002-88-4 (Polyethylene)
SB  - IM
MH  - Biocompatible Materials
MH  - Bone and Bones
MH  - Compressive Strength
MH  - *Glass
MH  - *Polyethylene
OTO - NOTNLM
OT  - Bioactive glass
OT  - Filament
OT  - Fused filament fabrication
OT  - HDPE
OT  - Mechanical behaviour
OT  - Polymer
OT  - Polymer composites
COIS- Declaration of competing interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2020/05/30 06:00
MHDA- 2021/05/15 06:00
CRDT- 2020/05/30 06:00
PHST- 2020/04/08 00:00 [received]
PHST- 2020/04/22 00:00 [revised]
PHST- 2020/04/23 00:00 [accepted]
PHST- 2020/05/30 06:00 [entrez]
PHST- 2020/05/30 06:00 [pubmed]
PHST- 2021/05/15 06:00 [medline]
AID - S1751-6161(20)30384-2 [pii]
AID - 10.1016/j.jmbbm.2020.103830 [doi]
PST - ppublish
SO  - J Mech Behav Biomed Mater. 2020 Aug;108:103830. doi: 10.1016/j.jmbbm.2020.103830. 
      Epub 2020 Apr 30.