PMID- 32475867
OWN - NLM
STAT- MEDLINE
DCOM- 20210810
LR  - 20210810
IS  - 1348-4540 (Electronic)
IS  - 0918-8959 (Linking)
VI  - 67
IP  - 9
DP  - 2020 Sep 28
TI  - Parathyroid carcinoma coexisting with multiple parathyroid adenomas: a case 
      report.
PG  - 963-967
LID - 10.1507/endocrj.EJ20-0139 [doi]
AB  - Primary hyperparathyroidism is usually caused by parathyroid adenoma; however, 
      parathyroid carcinoma is a rare cause. We report a rare case of 74-year-old 
      female of primary hyperparathyroidism caused by parathyroid carcinoma (PC) and 
      coexisting multiple parathyroid adenomas. She was referred to our hospital for 
      primary hyperparathyroidism and a suspected thyroid tumor. She had no family 
      history of malignant tumor. Computed tomography (CT) and ultrasonography of the 
      neck revealed some masses posterior to both thyroid lobes. Those masses were 
      believed to be parathyroid lesions. However, another mass located posterior to 
      the right upper thyroid lobe seemed to be heterogeneous, which indicated a 
      malignant thyroid tumor as well as parathyroid tumor. The preoperative diagnosis 
      was multiple parathyroid adenoma and suspicious incidental thyroid carcinoma. 
      Therefore, the patient underwent total parathyroidectomy and thyroidectomy. The 
      histopathological diagnosis was parathyroid carcinoma coexisting with multiple 
      parathyroid adenomas. There was no evidence of recurrence at 1 year after the 
      surgery. It was difficult to diagnose PC preoperatively. Few rare cases of PC 
      coexisting with parathyroid adenoma in multiple endocrine neoplasia type 1 (MEN1) 
      have been reported. Therefore, careful follow-up was necessary considering the 
      possibility of MEN1, though she did not wish for a genetic examination.
FAU - Takenobu, Masao
AU  - Takenobu M
AD  - Kusatsu General Hosipital, Otolaryngology Head and Neck Thyroid Surgery, Shiga 
      525-8585, Japan.
FAU - Moritani, Sueyoshi
AU  - Moritani S
AD  - Kusatsu General Hosipital, Otolaryngology Head and Neck Thyroid Surgery, Shiga 
      525-8585, Japan.
FAU - Kawamoto, Katsuyuki
AU  - Kawamoto K
AD  - Kusatsu General Hosipital, Otolaryngology Head and Neck Thyroid Surgery, Shiga 
      525-8585, Japan.
FAU - Yoshioka, Kana
AU  - Yoshioka K
AD  - Kusatsu General Hosipital, Otolaryngology Head and Neck Thyroid Surgery, Shiga 
      525-8585, Japan.
FAU - Kitano, Hiroya
AU  - Kitano H
AD  - Kusatsu General Hosipital, Otolaryngology Head and Neck Thyroid Surgery, Shiga 
      525-8585, Japan.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20200530
PL  - Japan
TA  - Endocr J
JT  - Endocrine journal
JID - 9313485
SB  - IM
MH  - Adenoma/*complications/diagnostic imaging/pathology
MH  - Aged
MH  - Carcinoma/*complications/diagnostic imaging/pathology
MH  - Female
MH  - Humans
MH  - Parathyroid Glands/*diagnostic imaging/pathology
MH  - Parathyroid Neoplasms/*complications/diagnostic imaging/pathology
MH  - Tomography, X-Ray Computed
MH  - Ultrasonography
OTO - NOTNLM
OT  - Multiple parathyroid adenoma
OT  - Parathyroid adenoma
OT  - Parathyroid carcinoma
OT  - Primary hyperparathyroidism
EDAT- 2020/06/02 06:00
MHDA- 2021/08/11 06:00
CRDT- 2020/06/02 06:00
PHST- 2020/06/02 06:00 [pubmed]
PHST- 2021/08/11 06:00 [medline]
PHST- 2020/06/02 06:00 [entrez]
AID - 10.1507/endocrj.EJ20-0139 [doi]
PST - ppublish
SO  - Endocr J. 2020 Sep 28;67(9):963-967. doi: 10.1507/endocrj.EJ20-0139. Epub 2020 
      May 30.