PMID- 32476579 OWN - NLM STAT- MEDLINE DCOM- 20210514 LR - 20210514 IS - 1744-5205 (Electronic) IS - 0882-0538 (Linking) VI - 35 IP - 3 DP - 2020 Apr 2 TI - Biofeedback Low Vision Rehabilitation with Retimax Vision Trainer in Patients with Advanced Age-related Macular Degeneration: A Pilot Study. PG - 164-169 LID - 10.1080/08820538.2020.1774624 [doi] AB - PURPOSE: To evaluate the effectiveness of Visual Evoked Potential (VEP) biofeedback rehabilitation in selected low vision patients with advanced age-related macular degeneration (AMD). DESIGN: Retrospective observational cohort study. METHODS: Patients affected by advanced AMD, central macular atrophy with unstable fixation and best corrected visual acuity (BCVA) between 20/100 and 20/320 were considered. Selected patients underwent fundus photography and microperimetry with fixation analysis for the selected eye (highest BCVA). Ten consecutive training sessions of 10 min each were performed twice a week in the selected eye with Retimax Vision Trainer (CSO, Florence). BCVA, reading acuity and reading speed, contrast sensitivity, fixation, retinal sensitivity and quality of life questionnaire (VFQ-25) were evaluated at baseline and 7 days following the final session. RESULTS: Significant improvements in terms of BCVA [p = .011], reading speed [p = .007], VFQ-25 score [p = .007], retinal sensitivity [p = .021] and fixation stability in the central 2 degrees and 4 degrees [p = .048; p = .037] post-treatment were observed for the 9 patients enrolled, with insignificant improvements observed in reading acuity and contrast sensitivity [p = .335; p = .291]. CONCLUSIONS: Preliminary results support VEP biofeedback rehabilitation improvements for visual function and quality of life in advanced AMD patients with low vision. FAU - Verdina, Tommaso AU - Verdina T AUID- ORCID: 0000-0001-7877-4485 AD - Institute of Ophthalmology, University of Modena and Reggio Emilia , Modena, Italy. FAU - Piaggi, Stefania AU - Piaggi S AD - Institute of Ophthalmology, University of Modena and Reggio Emilia , Modena, Italy. FAU - Peschiera, Riccardo AU - Peschiera R AD - Institute of Ophthalmology, University of Modena and Reggio Emilia , Modena, Italy. FAU - Russolillo, Valeria AU - Russolillo V AD - Institute of Ophthalmology, University of Modena and Reggio Emilia , Modena, Italy. FAU - Ferraro, Vanessa AU - Ferraro V AD - Institute of Ophthalmology, University of Modena and Reggio Emilia , Modena, Italy. FAU - Chester, Johanna AU - Chester J AD - Department of Dermatology, University of Modena and Reggio Emilia , Modena, Italy. FAU - Mastropasqua, Rodolfo AU - Mastropasqua R AD - Institute of Ophthalmology, University of Modena and Reggio Emilia , Modena, Italy. FAU - Cavallini, Gian Maria AU - Cavallini GM AD - Institute of Ophthalmology, University of Modena and Reggio Emilia , Modena, Italy. LA - eng PT - Journal Article PT - Observational Study PT - Video-Audio Media DEP - 20200601 PL - England TA - Semin Ophthalmol JT - Seminars in ophthalmology JID - 8610759 SB - IM MH - Aged MH - Aged, 80 and over MH - *Biofeedback, Psychology MH - Evoked Potentials, Visual MH - Female MH - Humans MH - Macular Degeneration/*physiopathology/*rehabilitation MH - Male MH - Pilot Projects MH - Quality of Life MH - Retrospective Studies MH - Surveys and Questionnaires MH - Vision, Low/*rehabilitation MH - Visual Acuity OTO - NOTNLM OT - Age-related macular degeneration (AMD) OT - biofeedback rehabilitation OT - low vision OT - microperimetry OT - plasticity of fixation EDAT- 2020/06/02 06:00 MHDA- 2021/05/15 06:00 CRDT- 2020/06/02 06:00 PHST- 2020/06/02 06:00 [pubmed] PHST- 2021/05/15 06:00 [medline] PHST- 2020/06/02 06:00 [entrez] AID - 10.1080/08820538.2020.1774624 [doi] PST - ppublish SO - Semin Ophthalmol. 2020 Apr 2;35(3):164-169. doi: 10.1080/08820538.2020.1774624. Epub 2020 Jun 1.