PMID- 32483688
OWN - NLM
STAT- MEDLINE
DCOM- 20210514
LR  - 20210514
IS  - 1590-3478 (Electronic)
IS  - 1590-1874 (Linking)
VI  - 41
IP  - 11
DP  - 2020 Nov
TI  - Optical coherence tomography angiography in nonarteritic anterior ischemic optic 
      neuropathy due to optic nerve head drusen.
PG  - 3349-3351
LID - 10.1007/s10072-020-04493-4 [doi]
AB  - Optic nerve head drusen (ONHD) are typically benign hyaline and calcified 
      concretions located within the optic nerve. Initially asymptomatic, they can 
      increase slowly in size and number over time, and they can cause mechanical 
      stress at the axons of the optic nerve and progressively lead to a loss of the 
      visual field and papillary vascular changes. Here, we reported a rare case of a 
      young patient with bilateral ONHD complicated by a nonarteritic anterior ischemic 
      optic neuropathy (NAION) in the right eye. The aim of this case was to evaluate, 
      using optical coherence tomography angiography (OCTA), the vascular network of 
      the papillary region in both eyes in the presence of this ischemic event 
      associated to ONHD. At OCTA examination, the whole papillary region revealed a 
      general rarefaction of the vascular network, but it turned out to be greater in 
      the right eye affected by nonarteritic anterior ischemic optic neuropathy than in 
      fellow eye. Therefore, these findings demonstrated that ONHD may determine 
      significant ischemic events of the optic nerve and OCTA represents a valid and 
      noninvasive tool in the diagnosis and in the pathogenesis of these rare cases of 
      NAION associated to ONHD in young patients.
FAU - Cennamo, Gilda
AU  - Cennamo G
AUID- ORCID: 0000-0003-4253-1929
AD  - Department of Public Health, Eye Clinic, University of Naples Federico II, Via S. 
      Pansini 5, 80133, Naples, Italy. xgilda@hotmail.com.
FAU - Montorio, Daniela
AU  - Montorio D
AD  - Department of Neurosciences, Reproductive Sciences and Dentistry, University of 
      Naples Federico II, Naples, Italy.
FAU - Giunta, Piera
AU  - Giunta P
AD  - Department of Neurosciences, Reproductive Sciences and Dentistry, University of 
      Naples Federico II, Naples, Italy.
FAU - Tranfa, Fausto
AU  - Tranfa F
AD  - Department of Neurosciences, Reproductive Sciences and Dentistry, University of 
      Naples Federico II, Naples, Italy.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20200601
PL  - Italy
TA  - Neurol Sci
JT  - Neurological sciences : official journal of the Italian Neurological Society and 
      of the Italian Society of Clinical Neurophysiology
JID - 100959175
SB  - IM
MH  - Angiography
MH  - Humans
MH  - *Optic Disk/diagnostic imaging
MH  - *Optic Neuropathy, Ischemic/complications/diagnostic imaging
MH  - Tomography, Optical Coherence
MH  - Visual Fields
OTO - NOTNLM
OT  - Nonarteritic anterior ischemic optic neuropathy
OT  - Optic nerve head drusen
OT  - Optical coherence tomography angiography
EDAT- 2020/06/03 06:00
MHDA- 2021/05/15 06:00
CRDT- 2020/06/03 06:00
PHST- 2020/03/17 00:00 [received]
PHST- 2020/05/28 00:00 [accepted]
PHST- 2020/06/03 06:00 [pubmed]
PHST- 2021/05/15 06:00 [medline]
PHST- 2020/06/03 06:00 [entrez]
AID - 10.1007/s10072-020-04493-4 [pii]
AID - 10.1007/s10072-020-04493-4 [doi]
PST - ppublish
SO  - Neurol Sci. 2020 Nov;41(11):3349-3351. doi: 10.1007/s10072-020-04493-4. Epub 2020 
      Jun 1.