PMID- 32483744
OWN - NLM
STAT- MEDLINE
DCOM- 20210414
LR  - 20210414
IS  - 1708-0428 (Electronic)
IS  - 0960-8923 (Linking)
VI  - 30
IP  - 9
DP  - 2020 Sep
TI  - Effect of Surgically Induced Weight Loss on Biomarkers of Endothelial 
      Dysfunction: a Systematic Review and Meta-Analysis.
PG  - 3549-3560
LID - 10.1007/s11695-020-04710-1 [doi]
AB  - BACKGROUND: This meta-analysis was performed to assess the effects of bariatric 
      surgery (BS) on the selected markers of endothelial dysfunction, including 
      monocyte chemoattractant protein-1 (MCP-1), intercellular adhesion molecule 1 
      (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin. METHODS: 
      PubMed, Scopus, and Google scholar were systematically searched to identify 
      related studies published from inception to November 2019 to find eligible 
      studies. RESULTS: A total of 29 different studies were included. BS reduced the 
      concentrations of MCP-1 (weighted mean difference (WMD) = - 58.91; 95%CI 
      (confidence interval), - 77.10 to - 40.72; P = < 0.001), ICAM-1 (WMD = - 36.58; 
      95%CI, - 49.65 to - 23.52; P = < 0.001), and E-selectin (WMD = - 11.22; 95%CI, 
      - 14.43 to - 8.01; P < 0.001), but had no significant effect on VCAM-1. 
      CONCLUSION: Bariatric surgery reduces circulating concentration of MCP-1, ICAM-1, 
      and E-selectin, but not VCAM-1.
FAU - Seyyedi, Javad
AU  - Seyyedi J
AD  - Department of Medical Surgical Nursing, School of Nursing & Midwifery, Tehran 
      University of Medical Sciences, Tehran, Iran.
FAU - Alizadeh, Shahab
AU  - Alizadeh S
AUID- ORCID: 0000-0003-1097-8814
AD  - Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, 
      Tehran University of Medical Sciences, Tehran, Iran. sh_alizadeh@razi.tums.ac.ir.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
PL  - United States
TA  - Obes Surg
JT  - Obesity surgery
JID - 9106714
RN  - 0 (Biomarkers)
RN  - 0 (E-Selectin)
RN  - 0 (Vascular Cell Adhesion Molecule-1)
RN  - 126547-89-5 (Intercellular Adhesion Molecule-1)
SB  - IM
MH  - Biomarkers
MH  - E-Selectin
MH  - Endothelium, Vascular
MH  - Humans
MH  - Intercellular Adhesion Molecule-1
MH  - *Obesity, Morbid/surgery
MH  - Vascular Cell Adhesion Molecule-1
MH  - *Weight Loss
OTO - NOTNLM
OT  - Bariatric surgery
OT  - E-selectin
OT  - Endothelial dysfunction
OT  - ICAM-1
OT  - MCP-1
OT  - VCAM-1
EDAT- 2020/06/03 06:00
MHDA- 2021/04/15 06:00
CRDT- 2020/06/03 06:00
PHST- 2020/06/03 06:00 [pubmed]
PHST- 2021/04/15 06:00 [medline]
PHST- 2020/06/03 06:00 [entrez]
AID - 10.1007/s11695-020-04710-1 [pii]
AID - 10.1007/s11695-020-04710-1 [doi]
PST - ppublish
SO  - Obes Surg. 2020 Sep;30(9):3549-3560. doi: 10.1007/s11695-020-04710-1.