PMID- 32485520
OWN - NLM
STAT- MEDLINE
DCOM- 20201207
LR  - 20201214
IS  - 1872-6976 (Electronic)
IS  - 0167-4943 (Linking)
VI  - 89
DP  - 2020 Jul-Aug
TI  - Diagnostic differences and agreement between the original and revised European 
      Working Group (EWGSOP) consensus definition for sarcopenia in community-dwelling 
      older adults with type 2 diabetes mellitus.
PG  - 104081
LID - S0167-4943(20)30075-3 [pii]
LID - 10.1016/j.archger.2020.104081 [doi]
AB  - AIM: We aimed to compare diagnostic differences for identification of sarcopenia 
      using the original operational definition developed by the European Working Group 
      on Sarcopenia in Older People (EWGSOP1) and the most recently revised EWGSOP2 
      definition in community dwelling older adults with type 2 diabetes mellitus 
      (T2DM). METHODS: Appendicular Lean Mass (ALM) corrected for height (ALM/m(2)) was 
      assessed by dual energy X-ray absorptiometry. Muscle strength was assessed using 
      hand-grip strength (HGS) or chair stands, and the Short Physical Performance 
      Battery (SPPB) and gait speed were used to evaluate lower extremity physical 
      function. Cohen's kappa (kappa) statistic was applied to determine the degree of 
      agreement between the two definitions. Chi-square analysis with Bonferroni post 
      hoc corrections were applied to determine differences in the prevalence of 
      sarcopenic case-findings. RESULTS: A total of n = 87 older adults (71.2 +/- 8.2 
      years; 66.7% males; BMI: 29.5 +/- 5.8 kg/m2) were included. Agreement between the 
      two definitions was low and non-significant (kappa value = 0.118; P =  0.144). 
      Significantly more cases of sarcopenia were identified when applying the EWGSOP1 
      definition (EWGSOP1: n = 6 (7%); EWGSOP2: n = 2 (2%); P = 0.004). No sex specific 
      differences were observed. Only 2 of the 6 (33.3%) cases of sarcopenia identified 
      by EWGSOP1 were also identified as sarcopenic when applying the EWGSOP2 
      diagnostic criteria. CONCLUSIONS: We showed significant discordance and limited 
      overlap in the number of sarcopenic case-findings when applying both EWGSOP 
      definitions. It is unknown as to whether the new diagnostic criteria are better 
      at identifying adverse clinical outcomes in patients with T2DM. Future 
      investigation is therefore warranted.
CI  - Copyright (c) 2020 Elsevier B.V. All rights reserved.
FAU - Villani, Anthony
AU  - Villani A
AD  - School of Health and Sport Sciences, University of the Sunshine Coast, 
      Queensland, Australia. Electronic address: avillani@usc.edu.au.
FAU - McClure, Rebecca
AU  - McClure R
AD  - School of Health and Sport Sciences, University of the Sunshine Coast, 
      Queensland, Australia.
FAU - Barrett, Michelle
AU  - Barrett M
AD  - School of Health and Sport Sciences, University of the Sunshine Coast, 
      Queensland, Australia.
FAU - Scott, David
AU  - Scott D
AD  - Department of Medicine, School of Clinical Sciences at Monash Health, Monash 
      University, Clayton, Victoria 3168, Australia; Department of Medicine and 
      Australian Institute of Musculoskeletal Science, Melbourne Medical School - 
      Western Campus, The University of Melbourne, St Albans, Victoria, 3021, 
      Australia.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20200421
PL  - Netherlands
TA  - Arch Gerontol Geriatr
JT  - Archives of gerontology and geriatrics
JID - 8214379
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Consensus
MH  - *Diabetes Mellitus, Type 2/diagnosis/epidemiology
MH  - Female
MH  - Hand Strength
MH  - Humans
MH  - Independent Living
MH  - Male
MH  - Prevalence
MH  - *Sarcopenia/diagnosis/epidemiology
OTO - NOTNLM
OT  - EWGSOP
OT  - EWGSOP2
OT  - Sarcopenia
OT  - older adults
OT  - type 2 diabetes
EDAT- 2020/06/03 06:00
MHDA- 2020/12/15 06:00
CRDT- 2020/06/03 06:00
PHST- 2020/02/18 00:00 [received]
PHST- 2020/03/25 00:00 [revised]
PHST- 2020/04/14 00:00 [accepted]
PHST- 2020/06/03 06:00 [pubmed]
PHST- 2020/12/15 06:00 [medline]
PHST- 2020/06/03 06:00 [entrez]
AID - S0167-4943(20)30075-3 [pii]
AID - 10.1016/j.archger.2020.104081 [doi]
PST - ppublish
SO  - Arch Gerontol Geriatr. 2020 Jul-Aug;89:104081. doi: 
      10.1016/j.archger.2020.104081. Epub 2020 Apr 21.