PMID- 32487225
OWN - NLM
STAT- MEDLINE
DCOM- 20201221
LR  - 20201221
IS  - 1471-2318 (Electronic)
IS  - 1471-2318 (Linking)
VI  - 20
IP  - 1
DP  - 2020 Jun 1
TI  - The impact of hospitalisation to geriatric wards on the use of medications and 
      potentially inappropriate medications - a health register study.
PG  - 190
LID - 10.1186/s12877-020-01585-w [doi]
LID - 190
AB  - BACKGROUND: The use of potentially inappropriate medications (PIMs) are 
      associated with negative health effects for older adults. The purpose of this 
      study was to apply national register data to investigate the impact of 
      hospitalisation to geriatric wards in Norway on the use of medications and PIMs, 
      and to compare two explicit PIM identification tools. METHODS: We included 715 
      patients >/=65 years (mean 82.5, SD = 7.8) admitted to Norwegian geriatric wards in 
      2013 identified from The Norwegian Patient Registry, and collected their 
      medication use from the Norwegian Prescription Database. Medication use before 
      and after hospitalisation was compared and screened for PIMs applying a subset of 
      the European Union (EU)(7)-PIM list and the Norwegian General Practice - Nursing 
      Home (NORGEP-NH) list part A and B. RESULTS: The mean number of medications 
      increased from 6.5 (SD = 3.5) before to 7.5 (SD = 3.5) (CI:1.2-0.8, p < 0.001) 
      after hospitalisation. The proportion of patients with PIMs increased from before 
      to after hospitalisation according to the EU(7)-PIM list (from 62.4 to 69.2%, 
      p < 0.001), but not according to The NORGEP-NH list (from 49.9 to 50.6%, 
      p = 0.73). The EU(7)-PIM list and the NORGEP-NH list had more than 70% agreement 
      on the classification of patients as PIM users. CONCLUSIONS: Medication use 
      increased after hospitalisation to geriatric wards. We did not find that 
      geriatric hospital care leads to a general improvement in PIM use after 
      hospitalisation. According to a subset of the EU(7)-PIM list, PIM use increased 
      after hospitalisation. This increase was not identified by the NORGEP-NH list 
      part A and B. It is feasible to use health register data to investigate the 
      impact of hospitalisation to geriatric wards on medication use and PIMs.
FAU - Johansen, Jeanette Schultz
AU  - Johansen JS
AUID- ORCID: 0000-0001-7052-5142
AD  - Department of Pharmacy, Faculty of Health Sciences, UiT the Arctic University of 
      Norway, N-9037, Tromso, Norway. jeajoh@uit.no.
FAU - Halvorsen, Kjell H
AU  - Halvorsen KH
AD  - Department of Pharmacy, Faculty of Health Sciences, UiT the Arctic University of 
      Norway, N-9037, Tromso, Norway.
FAU - Svendsen, Kristian
AU  - Svendsen K
AD  - Department of Pharmacy, Faculty of Health Sciences, UiT the Arctic University of 
      Norway, N-9037, Tromso, Norway.
AD  - Hospital Pharmacy of North Norway Trust, Tromso, Norway.
FAU - Havnes, Kjerstin
AU  - Havnes K
AD  - Department of Pharmacy, Faculty of Health Sciences, UiT the Arctic University of 
      Norway, N-9037, Tromso, Norway.
FAU - Garcia, Beate H
AU  - Garcia BH
AD  - Department of Pharmacy, Faculty of Health Sciences, UiT the Arctic University of 
      Norway, N-9037, Tromso, Norway.
AD  - Hospital Pharmacy of North Norway Trust, Tromso, Norway.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20200601
PL  - England
TA  - BMC Geriatr
JT  - BMC geriatrics
JID - 100968548
SB  - IM
MH  - Aged
MH  - Hospitalization
MH  - Hospitals
MH  - Humans
MH  - *Inappropriate Prescribing
MH  - Norway/epidemiology
MH  - *Potentially Inappropriate Medication List
PMC - PMC7268415
OTO - NOTNLM
OT  - Drug therapy
OT  - EU(7)-PIM list
OT  - Health register data
OT  - Health services for the aged
OT  - Hospitalization
OT  - NORGEP-NH list
OT  - Potentially inappropriate medications
COIS- The authors declare that there are no conflicts of interest.
EDAT- 2020/06/04 06:00
MHDA- 2020/12/22 06:00
PMCR- 2020/06/01
CRDT- 2020/06/04 06:00
PHST- 2020/03/09 00:00 [received]
PHST- 2020/05/19 00:00 [accepted]
PHST- 2020/06/04 06:00 [entrez]
PHST- 2020/06/04 06:00 [pubmed]
PHST- 2020/12/22 06:00 [medline]
PHST- 2020/06/01 00:00 [pmc-release]
AID - 10.1186/s12877-020-01585-w [pii]
AID - 1585 [pii]
AID - 10.1186/s12877-020-01585-w [doi]
PST - epublish
SO  - BMC Geriatr. 2020 Jun 1;20(1):190. doi: 10.1186/s12877-020-01585-w.