PMID- 32488806 OWN - NLM STAT- MEDLINE DCOM- 20210525 LR - 20210525 IS - 0973-7693 (Electronic) IS - 0019-5456 (Linking) VI - 88 IP - 1 DP - 2021 Jan TI - General Movement Assessment Predicts Neuro-Developmental Outcome in Very Low Birth Weight Infants at Two Years - A Five-Year Observational Study. PG - 28-33 LID - 10.1007/s12098-020-03365-1 [doi] AB - OBJECTIVE: To assess the value of general movements (GMs) in predicting the neurodevelopmental outcome using Bayley Scale of Infant Development III (BSID-III) at two years of age in very low birth weight (VLBW) infants. METHODS: This is a five-year observational study (January 2012-June 2017). Two hundred twenty-seven VLBW infants were assessed in the neurodevelopmental clinic between Jan 2012 and June 2017. Of these 137 infants had GMs assessments at 3 mo post term (first visit to the clinic). RESULTS: Absence of fidgety movements (FMs) at 3 mo post term had high specificity and negative predictive value for moderate to severe neurodevelopmental outcome in motor, cognition and language domains (composite score less than 70 in the Bayley III scales of Infant development scores). At 3 mo post term, absent FMs had high sensitivity, specificity and negative predictive value (NPV) for cerebral palsy (CP). CONCLUSIONS: GMs assessment at 3 mo post term could be considered as an important screening tool for early identification of VLBW infants who are at risk of neurodevelopmental impairment/cerebral palsy. FAU - Barnes, Fiona AU - Barnes F AD - Neonatal Intensive Care Unit, University Hospital, Crosshouse, Kilmarnock, Ayrshire, KA2 0BE, UK. FAU - Graham, Lynda AU - Graham L AD - Neonatal Intensive Care Unit, University Hospital, Crosshouse, Kilmarnock, Ayrshire, KA2 0BE, UK. FAU - Loganathan, Prakash AU - Loganathan P AD - Neonatal Intensive Care Unit, James Cook University Hospital, Marton road, Middlesbrough, TS4 3BW, UK. AD - Clinical Academic Office, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, UK. FAU - Nair, Vrinda AU - Nair V AUID- ORCID: 0000-0002-7149-4525 AD - Neonatal Intensive Care Unit, James Cook University Hospital, Marton road, Middlesbrough, TS4 3BW, UK. vrinda.nair1@nhs.net. AD - Clinical Academic Office, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, UK. vrinda.nair1@nhs.net. LA - eng PT - Journal Article PT - Observational Study DEP - 20200603 PL - India TA - Indian J Pediatr JT - Indian journal of pediatrics JID - 0417442 SB - IM MH - *Cerebral Palsy/diagnosis/epidemiology MH - Child MH - Child Development MH - Humans MH - Infant MH - Infant, Newborn MH - *Infant, Very Low Birth Weight MH - Movement MH - Sensitivity and Specificity OTO - NOTNLM OT - Cerebral palsy OT - General movements OT - Neurodevelopment EDAT- 2020/06/04 06:00 MHDA- 2021/05/26 06:00 CRDT- 2020/06/04 06:00 PHST- 2019/11/21 00:00 [received] PHST- 2020/05/21 00:00 [accepted] PHST- 2020/06/04 06:00 [pubmed] PHST- 2021/05/26 06:00 [medline] PHST- 2020/06/04 06:00 [entrez] AID - 10.1007/s12098-020-03365-1 [pii] AID - 10.1007/s12098-020-03365-1 [doi] PST - ppublish SO - Indian J Pediatr. 2021 Jan;88(1):28-33. doi: 10.1007/s12098-020-03365-1. Epub 2020 Jun 3.