PMID- 32497752
OWN - NLM
STAT- MEDLINE
DCOM- 20200904
LR  - 20200904
IS  - 1872-9142 (Electronic)
IS  - 0161-5890 (Linking)
VI  - 124
DP  - 2020 Aug
TI  - Characterization of lamprey (Lampetra japonica) tnfr10-like gene: A potential 
      granulocyte marker molecule and its immune functions.
PG  - 25-34
LID - S0161-5890(20)30356-4 [pii]
LID - 10.1016/j.molimm.2020.05.015 [doi]
AB  - Tumor necrosis factor receptor superfamily (TNFRSF) is an ancient protein 
      superfamily. By binding to tumor necrosis factor (TNF), it can participate in 
      inflammatory response, apoptosis, lymphocyte homeostasis and tissue development. 
      Seven TNFR members have previously been identified in lampreys but detailed 
      functions of TNFR members are not yet to be resolved. Here, we demonstrate some 
      of the distinguishing features of TNFR10-like member which belongs to TNFRSF. The 
      immunohistochemical results indicate that the TNFR10-like protein is abundant in 
      vascular epithelial cells of the lamprey typhlosole and gills. The expression of 
      tnfr10-like gene has a significantly increased at transcription level after 
      Vibrio anguillarum, Staphylococcus aureus and Poly (I:C) stimulation. Notably, 
      TNFR10-like is specifically expressed in the granulocytes of lamprey peripheral 
      blood and supraneural body. Besides, overexpression tnfr10-like gene in HEK-293 T 
      cells cause a decrease in cell activity and able to activate nuclear 
      transcription factor-kappaB (NF-kappaB). Together, these results imply that L-TNFR10-like 
      may play a vital role as a potential marker in lamprey granulocytes and may also 
      be involved in regulation of immune response mediated by itself.
CI  - Copyright (c) 2020 Elsevier Ltd. All rights reserved.
FAU - Zhu, Yigao
AU  - Zhu Y
AD  - College of Life Sciences, Liaoning Normal University, Dalian, 116081, China; 
      Lamprey Research Center, Liaoning Normal University, Dalian, 116081, China.
FAU - Li, Jun
AU  - Li J
AD  - College of Life Sciences, Liaoning Normal University, Dalian, 116081, China; 
      Lamprey Research Center, Liaoning Normal University, Dalian, 116081, China.
FAU - Li, Qingwei
AU  - Li Q
AD  - College of Life Sciences, Liaoning Normal University, Dalian, 116081, China; 
      Lamprey Research Center, Liaoning Normal University, Dalian, 116081, China; 
      Collaborative Innovation Center of Seafood Deep Processing, Dalian Polytechnic 
      University, Dalian, 116023, China.
FAU - Pang, Yue
AU  - Pang Y
AD  - College of Life Sciences, Liaoning Normal University, Dalian, 116081, China; 
      Lamprey Research Center, Liaoning Normal University, Dalian, 116081, China. 
      Electronic address: pangyue01@163.com.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20200601
PL  - England
TA  - Mol Immunol
JT  - Molecular immunology
JID - 7905289
RN  - 0 (Fish Proteins)
RN  - 0 (Receptors, Tumor Necrosis Factor)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Fish Proteins/genetics/*immunology
MH  - Granulocytes/*immunology
MH  - HEK293 Cells
MH  - Humans
MH  - Lampreys/genetics/*immunology
MH  - Phylogeny
MH  - Receptors, Tumor Necrosis Factor/genetics/*immunology
OTO - NOTNLM
OT  - Granulocytes
OT  - Immune functions
OT  - Japanese lampreys
OT  - L-TNFR10-like
COIS- Declaration of Competing Interest None.
EDAT- 2020/06/05 06:00
MHDA- 2020/09/05 06:00
CRDT- 2020/06/05 06:00
PHST- 2020/02/15 00:00 [received]
PHST- 2020/05/12 00:00 [revised]
PHST- 2020/05/14 00:00 [accepted]
PHST- 2020/06/05 06:00 [pubmed]
PHST- 2020/09/05 06:00 [medline]
PHST- 2020/06/05 06:00 [entrez]
AID - S0161-5890(20)30356-4 [pii]
AID - 10.1016/j.molimm.2020.05.015 [doi]
PST - ppublish
SO  - Mol Immunol. 2020 Aug;124:25-34. doi: 10.1016/j.molimm.2020.05.015. Epub 2020 Jun 
      1.