PMID- 32500525 OWN - NLM STAT- MEDLINE DCOM- 20210623 LR - 20210623 IS - 1576-6578 (Electronic) IS - 0210-0010 (Linking) VI - 70 IP - 12 DP - 2020 Jun 16 TI - [Non-invasive brain and spinal cord stimulation for motor and functional recovery after a spinal cord injury]. PG - 461-477 LID - 10.33588/rn.7012.2019453 [doi] AB - INTRODUCTION: Spinal cord injury is a traumatic or non-traumatic event that causes an alteration of sensory, motor or autonomic functioning and ultimately affects the physical, psychological and social well-being of the person who suffers it. A comprehensive approach to spinal cord injury requires many health resources and can place a considerable financial burden on patients, their families and the community. AIM: To review the literature published to date on the use of non-invasive brain stimulation, including repetitive transcranial magnetic stimulation (rTMS), transcranial direct current stimulation (tDCS), and transcutaneous non-invasive spinal cord stimulation (tcSCS), as therapeutic strategies to improve the functionality of patients with spinal cord injury. The studies were grouped as addressing either non-invasive brain stimulation or non-invasive spinal cord stimulation. DEVELOPMENT: Altogether 32 studies were identified: 21 involving brain stimulation (14 in rTMS and 7 in tDCS) and 11 with spinal cord stimulation (tcSCS). All the studies were conducted in adult patients who had undergone a spinal cord injury. Despite significant variability in treatment protocols, patient characteristics and clinical assessment, the changes observed were reported in almost all the studies without producing any side effects and with motor or functional improvement. CONCLUSION: Non-invasive brain stimulation, as well as spinal cord stimulation, are promising techniques for the rehabilitation of patients with spinal cord injury due to their novelty, effectiveness and minimal side effects. FAU - Kumru, H AU - Kumru H AD - Institut de Neurorehabilitacio Guttmann-UAB, 08916 Badalona, Espana. FAU - Flores, A AU - Flores A AD - Institut de Neurorehabilitacio Guttmann-UAB, 08916 Badalona, Espana. AD - Institut de Neurociences (INc), Departament de Biologia Cel.lular, Fisiologia i Immunologia, Bellaterra, Espana. FAU - Rodriguez-Canon, M AU - Rodriguez-Canon M AD - Institut de Neurorehabilitacio Guttmann-UAB, 08916 Badalona, Espana. AD - Institut de Neurociences (INc), Departament de Biologia Cel.lular, Fisiologia i Immunologia, Bellaterra, Espana. AD - Institut de Bioenginyeria de Catalunya (IBEC), Barcelona, Espana. AD - Centro Investigacion Biomedicas en Red Enfermedades Neurodegenerativas (CIBER-NED), Madrid, Espana. FAU - Soriano, I AU - Soriano I AD - Institut de Neurorehabilitacio Guttmann-UAB, 08916 Badalona, Espana. FAU - Garcia, L AU - Garcia L AD - Institut de Neurorehabilitacio Guttmann-UAB, 08916 Badalona, Espana. FAU - Vidal-Samso, J AU - Vidal-Samso J AD - Institut de Neurorehabilitacio Guttmann-UAB, 08916 Badalona, Espana. LA - spa PT - Journal Article PT - Review TT - Estimulacion no invasiva cerebral y medular para la recuperacion motora y funcional tras una lesion medular. PL - Spain TA - Rev Neurol JT - Revista de neurologia JID - 7706841 SB - IM MH - Brain MH - Electric Stimulation Therapy/*methods MH - Humans MH - Recovery of Function MH - Spinal Cord Injuries/*therapy MH - Spinal Cord Stimulation/methods EDAT- 2020/06/06 06:00 MHDA- 2021/06/24 06:00 CRDT- 2020/06/06 06:00 PHST- 2020/06/06 06:00 [entrez] PHST- 2020/06/06 06:00 [pubmed] PHST- 2021/06/24 06:00 [medline] AID - rn2019453 [pii] AID - 10.33588/rn.7012.2019453 [doi] PST - ppublish SO - Rev Neurol. 2020 Jun 16;70(12):461-477. doi: 10.33588/rn.7012.2019453.