PMID- 32502694 OWN - NLM STAT- MEDLINE DCOM- 20201028 LR - 20201028 IS - 1872-8227 (Electronic) IS - 0168-8227 (Linking) VI - 166 DP - 2020 Aug TI - The prevalence of diabetic chronic kidney disease in adult Greek subjects with type 2 diabetes mellitus: A series from hospital-based diabetes clinics. PG - 108243 LID - S0168-8227(20)30493-9 [pii] LID - 10.1016/j.diabres.2020.108243 [doi] AB - AIMS: To examine the prevalence of diabetic chronic kidney disease (DCKD) and its risk factors in adult Greek subjects with type 2 diabetes mellitus (T2DM) in a population from hospital-based diabetes clinics. METHODS: This is a cross-sectional multicentre study based on data collected from Greek hospital-based diabetes clinics from June 2015 to March 2016. DCKD severity was defined according to the Kidney Disease: Improving Global Outcomes (KDIGO) 2012 guidelines. Multivariate analyses assessed the associations between DCKD and its potential risk factors. RESULTS: Among the entire population (n = 1759), the overall prevalence of DCKD was 45% including mild, moderate and severe CKD. Older age, male gender, body-mass index, lack of exercise and diabetes duration were significantly associated with DCKD. CONCLUSIONS: In Greece, DCKD in T2DM is highly prevalent. It is significantly associated with demographic and lifestyle parameters, as well as T2DM complications, suggesting that further efforts to prevent DCKD should be addressed to subjects with specific characteristics. CI - Copyright (c) 2020 Elsevier B.V. All rights reserved. FAU - Migdalis, Ilias N AU - Migdalis IN AD - Second Medical Department and Diabetes Centre, NIMTS Hospital, Monis Petraki 10-12, Athens, Greece. Electronic address: ilianmig@otenet.gr. FAU - Papanas, Nikolaos AU - Papanas N AD - Diabetes Centre, Second Department of Internal Medicine, Democritus University of Thrace, University Hospital of Alexandroupolis, Alexandroupolis, Greece. FAU - Raptis, Athanasios E AU - Raptis AE AD - Second Department of Internal Medicine, Research Institute and Diabetes Center, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece. FAU - Ioannidis, Ioannis M AU - Ioannidis IM AD - Diabetes Centre, First Department of Internal Medicine, General Hospital of Nea Ionia Konstantopoulio-Patision, Athens, Greece. FAU - Sotiropoulos, Alexios E AU - Sotiropoulos AE AD - Diabetes Centre, Third Department of Internal Medicine, General Hospital of Nikaia, Piraeus, Greece. FAU - Dimitriadis, George D AU - Dimitriadis GD AD - Second Department of Internal Medicine, Research Institute and Diabetes Center, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece. CN - Hellenic Diabetic Nephropathy Study (HDNS) Group LA - eng PT - Journal Article DEP - 20200602 PL - Ireland TA - Diabetes Res Clin Pract JT - Diabetes research and clinical practice JID - 8508335 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Cross-Sectional Studies MH - Diabetes Mellitus, Type 2/complications/*epidemiology MH - Diabetic Nephropathies/complications/*epidemiology/pathology MH - Female MH - Greece/epidemiology MH - Hemodialysis Units, Hospital/statistics & numerical data MH - Hospitals/statistics & numerical data MH - Humans MH - Male MH - Middle Aged MH - Prevalence MH - Renal Insufficiency, Chronic/complications/epidemiology/pathology MH - Risk Factors MH - Severity of Illness Index OTO - NOTNLM OT - Complications OT - Diabetic chronic kidney disease OT - Microvascular OT - Nephropathy OT - Prevalence OT - Type 2 diabetes mellitus COIS- Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2020/06/06 06:00 MHDA- 2020/10/29 06:00 CRDT- 2020/06/06 06:00 PHST- 2020/02/05 00:00 [received] PHST- 2020/05/16 00:00 [revised] PHST- 2020/05/23 00:00 [accepted] PHST- 2020/06/06 06:00 [pubmed] PHST- 2020/10/29 06:00 [medline] PHST- 2020/06/06 06:00 [entrez] AID - S0168-8227(20)30493-9 [pii] AID - 10.1016/j.diabres.2020.108243 [doi] PST - ppublish SO - Diabetes Res Clin Pract. 2020 Aug;166:108243. doi: 10.1016/j.diabres.2020.108243. Epub 2020 Jun 2.