PMID- 32515856 OWN - NLM STAT- MEDLINE DCOM- 20210302 LR - 20210615 IS - 1098-240X (Electronic) IS - 0160-6891 (Linking) VI - 43 IP - 4 DP - 2020 Aug TI - Do obesity and low levels of physical activity increase the risk for developing type 2 diabetes mellitus among women with prior gestational diabetes in rural China? PG - 387-395 LID - 10.1002/nur.22043 [doi] AB - Moderate-to-vigorous intensity physical activity (MVPA) and obesity play important roles in the development of type 2 diabetes mellitus (T2DM) among women with prior gestational diabetes mellitus (GDM). Yet, how MVPA affects the risk of developing T2DM among women with prior GDM across the different categories of obesity indicators is unclear. This study aimed to describe the levels of postpartum abnormal glucose tolerance (AGT), obesity indicators (body mass index [BMI] and waist circumference [WC]), and MVPA and to explore the independent effect and joint effect of MVPA and obesity indicators (BMI and WC) on the risk for developing AGT among women with prior GDM in rural China. A total of 425 women with prior GDM were recruited from two county-level hospitals in Western and Eastern Hunan, China. Data were collected with self-reported measurements on sociodemographics and clinical factors as well as postpartum weight-related behaviors (physical activity and dietary intake). The 75-g oral glucose tolerance test, weight, height, and WC were measured on site. Binary logistic regression models and multiplitive interaction models were used to explore the independent and joint associations of BMI and MVPA as well as WC and MVPA on AGT, respectively. One-fifth (20.9%) of the sample women had AGT. The obesity indicators were significantly associated with an increased risk of postpartum AGT, but MVPA was not. In joint effect analyses, larger WC and insufficient MVPA were not significantly associated with increased risk of AGT compared with normal WC and sufficient MVPA (mutually adjusted odds ratio [OR], 1.43; 95% confidence interval [CI], 0.46-4.43; p > .05). In joint effect analyses of MVPA and BMI, the mutually adjusted OR for developing AGT in women who were obese and had insufficient MVPA was 4.49 (95% CI, 1.35-14.92; p < .05) compared with normal weight and sufficient MVPA. Adequate weight management and increased MVPA are warranted for Chinese women with prior GDM to prevent T2DM. CI - (c) 2020 Wiley Periodicals LLC. FAU - Mao, Ping AU - Mao P AD - Department of Nursing, Third Xiangya Hospital, Central South University, Changsha, Hunan, China. FAU - Jiang, Shan AU - Jiang S AD - Department of Clinical Nursing, Xiangya School of Nursing, Central South University, Changsha, Hunan, China. FAU - Guo, Jia AU - Guo J AUID- ORCID: 0000-0002-8304-9947 AD - Department of Clinical Nursing, Xiangya School of Nursing, Central South University, Changsha, Hunan, China. FAU - Long, Qing AU - Long Q AD - Department of Clinical Nursing, Xiangya School of Nursing, Central South University, Changsha, Hunan, China. FAU - Zhang, Honghui AU - Zhang H AD - Department of Hepatobiliary Surgery, Hunan Provincial People's Hospital, Chingsha, Hunan, China. FAU - Chen, Jyu-Lin AU - Chen JL AD - Department of Family Nursing, School of Nursing, University of California, San Francisco, California. LA - eng GR - 17XBQ111/Philosophy and Social Science Foundation of Hunan Province/ GR - 1053320184112/Graduate research and innovation project of central south university of Central South University/ GR - 2018ZK4032/Technology Innovation Guidance Plan Project of Hunan Province/ GR - M01 RR001271/RR/NCRR NIH HHS/United States GR - 2018CX037/Innovation-Driven Project of Central South University/ GR - 16-256/China Medical Board/ PT - Journal Article DEP - 20200609 PL - United States TA - Res Nurs Health JT - Research in nursing & health JID - 7806136 SB - IM MH - Adult MH - China MH - Cross-Sectional Studies MH - Diabetes Mellitus, Type 2/*etiology/*physiopathology MH - Diabetes, Gestational/physiopathology MH - Exercise/*physiology MH - Female MH - Humans MH - Obesity/*complications MH - Postpartum Period MH - Pregnancy MH - Risk Assessment/*statistics & numerical data MH - Rural Population/*statistics & numerical data OTO - NOTNLM OT - body mass index OT - diabetes OT - exercise OT - gestational OT - glucose intolerance OT - obesity OT - waist circumference EDAT- 2020/06/10 06:00 MHDA- 2021/03/03 06:00 CRDT- 2020/06/10 06:00 PHST- 2019/09/24 00:00 [received] PHST- 2020/03/22 00:00 [revised] PHST- 2020/05/19 00:00 [accepted] PHST- 2020/06/10 06:00 [pubmed] PHST- 2021/03/03 06:00 [medline] PHST- 2020/06/10 06:00 [entrez] AID - 10.1002/nur.22043 [doi] PST - ppublish SO - Res Nurs Health. 2020 Aug;43(4):387-395. doi: 10.1002/nur.22043. Epub 2020 Jun 9.