PMID- 32518060
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201022
IS  - 1929-0748 (Print)
IS  - 1929-0748 (Electronic)
IS  - 1929-0748 (Linking)
VI  - 9
IP  - 9
DP  - 2020 Sep 24
TI  - Guided Self-Help Behavioral Activation Intervention for Geriatric Depression: 
      Protocol for Pilot Randomized Controlled Trial.
PG  - e18259
LID - 10.2196/18259 [doi]
LID - e18259
AB  - BACKGROUND: Aging is a social concern. The increased incidence of depression in 
      older populations in China poses a challenge to the health care system. Older 
      adults who are depressed often suffer from a lack of motivation. Behavioral 
      activation treatment, an evidence-based guided self-help treatment, is effective 
      in reducing anhedonia and amotivation in depression; however, the efficacy of 
      guided self-help behavioral activation in older adults with depression is not yet 
      known. OBJECTIVE: The aim of this study is to pilot a self-help guided 
      intervention for the treatment of depression in older adults. METHODS: This study 
      has been designed as a pilot randomized controlled trial with inpatients (n=60; 
      to be randomly allocated 1:1) between the ages of 60 and 70 and who have major 
      depressive disorder. Patients attending clinical psychological clinics at the 
      Mental Health Center of Chongqing will be randomized to either receive guided 
      self-help behavioral activation (intervention) or to be on a 6-week waiting list 
      (control). Participants in the treatment group will receive 6 sessions of guided 
      self-help behavioral activation delivered over the telephone. The waiting list 
      control group will receive the intervention after a period of 6 weeks. Exclusion 
      criteria will be individuals who are at significant risk of harming themselves or 
      others, who have a primary mental health disorder other than depression, or who 
      have an intellectual disability that would hamper their ability to participate in 
      the intervention. Effects of the treatment will be observed using outcomes in 3 
      domains: (1) clinical outcomes (symptom severity, recovery rate), (2) process 
      variables (patient satisfaction, attendance, dropout), and (3) economic outcomes 
      (cost and resource use). We will also examine mediators of outcomes in terms of 
      patient variables (behavioral activation or inhibition motivation). We 
      hypothesize that guided self-help behavioral activation will have a beneficial 
      effect. RESULTS: The study was approved by the research ethics committee of the 
      Mental Health Center of Chongqing in November 2019. As of July 2020, recruitment 
      had not yet begun. Data collection is expected to be completed by December 2020. 
      Data analysis is expected to be completed by June 2021. Results will then be 
      disseminated to patients, to the public, to clinicians, and to researchers 
      through publications in journals and presentations at conferences. CONCLUSIONS: 
      This will be the first study in China to investigate guided self-help 
      interventions for patients who are older adults and who are depressed, a group 
      which is currently underrepresented in mental health research. The intervention 
      is modular and adapted from an empirically supported behavioral activation 
      treatment for depression. The generalizability and broad inclusion criteria are 
      strengths. TRIAL REGISTRATION: Chinese Clinical Trial Register ChiCTR1900026066; 
      http://www.chictr.org.cn/showprojen.aspx?proj=43548. INTERNATIONAL REGISTERED 
      REPORT IDENTIFIER (IRRID): PRR1-10.2196/18259.
CI  - (c)Xiaoxia Wang, Xiaoyan Zhou, Hui Yang. Originally published in JMIR Research 
      Protocols (http://www.researchprotocols.org), 24.09.2020.
FAU - Wang, Xiaoxia
AU  - Wang X
AUID- ORCID: 0000-0001-7707-5607
AD  - Department of Basic Psychology, College of Psychology, Army Medical University, 
      Chongqing, China.
FAU - Zhou, Xiaoyan
AU  - Zhou X
AUID- ORCID: 0000-0002-9087-382X
AD  - Department of Clinical Psychology, Mental Health Center of Chongqing, Chongqing, 
      China.
FAU - Yang, Hui
AU  - Yang H
AUID- ORCID: 0000-0001-8127-9274
AD  - Department of Clinical Psychology, Mental Health Center of Chongqing, Chongqing, 
      China.
LA  - eng
PT  - Journal Article
DEP - 20200924
PL  - Canada
TA  - JMIR Res Protoc
JT  - JMIR research protocols
JID - 101599504
PMC - PMC7545326
OTO - NOTNLM
OT  - behavior activation
OT  - behavior inhibition
OT  - behavior treatment
OT  - clinical
OT  - geriatric depression
OT  - guided self-help
OT  - psychiatry
OT  - psychology
COIS- Conflicts of Interest: None declared.
EDAT- 2020/06/11 06:00
MHDA- 2020/06/11 06:01
PMCR- 2020/09/24
CRDT- 2020/06/11 06:00
PHST- 2020/02/15 00:00 [received]
PHST- 2020/06/09 00:00 [accepted]
PHST- 2020/05/18 00:00 [revised]
PHST- 2020/06/11 06:00 [pubmed]
PHST- 2020/06/11 06:01 [medline]
PHST- 2020/06/11 06:00 [entrez]
PHST- 2020/09/24 00:00 [pmc-release]
AID - v9i9e18259 [pii]
AID - 10.2196/18259 [doi]
PST - epublish
SO  - JMIR Res Protoc. 2020 Sep 24;9(9):e18259. doi: 10.2196/18259.