PMID- 32520813
OWN - NLM
STAT- MEDLINE
DCOM- 20201130
LR  - 20210204
IS  - 1531-7072 (Electronic)
IS  - 1070-5295 (Linking)
VI  - 26
IP  - 4
DP  - 2020 Aug
TI  - The place of extracorporeal life support in cardiogenic shock.
PG  - 424-431
LID - 10.1097/MCC.0000000000000747 [doi]
AB  - PURPOSE OF REVIEW: Temporary circulatory support (TCS) devices are increasingly 
      used as a salvage therapy for patients with refractory cardiogenic shock. The 
      exact place of the different TCS devices in the management of cardiogenic shock 
      patients remains unclear and intensely debated. This article provides an overview 
      on new cardiogenic shock classification, currently available devices, place of 
      TCS in the management of cardiogenic shock patients, and discusses the results of 
      recent case series and trials in this setting. RECENT FINDING: A new 
      classification system for cardiogenic shock has recently been proposed to 
      homogenize definitions of cardiogenic shock and appropriately differentiate 
      patient subsets in clinical trials and registries. Although the routine use of 
      intraaortic balloon pump is no more recommended, other TCS are increasingly used 
      and investigated but many advantages favor the use of venoarterial extracorporeal 
      membrane oxygenation (VA-ECMO) as the first-line TCS. SUMMARY: TCS devices have 
      become the cornerstone of the management of patients with refractory cardiogenic 
      shock. VA-ECMO has emerged as the first-line support system in this setting, with 
      a growing number of accepted indications. Large adequately powered randomized 
      controlled trials are now underway and should help to determine the respective 
      place of different TCS devices in strategies to treat cardiogenic shock patients.
FAU - Pineton de Chambrun, Marc
AU  - Pineton de Chambrun M
AD  - Service de Medecine Intensive-Reanimation, Institut de Cardiologie, APHP Hopital 
      Pitie-Salpetriere.
AD  - Sorbonne Universite, INSERM, UMRS_1166-ICAN, Institute of Cardiometabolism and 
      Nutrition, Paris, France.
FAU - Brechot, Nicolas
AU  - Brechot N
AD  - Service de Medecine Intensive-Reanimation, Institut de Cardiologie, APHP Hopital 
      Pitie-Salpetriere.
AD  - Sorbonne Universite, INSERM, UMRS_1166-ICAN, Institute of Cardiometabolism and 
      Nutrition, Paris, France.
FAU - Combes, Alain
AU  - Combes A
AD  - Service de Medecine Intensive-Reanimation, Institut de Cardiologie, APHP Hopital 
      Pitie-Salpetriere.
AD  - Sorbonne Universite, INSERM, UMRS_1166-ICAN, Institute of Cardiometabolism and 
      Nutrition, Paris, France.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Curr Opin Crit Care
JT  - Current opinion in critical care
JID - 9504454
SB  - IM
MH  - *Cardiovascular System
MH  - *Extracorporeal Membrane Oxygenation
MH  - *Heart-Assist Devices
MH  - Humans
MH  - Intra-Aortic Balloon Pumping
MH  - *Shock, Cardiogenic/therapy
EDAT- 2020/06/11 06:00
MHDA- 2020/12/01 06:00
CRDT- 2020/06/11 06:00
PHST- 2020/06/11 06:00 [pubmed]
PHST- 2020/12/01 06:00 [medline]
PHST- 2020/06/11 06:00 [entrez]
AID - 00075198-202008000-00017 [pii]
AID - 10.1097/MCC.0000000000000747 [doi]
PST - ppublish
SO  - Curr Opin Crit Care. 2020 Aug;26(4):424-431. doi: 10.1097/MCC.0000000000000747.