PMID- 32521094 OWN - NLM STAT- MEDLINE DCOM- 20210514 LR - 20211203 IS - 1522-2594 (Electronic) IS - 0740-3194 (Print) IS - 0740-3194 (Linking) VI - 84 IP - 6 DP - 2020 Dec TI - High spatial resolution whole-neck MR angiography using thin-slab stack-of-stars quiescent interval slice-selective acquisition. PG - 3316-3324 LID - 10.1002/mrm.28339 [doi] AB - PURPOSE: To report a 3D multi-echo thin-slab stack-of-stars (tsSOS) quiescent-interval slice-selective (QISS) strategy for high-resolution magnetic resonance angiography (MRA) of the entire neck in under seven minutes. METHODS: The neck arteries of eight subjects were imaged at 3 Tesla. Multi-echo 3D tsSOS QISS using a FLASH readout was compared with 3D tsSOS FLASH, 2D QISS, 2D TOF, and 3D TOF. A root-mean-square (RMS) combination of echo time images was tested. Evaluation metrics included arterial signal-to-noise ratio (SNR), arterial-to-muscle contrast-to-noise ratio (CNR), and image quality. RESULTS: 3D multi-echo tsSOS QISS using a RMS combination of echo time images increased SNR and CNR by 60% and 63% with respect to the reconstruction obtained with the shortest echo time. 3D tsSOS QISS showed superior CNR with respect to 3D tsSOS FLASH imaging, and more than 3-fold higher SNR and CNR with respect to 2D radial QISS when normalized for voxel size. 3D tsSOS QISS provided good to excellent image quality that exceeded the image quality of 2D QISS, 2D TOF, and 3D TOF (P < .05). CONCLUSION: Whole-neck high-resolution nonenhanced MRA is feasible using 3D tsSOS QISS, and produced image quality that exceeded those of competing nonenhanced MRA protocols at 3 Tesla. CI - (c) 2020 International Society for Magnetic Resonance in Medicine. FAU - Koktzoglou, Ioannis AU - Koktzoglou I AUID- ORCID: 0000-0001-9335-2010 AD - Department of Radiology, NorthShore University HealthSystem, Evanston, IL, USA. AD - Pritzker School of Medicine, University of Chicago, Chicago, IL, USA. FAU - Huang, Rong AU - Huang R AD - Department of Radiology, NorthShore University HealthSystem, Evanston, IL, USA. FAU - Ong, Archie L AU - Ong AL AD - Pritzker School of Medicine, University of Chicago, Chicago, IL, USA. AD - Department of Neurology, NorthShore University HealthSystem, Evanston, IL, USA. FAU - Aouad, Pascale J AU - Aouad PJ AD - Department of Radiology, NorthShore University HealthSystem, Evanston, IL, USA. AD - Northwestern University Feinberg School of Medicine, Chicago, IL, USA. FAU - Walker, Matthew T AU - Walker MT AD - Department of Radiology, NorthShore University HealthSystem, Evanston, IL, USA. AD - Pritzker School of Medicine, University of Chicago, Chicago, IL, USA. FAU - Edelman, Robert R AU - Edelman RR AUID- ORCID: 0000-0002-0013-8822 AD - Department of Radiology, NorthShore University HealthSystem, Evanston, IL, USA. AD - Northwestern University Feinberg School of Medicine, Chicago, IL, USA. LA - eng GR - R01 EB027475/EB/NIBIB NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural DEP - 20200610 PL - United States TA - Magn Reson Med JT - Magnetic resonance in medicine JID - 8505245 SB - IM MH - Arteries MH - Humans MH - Imaging, Three-Dimensional MH - *Magnetic Resonance Angiography MH - *Neck MH - Reproducibility of Results PMC - PMC7722209 MID - NIHMS1627958 OTO - NOTNLM OT - 3D QISS OT - MRA OT - carotid OT - neck OT - stack of stars OT - vertebral EDAT- 2020/06/11 06:00 MHDA- 2021/05/15 06:00 PMCR- 2021/12/01 CRDT- 2020/06/11 06:00 PHST- 2020/02/19 00:00 [received] PHST- 2020/05/01 00:00 [revised] PHST- 2020/05/03 00:00 [accepted] PHST- 2020/06/11 06:00 [pubmed] PHST- 2021/05/15 06:00 [medline] PHST- 2020/06/11 06:00 [entrez] PHST- 2021/12/01 00:00 [pmc-release] AID - 10.1002/mrm.28339 [doi] PST - ppublish SO - Magn Reson Med. 2020 Dec;84(6):3316-3324. doi: 10.1002/mrm.28339. Epub 2020 Jun 10.