PMID- 32532328
OWN - NLM
STAT- MEDLINE
DCOM- 20210112
LR  - 20210112
IS  - 2045-709X (Electronic)
IS  - 2045-709X (Linking)
VI  - 28
IP  - 1
DP  - 2020 Jun 12
TI  - Pressure pain threshold and temporal summation in adults with episodic and 
      persistent low back pain trajectories: a secondary analysis at baseline and after 
      lumbar manipulation or sham.
PG  - 36
LID - 10.1186/s12998-020-00326-5 [doi]
LID - 36
AB  - BACKGROUND: People with chronic low back pain (LBP) typically have increased pain 
      sensitivity compared to healthy controls, however its unknown if pain sensitivity 
      differs based on LBP trajectory at baseline or after manual therapy 
      interventions. We aimed to compare baseline pressure pain threshold (PPT) and 
      temporal summation (TS) between people without LBP, with episodic LBP, and with 
      persistent LBP, and to compare changes over time in PPT and TS after a lumbar 
      spinal manipulation or sham manipulation in those with LBP. METHODS: Participants 
      were aged 18-59, with or without LBP. Those with LBP were categorised as having 
      either episodic or persistent LBP. PPT and TS were tested at baseline. LBP 
      participants then received a lumbar spinal manipulation or sham, after which PPT 
      and TS were re-tested three times over 30 min. Generalised linear mixed models 
      were used to analyse data. RESULTS: One hundred participants (49 female) were 
      included and analysed. There were 20 non-LBP participants (mean age 31 yrs), 23 
      episodic LBP (mean age 35 yrs), and 57 persistent LBP (mean age 37 yrs). There 
      were no significant differences in PPT or TS between groups at baseline. There 
      was a non-significant pattern of lower PPT (higher sensitivity) from the non-LBP 
      group to the persistent LBP group at baseline, and high variability. Changes in 
      PPT and TS after the interventions did not differ between the two LBP groups. 
      DISCUSSION: We found no differences between people with no LBP, episodic LBP, or 
      persistent LBP in baseline PPT or TS. Changes in PPT and TS following a lumbar 
      manual therapy intervention do not appear to differ between LBP trajectories. 
      TRIAL REGISTRATION: The trial was prospectively registered with ANZCTR 
      (ACTRN12617001094369).
FAU - Aspinall, Sasha L
AU  - Aspinall SL
AUID- ORCID: 0000-0003-1019-5940
AD  - College of Science, Health, Engineering and Education, Murdoch University, 90 
      South St, Murdoch, WA, 6150, Australia. sasha.aspinall@murdoch.edu.au.
FAU - Jacques, Angela
AU  - Jacques A
AD  - College of Science, Health, Engineering and Education, Murdoch University, 90 
      South St, Murdoch, WA, 6150, Australia.
FAU - Leboeuf-Yde, Charlotte
AU  - Leboeuf-Yde C
AD  - College of Science, Health, Engineering and Education, Murdoch University, 90 
      South St, Murdoch, WA, 6150, Australia.
AD  - Institute of Regional Health Research, University of Southern Denmark, J. B. 
      Winslows Vej 19, 3, 5000, Odense C, Denmark.
FAU - Etherington, Sarah J
AU  - Etherington SJ
AD  - College of Science, Health, Engineering and Education, Murdoch University, 90 
      South St, Murdoch, WA, 6150, Australia.
FAU - Walker, Bruce F
AU  - Walker BF
AD  - College of Science, Health, Engineering and Education, Murdoch University, 90 
      South St, Murdoch, WA, 6150, Australia.
LA  - eng
SI  - ANZCTR/ACTRN12617001094369
PT  - Comparative Study
PT  - Journal Article
PT  - Observational Study
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20200612
PL  - England
TA  - Chiropr Man Therap
JT  - Chiropractic & manual therapies
JID - 101551481
RN  - 0 (Placebos)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Female
MH  - Humans
MH  - Low Back Pain/*therapy
MH  - Male
MH  - Manipulation, Spinal/*methods
MH  - Middle Aged
MH  - Nervous System Physiological Phenomena
MH  - *Pain Threshold
MH  - Placebos
MH  - Surveys and Questionnaires
MH  - Young Adult
PMC - PMC7291433
OTO - NOTNLM
OT  - Hyperalgesia
OT  - Low back pain
OT  - Pressure pain threshold, temporal summation
OT  - Quantitative sensory testing
OT  - Sensitisation
OT  - Sensitization
OT  - Spinal manipulation
OT  - Trajectories
COIS- BW is Editor in Chief and CLY is Senior Editorial Advisor of Chiropractic & 
      Manual Therapies. Both played no part in the review of this submission and were 
      blinded to the process. SA, AJ and SE declare that they have no competing 
      interests.
EDAT- 2020/06/14 06:00
MHDA- 2021/01/13 06:00
PMCR- 2020/06/12
CRDT- 2020/06/14 06:00
PHST- 2019/12/12 00:00 [received]
PHST- 2020/06/04 00:00 [accepted]
PHST- 2020/06/14 06:00 [entrez]
PHST- 2020/06/14 06:00 [pubmed]
PHST- 2021/01/13 06:00 [medline]
PHST- 2020/06/12 00:00 [pmc-release]
AID - 10.1186/s12998-020-00326-5 [pii]
AID - 326 [pii]
AID - 10.1186/s12998-020-00326-5 [doi]
PST - epublish
SO  - Chiropr Man Therap. 2020 Jun 12;28(1):36. doi: 10.1186/s12998-020-00326-5.