PMID- 32533365 OWN - NLM STAT- MEDLINE DCOM- 20210114 LR - 20210903 IS - 2196-5412 (Electronic) IS - 2196-5412 (Linking) VI - 7 IP - 3 DP - 2020 Sep TI - A Scoping Review of Non-Occupational Exposures to Environmental Pollutants and Adult Depression, Anxiety, and Suicide. PG - 256-271 LID - 10.1007/s40572-020-00280-7 [doi] AB - PURPOSE OF REVIEW: Despite a call for better understanding of the role of environmental pollutant influences on mental health and the tremendous public health burden of mental health, this issue receives far less attention than many other effects of pollutants. Here we summarize the body of literature on non-occupational environmental pollutant exposures and adult depression, anxiety, and suicide-in PubMed, Embase, Web of Science, and PsychINFO through the end of year 2018. RECENT FINDINGS: One hundred twelve articles met our criteria for further review. Of these, we found 88 articles on depression, 33 on anxiety, and 22 on suicide (31 articles covered multiple outcomes). The earliest article was published in 1976, and the most frequent exposure of interest was air pollution (n = 33), followed by secondhand smoke (n = 20), metals (n = 18), noise (n = 17), and pesticides (n = 10). Other exposures studied less frequently included radiation, magnetic fields, persistent organic pollutants (POPs), volatile organic compounds, solvents, and reactive sulfur compounds. The current literature, although limited, clearly suggests many kinds of environmental exposures may be risk factors for depression, anxiety, and suicide. For several pollutants, important limitations exist with many of the studies. Gaps in the body of research include a need for more longitudinal, life-course studies, studies that can measure cumulative exposures as well as shorter-term exposures, studies that reduce the possibility of reverse causation, and mechanistic studies focused on neurotoxic exposures. FAU - Dickerson, Aisha S AU - Dickerson AS AD - Departments of Epidemiology and Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA. FAU - Wu, Alexander C AU - Wu AC AD - Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA. FAU - Liew, Zeyan AU - Liew Z AD - Department of Environmental Health Sciences, Center for Perinatal Pediatric, and Environmental Epidemiology, Yale School of Public Health, New Haven, CT, 06510, USA. FAU - Weisskopf, Marc AU - Weisskopf M AD - Departments of Epidemiology and Environmental Health, Harvard T.H. Chan School of Public Health, 665 Huntington Avenue, Building 1, Suite 1402, Boston, MA, 02115, USA. mweissko@hsph.harvard.edu. LA - eng GR - T42 OH008416/OH/NIOSH CDC HHS/United States GR - P30 ES000002/ES/NIEHS NIH HHS/United States GR - K99 ES026729/ES/NIEHS NIH HHS/United States GR - T32 ES007069/ES/NIEHS NIH HHS/United States GR - R00 ES026729/ES/NIEHS NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, U.S. Gov't, P.H.S. PT - Review PL - Switzerland TA - Curr Environ Health Rep JT - Current environmental health reports JID - 101629387 RN - 0 (Air Pollutants) RN - 0 (Environmental Pollutants) RN - 0 (Pesticides) RN - 0 (Volatile Organic Compounds) SB - IM MH - Adult MH - Air Pollutants/toxicity MH - Air Pollution/adverse effects MH - Anxiety/*chemically induced MH - Depression/*chemically induced MH - Environmental Exposure/*adverse effects MH - Environmental Pollutants/*toxicity MH - Female MH - Humans MH - Male MH - Mental Disorders/chemically induced MH - Mental Health MH - Pesticides/toxicity MH - Public Health MH - Risk Factors MH - Suicide/*statistics & numerical data MH - Volatile Organic Compounds/toxicity PMC - PMC7483936 MID - NIHMS1603789 OTO - NOTNLM OT - Anxiety OT - Depression OT - Environmental pollutants OT - Mental health OT - Suicide COIS- Conflict of Interest Aisha S. Dickerson, Alexander C. Wu, Zeyan Liew, and Marc G. Weisskopf declare that they have no conflicts of interest. EDAT- 2020/06/14 06:00 MHDA- 2021/01/15 06:00 PMCR- 2021/09/01 CRDT- 2020/06/14 06:00 PHST- 2020/06/14 06:00 [pubmed] PHST- 2021/01/15 06:00 [medline] PHST- 2020/06/14 06:00 [entrez] PHST- 2021/09/01 00:00 [pmc-release] AID - 10.1007/s40572-020-00280-7 [pii] AID - 10.1007/s40572-020-00280-7 [doi] PST - ppublish SO - Curr Environ Health Rep. 2020 Sep;7(3):256-271. doi: 10.1007/s40572-020-00280-7.