PMID- 32534150
OWN - NLM
STAT- MEDLINE
DCOM- 20210514
LR  - 20210514
IS  - 2213-2201 (Electronic)
VI  - 8
IP  - 9
DP  - 2020 Oct
TI  - Association Between Self-Reported Dental Hygiene Practices and Dental 
      Procedure-Related Recurrent Angioedema Attacks in HAE Subjects: A Multicenter 
      Survey.
PG  - 3162-3169.e5
LID - S2213-2198(20)30582-1 [pii]
LID - 10.1016/j.jaip.2020.05.041 [doi]
AB  - BACKGROUND: Hereditary angioedema (HAE) symptoms may be triggered by dental 
      procedures, thereby complicating dental care in individuals affected by 
      the condition. OBJECTIVE: This study investigated the self-perceived dental care 
      needs, perceived susceptibility to acute angioedema (AE) attacks after dental 
      procedures, and dental care behavior of patients with HAE. METHODS: A 
      self-administered semistructured web-based questionnaire was distributed to 250 
      adult patients with HAE (type 1 or 2; 88% type 1) and 256 matched non-HAE 
      controls. Data were analyzed using stratified chi(2) tests, logistic regression, 
      and classification trees. RESULTS: A total of 46.4% of HAE versus 55.5% of 
      control patients had dental visits within 6 months (P = .04). Dental insurance 
      was a barrier to seeking routine dental visits among both groups. However, 
      significantly fewer patients with HAE had routine dental visits within 6 months 
      despite having dental insurance compared with control patients (48% vs 60%, 
      P = .01). Within the HAE group, a significantly greater number of patients with 
      dental visits at intervals greater than 6 months had a history of recurrent 
      postprocedural AE attacks (odds ratio [OR]: 3.9 [1.7, 8.8], P = .0005) and used 
      antibacterial toothpaste more frequently than those without recurrent AE attacks 
      (OR: 4.7 [1.5, 15.4], P = .005). CONCLUSIONS: These data support the hypothesis 
      that patients with HAE who are predisposed to having AE episodes in response to 
      medical or physical trauma visit the dentist less and engage in specific oral 
      hygiene practices more frequently than matched control patients and patients with 
      HAE who reported that they were less likely to swell after a dental procedure.
CI  - Copyright (c) 2020 American Academy of Allergy, Asthma & Immunology. Published by 
      Elsevier Inc. All rights reserved.
FAU - Singh, Umesh
AU  - Singh U
AD  - Division of Immunology/Allergy, Department of Internal Medicine, University of 
      Cincinnati College of Medicine, Cincinnati, Ohio.
FAU - Lumry, William R
AU  - Lumry WR
AD  - Allergy and Asthma Research Associates Research Center, Dallas, Texas.
FAU - Busse, Paula
AU  - Busse P
AD  - Division of Clinical Immunology, Mount Sinai, New York, NY.
FAU - Wedner, H James
AU  - Wedner HJ
AD  - Allergy and Immunology, Washington University School of Medicine, St. Louis, Mo.
FAU - Banerji, Aleena
AU  - Banerji A
AD  - Division of Rheumatology, Department of Allergy & Immunology, Massachusetts 
      General Hospital, Boston, Mass.
FAU - Craig, Timothy J
AU  - Craig TJ
AD  - Department of Medicine and Pediatrics, Penn State University, Hershey, Pa.
FAU - Li, H Henry
AU  - Li HH
AD  - Institute for Asthma and Allergy, PC, Chevy Chase, Md.
FAU - Tachdjian, Raffi
AU  - Tachdjian R
AD  - Division of Allergy and Immunology, UCLA School of Medicine, Los Angeles, Calif.
FAU - Jacobs, Joshua S
AU  - Jacobs JS
AD  - Allergy and Asthma Clinical Research, Inc., Walnut Creek, Calif.
FAU - Riedl, Marc A
AU  - Riedl MA
AD  - Divison of Rheumatology, Allergy & Immunology, University of California, San 
      Diego, La Jolla, Calif.
FAU - Davis-Lorton, Mark
AU  - Davis-Lorton M
AD  - Department of Medicine, Winthrop University Hospital, Mineola, NY.
FAU - Christiansen, Sandra C
AU  - Christiansen SC
AD  - Divison of Rheumatology, Allergy & Immunology, University of California, San 
      Diego, La Jolla, Calif.
FAU - Zuraw, Bruce L
AU  - Zuraw BL
AD  - Divison of Rheumatology, Allergy & Immunology, University of California, San 
      Diego, La Jolla, Calif.
FAU - Bernstein, Jonathan A
AU  - Bernstein JA
AD  - Division of Immunology/Allergy, Department of Internal Medicine, University of 
      Cincinnati College of Medicine, Cincinnati, Ohio. Electronic address: 
      bernstja@ucmail.uc.edu.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20200610
PL  - United States
TA  - J Allergy Clin Immunol Pract
JT  - The journal of allergy and clinical immunology. In practice
JID - 101597220
RN  - 0 (Complement C1 Inhibitor Protein)
SB  - IM
MH  - Adult
MH  - *Angioedema
MH  - *Angioedemas, Hereditary/epidemiology
MH  - Complement C1 Inhibitor Protein
MH  - Humans
MH  - Oral Hygiene
MH  - Self Report
MH  - Surveys and Questionnaires
OTO - NOTNLM
OT  - Dental hygiene
OT  - Health belief model
OT  - Hereditary angioedema
OT  - Postdental procedure angioedema attacks
OT  - Questionnaire survey
OT  - Routine dental visit
OT  - Teeth brushing frequency
EDAT- 2020/06/14 06:00
MHDA- 2021/05/15 06:00
CRDT- 2020/06/14 06:00
PHST- 2019/10/03 00:00 [received]
PHST- 2020/05/01 00:00 [revised]
PHST- 2020/05/20 00:00 [accepted]
PHST- 2020/06/14 06:00 [pubmed]
PHST- 2021/05/15 06:00 [medline]
PHST- 2020/06/14 06:00 [entrez]
AID - S2213-2198(20)30582-1 [pii]
AID - 10.1016/j.jaip.2020.05.041 [doi]
PST - ppublish
SO  - J Allergy Clin Immunol Pract. 2020 Oct;8(9):3162-3169.e5. doi: 
      10.1016/j.jaip.2020.05.041. Epub 2020 Jun 10.