PMID- 32542169 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200928 IS - 2168-8184 (Print) IS - 2168-8184 (Electronic) IS - 2168-8184 (Linking) VI - 12 IP - 5 DP - 2020 May 14 TI - Biloma: A Rare Manifestation of Spontaneous Bile Leak. PG - e8116 LID - 10.7759/cureus.8116 [doi] LID - e8116 AB - A biloma is an intrahepatic or extrahepatic encapsulated collection of bile outside of the biliary tree and within the abdominal cavity. Hepatobiliary interventions and laparoscopic cholecystectomy are the most common etiologies of biloma followed by abdominal trauma, choledocholithiasis, and biliary dilation secondary to biliary stricture. We report a case of a 91-year-old female who presented to the emergency room with an acute onset of epigastric and right upper quadrant sharp pain for one day that radiated to the back, and was associated with two to three episodes of vomiting. Initial abdominal imaging including CT scan, ultrasound and magnetic resonance cholangiopancreatography (MRCP) of the abdomen and pelvis revealed a distended gallbladder with wall thickening, but without evidence of pancreatitis or gallstones. Hepatobiliary iminodiacetic acid (HIDA) scan findings were consistent with extrahepatic biliary leakage into the peritoneum. A cholangiogram demonstrated a perihepatic biloma. A combined approach using fluoroscopic-guided biloma drainage and endoscopic retrograde cholangiopancreatography (ERCP)-guided biliary stent placement across the site of the biliary leak resulted in the complete resolution of symptoms. Biloma should be included in the differential diagnosis of right upper quadrant abdominal pain. A high index of clinical suspicion is required for early diagnosis and treatment. CI - Copyright (c) 2020, Yousaf et al. FAU - Yousaf, Muhammad N AU - Yousaf MN AD - Internal Medicine, MedStar Union Memorial Hospital, Baltimore, USA. AD - Internal Medicine, MedStar Franklin Square Medical Center, Baltimore, USA. AD - Internal Medicine, MedStar Good Samaritan Hospital, Baltimore, USA. AD - Section of Digestive Diseases, Yale University School of Medicine, New Haven, USA. FAU - D'Souza, Rowena G AU - D'Souza RG AD - Medicine, MedStar Union Memorial Hospital, Baltimore, USA. FAU - Chaudhary, Fizah AU - Chaudhary F AD - Internal Medicine, MedStar Union Memorial Hospital, Baltimore, USA. FAU - Ehsan, Hamid AU - Ehsan H AD - Internal Medicine, MedStar Union Memorial Hospital, Baltimore, USA. FAU - Sittambalam, Charmian AU - Sittambalam C AD - Geriatrics, MedStar Franklin Square Medical Center, Baltimore, USA. LA - eng PT - Case Reports DEP - 20200514 PL - United States TA - Cureus JT - Cureus JID - 101596737 PMC - PMC7292700 OTO - NOTNLM OT - : biloma OT - ercp OT - hepatobiliary interventions OT - pancreatitis OT - percutaneous drainage OT - spontaneous bile leak COIS- The authors have declared that no competing interests exist. EDAT- 2020/06/17 06:00 MHDA- 2020/06/17 06:01 PMCR- 2020/05/14 CRDT- 2020/06/17 06:00 PHST- 2020/06/17 06:00 [entrez] PHST- 2020/06/17 06:00 [pubmed] PHST- 2020/06/17 06:01 [medline] PHST- 2020/05/14 00:00 [pmc-release] AID - 10.7759/cureus.8116 [doi] PST - epublish SO - Cureus. 2020 May 14;12(5):e8116. doi: 10.7759/cureus.8116.