PMID- 32557424
OWN - NLM
STAT- MEDLINE
DCOM- 20201030
LR  - 20210701
IS  - 1833-3516 (Print)
IS  - 2209-1491 (Electronic)
IS  - 1833-3516 (Linking)
VI  - 50
IP  - 2
DP  - 2020 Jun 30
TI  - Sudden death after oxygen toxicity seizure during hyperbaric oxygen treatment: 
      Case report.
PG  - 185-188
LID - 10.28920/dhm50.2.185-188 [doi]
AB  - Acute cerebral oxygen toxicity (ACOT) is a known side effect of hyperbaric oxygen 
      treatment (HBOT), which can cause generalised seizures. Fortunately, it has a low 
      incidence and is rarely harmful. Nevertheless, we present a case of a 37 year-old 
      patient with morbid obesity who died unexpectedly after an oxygen toxicity 
      seizure in the hyperbaric chamber. Considering possible causes, physiologic 
      changes in obesity and obesity hypoventilation syndrome may increase the risk of 
      ACOT. Obesity, especially in extreme cases, may hinder emergency procedures, both 
      in- and outside of a hyperbaric chamber. Physicians in the hyperbaric field 
      should be aware of the possibility of a fatal outcome after ACOT through the 
      described mechanisms and take appropriate preventative measures. Basic airway 
      management skills are strongly advised for involved physicians, especially when 
      specialised personnel and equipment are not immediately available.
CI  - Copyright: This article is the copyright of the authors who grant Diving and 
      Hyperbaric Medicine a non-exclusive licence to publish the article in electronic 
      and other forms.
FAU - Lalieu, Rutger C
AU  - Lalieu RC
AD  - Hyperbaar Geneeskundig Centrum, Rijswijk, the Netherlands.
AD  - Amsterdam University Medical Centres, Department of Anaesthesiology, Amsterdam, 
      the Netherlands.
AD  - Corresponding author: Rutger C Lalieu, Treubstraat 5A, 2288 EG Rijswijk, the 
      Netherlands, r.lalieu@hgcrijswijk.nl.
FAU - Bol Raap, Rene D
AU  - Bol Raap RD
AD  - Hyperbaar Geneeskundig Centrum, Rijswijk, the Netherlands.
FAU - Dubois, Emile Fl
AU  - Dubois EF
AD  - Hyperbaar Geneeskundig Centrum, Rijswijk, the Netherlands.
FAU - van Hulst, Rob A
AU  - van Hulst RA
AD  - Amsterdam University Medical Centres, Department of Anaesthesiology, Amsterdam, 
      the Netherlands.
AD  - Amsterdam University Medical Centres, Department of Surgery, Hyperbaric Dept., 
      Amsterdam, the Netherlands.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Australia
TA  - Diving Hyperb Med
JT  - Diving and hyperbaric medicine
JID - 101282742
RN  - S88TT14065 (Oxygen)
SB  - IM
MH  - Adult
MH  - *Death, Sudden/etiology
MH  - Humans
MH  - *Hyperbaric Oxygenation/adverse effects
MH  - Obesity, Morbid
MH  - *Oxygen/adverse effects
MH  - Seizures/chemically induced/therapy
PMC - PMC7481105
OTO - NOTNLM
OT  - Case reports
OT  - Deaths
OT  - Hyperbaric oxygen treatment
OT  - Obesity
OT  - Risk management
OT  - Side effects
COIS- Conflict of interest and funding: nil
EDAT- 2020/06/20 06:00
MHDA- 2020/10/31 06:00
PMCR- 2021/06/30
CRDT- 2020/06/20 06:00
PHST- 2019/12/03 00:00 [received]
PHST- 2020/03/18 00:00 [accepted]
PHST- 2020/06/20 06:00 [entrez]
PHST- 2020/06/20 06:00 [pubmed]
PHST- 2020/10/31 06:00 [medline]
PHST- 2021/06/30 00:00 [pmc-release]
AID - 10.28920/dhm50.2.185-188 [doi]
PST - ppublish
SO  - Diving Hyperb Med. 2020 Jun 30;50(2):185-188. doi: 10.28920/dhm50.2.185-188.