PMID- 32559008
OWN - NLM
STAT- MEDLINE
DCOM- 20210625
LR  - 20210625
IS  - 1468-1331 (Electronic)
IS  - 1351-5101 (Linking)
VI  - 27
IP  - 11
DP  - 2020 Nov
TI  - A comparative evaluation of different neuromyelitis optica spectrum disorder sets 
      of criteria.
PG  - 2250-2256
LID - 10.1111/ene.14414 [doi]
AB  - BACKGROUND AND PURPOSE: Three different sets of criteria have been proposed for 
      the diagnosis of neuromyelitis optica spectrum disorder (NMOSD). The objective 
      was to compare the specificity, sensitivity and diagnostic accuracy of the three 
      different sets of NMOSD criteria in patients presenting with inflammatory 
      disorders of the central nervous system suggestive of NMOSD. METHODS: For 236 
      suspected NMOSD patients referred for serum aquaporin-4 immunoglobulin G antibody 
      (AQP4-IgG) testing between 2012 and 2014, the three sets of NMOSD criteria [1999, 
      2006 NMO criteria and 2015 International Panel for NMO Diagnosis (IPND) criteria] 
      were applied and compared to the final diagnosis. RESULTS: Seventy-six patients 
      fulfilled at least one set of criteria and 28 patients fulfilled all NMOSD sets 
      of criteria. The final diagnosis was NMOSD in 66 cases, multiple sclerosis 
      according to the MacDonald 2010 criteria in 85 cases and another diagnosis in 85 
      cases. The 2006 NMO criteria have the highest specificity (99%) and the 2015 IPND 
      NMOSD criteria the highest sensitivity (97%). For the 1999, 2006 and 2015 IPND 
      NMOSD criteria, the accuracy was respectively 82%, 87% and 97%. CONCLUSIONS: Our 
      study highlights the limitations of the first set of criteria that include the 
      optico-spinal form of multiple sclerosis. The accuracy of NMOSD diagnostic 
      criteria improved from 1999 to 2015. It confirms the increased performance of the 
      last set of criteria which covers a larger spectrum of clinical presentation. 
      This study raises some concerns for classifying patients with seronegative 
      transverse myelitis or optic neuritis, and myelin oligodendrocyte glycoprotein 
      (MOG) antibody- associated disease.
CI  - (c) 2020 European Academy of Neurology.
FAU - Papeix, C
AU  - Papeix C
AUID- ORCID: 0000-0003-4074-6125
AD  - Assistance Publique Hopitaux de Paris (APHP), Sorbonne Universite, Department of 
      Neurology, Centre de Reference des Maladies Inflammatoires Rares du Cerveau et de 
      la Moelle (MIRCEM), Groupe Hospitalier Pitie Salpetriere, Paris, France.
FAU - Beigneux, Y
AU  - Beigneux Y
AD  - Assistance Publique Hopitaux de Paris (APHP), Sorbonne Universite, Department of 
      Neurology, Centre de Reference des Maladies Inflammatoires Rares du Cerveau et de 
      la Moelle (MIRCEM), Groupe Hospitalier Pitie Salpetriere, Paris, France.
FAU - Maillart, E
AU  - Maillart E
AD  - Assistance Publique Hopitaux de Paris (APHP), Sorbonne Universite, Department of 
      Neurology, Centre de Reference des Maladies Inflammatoires Rares du Cerveau et de 
      la Moelle (MIRCEM), Groupe Hospitalier Pitie Salpetriere, Paris, France.
FAU - de Seze, J
AU  - de Seze J
AD  - Department of Neurology, University Hospital of Strasbourg, Centre Investigation 
      Clinique (CIC) de Strasbourg, INSERM 1434, Strasbourg, France.
FAU - Lubetzki, C
AU  - Lubetzki C
AD  - Assistance Publique Hopitaux de Paris (APHP), Sorbonne Universite, Department of 
      Neurology, Centre de Reference des Maladies Inflammatoires Rares du Cerveau et de 
      la Moelle (MIRCEM), Groupe Hospitalier Pitie Salpetriere, Paris, France.
FAU - Vukusic, S
AU  - Vukusic S
AD  - Service de Neurologie, Sclerose en Plaques, Pathologies de la Myeline et 
      Neuro-inflammation, Centre de Reference des Maladies Inflammatoires Rares du 
      Cerveau et de la Moelle (MIRCEM), Hopital Neurologique Pierre Wertheimer, 
      Hospices Civils de Lyon, Lyon/Bron, France.
AD  - Centre des Neurosciences de Lyon, Observatoire Francais de la Sclerose en 
      Plaques, INSERM 1028 et CNRS UMR5292, Lyon, France.
AD  - Universite Claude Bernard Lyon 1, Faculte de Medecine Lyon Est, Lyon, France.
FAU - Collongues, N
AU  - Collongues N
AUID- ORCID: 0000-0002-3683-5582
AD  - Department of Neurology, University Hospital of Strasbourg, Centre Investigation 
      Clinique (CIC) de Strasbourg, INSERM 1434, Strasbourg, France.
FAU - Marignier, R
AU  - Marignier R
AD  - Service de Neurologie, Sclerose en Plaques, Pathologies de la Myeline et 
      Neuro-inflammation, Centre de Reference des Maladies Inflammatoires Rares du 
      Cerveau et de la Moelle (MIRCEM), Hopital Neurologique Pierre Wertheimer, 
      Hospices Civils de Lyon, Lyon/Bron, France.
AD  - Centre des Neurosciences de Lyon, Observatoire Francais de la Sclerose en 
      Plaques, INSERM 1028 et CNRS UMR5292, Lyon, France.
AD  - Universite Claude Bernard Lyon 1, Faculte de Medecine Lyon Est, Lyon, France.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20200728
PL  - England
TA  - Eur J Neurol
JT  - European journal of neurology
JID - 9506311
RN  - 0 (Aquaporin 4)
RN  - 0 (Autoantibodies)
RN  - 0 (Immunoglobulin G)
RN  - 0 (Myelin-Oligodendrocyte Glycoprotein)
SB  - IM
MH  - Aquaporin 4
MH  - Autoantibodies
MH  - Humans
MH  - Immunoglobulin G
MH  - *Multiple Sclerosis
MH  - Myelin-Oligodendrocyte Glycoprotein
MH  - *Neuromyelitis Optica/diagnosis
OTO - NOTNLM
OT  - criteria
OT  - multiple sclerosis
OT  - neuromyelitis optica
EDAT- 2020/06/20 06:00
MHDA- 2021/06/29 06:00
CRDT- 2020/06/20 06:00
PHST- 2020/04/07 00:00 [received]
PHST- 2020/06/16 00:00 [accepted]
PHST- 2020/06/20 06:00 [pubmed]
PHST- 2021/06/29 06:00 [medline]
PHST- 2020/06/20 06:00 [entrez]
AID - 10.1111/ene.14414 [doi]
PST - ppublish
SO  - Eur J Neurol. 2020 Nov;27(11):2250-2256. doi: 10.1111/ene.14414. Epub 2020 Jul 
      28.