PMID- 32562100 OWN - NLM STAT- MEDLINE DCOM- 20210127 LR - 20210127 IS - 1534-3170 (Electronic) IS - 1523-3782 (Linking) VI - 22 IP - 8 DP - 2020 Jun 19 TI - Machine Learning-Based Segmentation of Left Ventricular Myocardial Fibrosis from Magnetic Resonance Imaging. PG - 65 LID - 10.1007/s11886-020-01321-1 [doi] AB - PURPOSE OF REVIEW: Myocardial fibrosis (MF) arises due to myocardial infarction and numerous cardiac diseases. MF may lead to several heart disorders, such as heart failure, arrhythmias, and ischemia. Cardiac magnetic resonance (CMR) imaging techniques, such as late gadolinium enhancement (LGE) CMR, enable non-invasive assessment of MF in the left ventricle (LV). Manual assessment of MF on CMR is a tedious and time-consuming task that is subject to high observer variability. Automated segmentation and quantification of MF is important for risk stratification and treatment planning in patients with heart disorders. This article aims to review the machine learning (ML)-based methodologies developed for MF quantification in the LV using CMR images. RECENT FINDINGS: With the availability of relatively large labeled datasets supervised learning methods based on both conventional ML and state-of-the-art deep learning (DL) methods have been successfully applied for automated segmentation of MF. The incorporation of ML algorithms into imaging techniques such as 3D LGE CMR permits fast characterization of MF on CMR imaging and may enhance the diagnosis and prognosis of patients with heart disorders. Concurrently, the studies using cine CMR images have revealed that accurate segmentation of MF on non-contrast CMR imaging might be possible. The application of ML/DL tools in CMR image interpretation is likely to result in accurate and efficient quantification of MF. FAU - Zabihollahy, Fatemeh AU - Zabihollahy F AUID- ORCID: 0000-0003-3362-1009 AD - Department of Systems and Computer Engineering, Carleton University, Ottawa, ON, Canada. fatemehzabihollahy@cmail.carleton.ca. FAU - Rajan, S AU - Rajan S AD - Department of Systems and Computer Engineering, Carleton University, Ottawa, ON, Canada. FAU - Ukwatta, E AU - Ukwatta E AD - School of Engineering, University of Guelph, Guelph, ON, Canada. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review DEP - 20200619 PL - United States TA - Curr Cardiol Rep JT - Current cardiology reports JID - 100888969 RN - 0 (Contrast Media) RN - AU0V1LM3JT (Gadolinium) SB - IM MH - *Contrast Media MH - Fibrosis MH - Gadolinium MH - *Heart Ventricles/pathology MH - Humans MH - Machine Learning MH - Magnetic Resonance Imaging MH - Magnetic Resonance Imaging, Cine MH - Myocardium/pathology MH - Predictive Value of Tests OTO - NOTNLM OT - Cardiac magnetic resonance imaging OT - Deep learning OT - Late gadolinium enhancement OT - Machine learning OT - Myocardial fibrosis EDAT- 2020/06/21 06:00 MHDA- 2021/01/28 06:00 CRDT- 2020/06/21 06:00 PHST- 2020/06/21 06:00 [entrez] PHST- 2020/06/21 06:00 [pubmed] PHST- 2021/01/28 06:00 [medline] AID - 10.1007/s11886-020-01321-1 [pii] AID - 10.1007/s11886-020-01321-1 [doi] PST - epublish SO - Curr Cardiol Rep. 2020 Jun 19;22(8):65. doi: 10.1007/s11886-020-01321-1.