PMID- 32571125 OWN - NLM STAT- MEDLINE DCOM- 20201102 LR - 20221207 IS - 1545-1550 (Electronic) IS - 1526-6028 (Linking) VI - 27 IP - 4 DP - 2020 Aug TI - Balloon Angioplasty of Infrapopliteal Arteries: A Systematic Review and Proposed Algorithm for Optimal Endovascular Therapy. PG - 547-564 LID - 10.1177/1526602820931488 [doi] AB - Endovascular revascularization has been increasingly utilized to treat patients with chronic limb-threatening ischemia (CLTI), particularly atherosclerotic disease in the infrapopliteal arteries. Lesions of the infrapopliteal arteries are the result of 2 different etiologies: medial calcification and intimal atheromatous plaque. Although several devices are available for endovascular treatment of infrapopliteal lesions, balloon angioplasty still comprises the mainstay of therapy due to a lack of purpose-built devices. The mechanism of balloon angioplasty consists of adventitial stretching, medial necrosis, and dissection or plaque fracture. In many cases, the diffuse nature of infrapopliteal disease and plaque complexity may lead to dissection, recoil, and early restenosis. Optimal balloon angioplasty requires careful attention to assessment of vessel calcification, appropriate vessel sizing, and the use of long balloons with prolonged inflation times, as outlined in a treatment algorithm based on this systematic review. Further development of specific devices for this arterial segment are warranted, including devices for preventing recoil (eg, dedicated atherectomy devices), treating dissections (eg, tacks, stents), and preventing neointimal hyperplasia (eg, novel drug delivery techniques and drug-eluting stents). Further understanding of infrapopliteal disease, along with the development of new technologies, will help optimize the durability of endovascular interventions and ultimately improve the limb-related outcomes of patients with CLTI. FAU - Giannopoulos, Stefanos AU - Giannopoulos S AUID- ORCID: 0000-0002-1942-911X AD - Division of Cardiology, Rocky Mountain Regional VA Medical Center, University of Colorado, Denver, CO, USA. FAU - Varcoe, Ramon L AU - Varcoe RL AUID- ORCID: 0000-0001-5611-6991 AD - Department of Surgery, Prince of Wales Hospital, Faculty of Medicine, University of New South Wales, The Vascular Institute, Prince of Wales Hospital, Sydney, New South Wales, Australia. FAU - Lichtenberg, Michael AU - Lichtenberg M AUID- ORCID: 0000-0003-2647-9876 AD - Angiology Department, Vascular Centre Clinic Arnsberg, Germany. FAU - Rundback, John AU - Rundback J AUID- ORCID: 0000-0002-8376-5644 AD - Advanced Interventional & Vascular Services LLP, Teaneck, NJ, USA. FAU - Brodmann, Marianne AU - Brodmann M AD - Division of Angiology, Department of Internal Medicine, Medical University of Graz, Austria. FAU - Zeller, Thomas AU - Zeller T AUID- ORCID: 0000-0003-2704-3871 AD - Department of Angiology, Universitats-Herzzentrum Bad Krozingen, Germany. FAU - Schneider, Peter A AU - Schneider PA AD - Division of Vascular and Endovascular Surgery, University of California at San Francisco, CA, USA. FAU - Armstrong, Ehrin J AU - Armstrong EJ AUID- ORCID: 0000-0002-1381-4754 AD - Division of Cardiology, Rocky Mountain Regional VA Medical Center, University of Colorado, Denver, CO, USA. LA - eng PT - Journal Article PT - Systematic Review DEP - 20200617 PL - United States TA - J Endovasc Ther JT - Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists JID - 100896915 SB - IM MH - *Algorithms MH - Amputation, Surgical MH - *Angioplasty, Balloon/adverse effects/instrumentation/mortality MH - Chronic Disease MH - Clinical Decision-Making MH - *Decision Support Techniques MH - Humans MH - Ischemia/diagnostic imaging/mortality/physiopathology/*therapy MH - Limb Salvage MH - Patient Selection MH - Peripheral Arterial Disease/diagnostic imaging/mortality/physiopathology/*therapy MH - *Popliteal Artery/diagnostic imaging/physiopathology MH - Recurrence MH - Risk Factors MH - Treatment Outcome MH - Vascular Patency OTO - NOTNLM OT - atherectomy OT - balloon angioplasty OT - calcification OT - chronic limb-threatening ischemia OT - critical limb ischemia OT - dissection OT - drug-coated balloon OT - drug-eluting stent OT - endovascular revascularization OT - infrapopliteal disease OT - recoil OT - residual stenosis OT - restenosis OT - stent EDAT- 2020/06/24 06:00 MHDA- 2020/11/03 06:00 CRDT- 2020/06/24 06:00 PHST- 2020/06/24 06:00 [pubmed] PHST- 2020/11/03 06:00 [medline] PHST- 2020/06/24 06:00 [entrez] AID - 10.1177/1526602820931488 [doi] PST - ppublish SO - J Endovasc Ther. 2020 Aug;27(4):547-564. doi: 10.1177/1526602820931488. Epub 2020 Jun 17.