PMID- 32578180 OWN - NLM STAT- MEDLINE DCOM- 20210414 LR - 20210414 IS - 1708-0428 (Electronic) IS - 0960-8923 (Linking) VI - 30 IP - 11 DP - 2020 Nov TI - Five-Year Outcomes of Laparoscopic Sleeve Gastrectomy in Japanese Patients with Class I Obesity. PG - 4366-4374 LID - 10.1007/s11695-020-04789-6 [doi] AB - BACKGROUND: Bariatric surgery is being recognized increasingly as an effective treatment for obesity and related comorbidities. In Japan, the cost of laparoscopic sleeve gastrectomy (LSG) is covered by the national health insurance for adults with a body mass index (BMI) >/= 35 kg/m(2) and specific comorbidities (type 2 diabetes mellitus (T2DM), hypertension (HT), dyslipidemia (DL), and obstructive sleep apnea syndrome (OSAS)). However, only 0.6% of the adult population have a BMI >/= 35 kg/m(2). In contrast, 4.3% have class I obesity (a BMI of 30-34.9 kg/m(2)). The BMI of Asians with central obesity-induced diabetes and other metabolic disorders is much lower than that of Westerners. OBJECTIVES: To evaluate the medium-term (up to 5 years) outcomes of LSG performed in Japanese patients with class I obesity. METHODS: One hundred eighteen consecutive patients with class I obesity treated by LSG at our center between August 2007 and December 2018 were included in a retrospective study. Mean preoperative body weight (BW) and BMI were 88.6 +/- 10.3 kg and 32.8 +/- 1.6 kg/m(2), respectively. Weight loss, comorbidity status, and adverse events were assessed. RESULTS: Mean BW/BMI at 1, 3, and 5 years after LSG decreased significantly to 66.6 +/- 11.2 kg/24.6 +/- 2.8 kg/m(2), 68.0 +/- 14.0 kg/25.4 +/- 4.0 kg/m(2), and 69.1 +/- 12.9 kg/26.5 +/- 3.0 kg/m(2), respectively. Mean total weight loss at 1, 3, and 5 years was 24.7 +/- 8.2%, 21.8 +/- 12.1%, and 18.5 +/- 9.7%, respectively. Metabolic disorders such as T2DM, HT, and DL improved significantly. There was no mortality. CONCLUSION: LSG is safe, yields excellent weight loss, and improves obesity-related comorbidities in Japanese patients with class I obesity. FAU - Seki, Yosuke AU - Seki Y AUID- ORCID: 0000-0002-3474-5671 AD - Weight loss and Metabolic Surgery Center, Yotsuya Medical Cube, 7-7 Nibancho, Chiyoda-ku, Tokyo, 102-0084, Japan. y-seki@mcube.jp. FAU - Kasama, Kazunori AU - Kasama K AD - Weight loss and Metabolic Surgery Center, Yotsuya Medical Cube, 7-7 Nibancho, Chiyoda-ku, Tokyo, 102-0084, Japan. FAU - Kikkawa, Eri AU - Kikkawa E AD - Weight loss and Metabolic Surgery Center, Yotsuya Medical Cube, 7-7 Nibancho, Chiyoda-ku, Tokyo, 102-0084, Japan. FAU - Yokoyama, Renzo AU - Yokoyama R AD - Weight loss and Metabolic Surgery Center, Yotsuya Medical Cube, 7-7 Nibancho, Chiyoda-ku, Tokyo, 102-0084, Japan. FAU - Nabekura, Taiki AU - Nabekura T AD - Weight loss and Metabolic Surgery Center, Yotsuya Medical Cube, 7-7 Nibancho, Chiyoda-ku, Tokyo, 102-0084, Japan. FAU - Sano, Akihiko AU - Sano A AD - Weight loss and Metabolic Surgery Center, Yotsuya Medical Cube, 7-7 Nibancho, Chiyoda-ku, Tokyo, 102-0084, Japan. FAU - Amiki, Manabu AU - Amiki M AD - Weight loss and Metabolic Surgery Center, Yotsuya Medical Cube, 7-7 Nibancho, Chiyoda-ku, Tokyo, 102-0084, Japan. AD - Department of Surgery, Kawasaki Saiwai Hospital, 31-27 Omiyacho, Saiwai-ku, Kawasaki-shi, Kanagawa, Japan. FAU - Kurokawa, Yoshimochi AU - Kurokawa Y AD - Department of Surgery, Yotsuya Medical Cube, 7-7 Nibancho, Chiyoda-ku, Tokyo, 102-0084, Japan. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Obes Surg JT - Obesity surgery JID - 9106714 SB - IM MH - Adult MH - Body Mass Index MH - *Diabetes Mellitus, Type 2/epidemiology/surgery MH - Gastrectomy MH - Humans MH - Japan/epidemiology MH - *Laparoscopy MH - Obesity/complications/surgery MH - *Obesity, Morbid/surgery MH - Retrospective Studies MH - Treatment Outcome OTO - NOTNLM OT - Class I obesity OT - Japanese OT - LSG OT - Mild obesity OT - Sleeve gastrectomy EDAT- 2020/06/25 06:00 MHDA- 2021/04/15 06:00 CRDT- 2020/06/25 06:00 PHST- 2020/06/25 06:00 [pubmed] PHST- 2021/04/15 06:00 [medline] PHST- 2020/06/25 06:00 [entrez] AID - 10.1007/s11695-020-04789-6 [pii] AID - 10.1007/s11695-020-04789-6 [doi] PST - ppublish SO - Obes Surg. 2020 Nov;30(11):4366-4374. doi: 10.1007/s11695-020-04789-6.