PMID- 3258284
OWN - NLM
STAT- MEDLINE
DCOM- 19880422
LR  - 20190908
IS  - 0340-0131 (Print)
IS  - 0340-0131 (Linking)
VI  - 60
IP  - 1
DP  - 1988
TI  - Evaluation of nicotine, cotinine, thiocyanate, carboxyhemoglobin, and expired 
      carbon monoxide as biochemical tobacco smoke uptake parameters.
PG  - 37-41
AB  - In a cross-sectional study on 236 individuals in Japan (174 males, 62 females; 
      149 smokers, 87 non-smokers) plasma nicotine (pnic), cotinine (pcot) and 
      thiocyanate (pSCN), urinary creatinine ratios of nicotine (unic), cotinine (ucot) 
      and thiocyanate (uSCN) as well as carboxyhemoglobin (COHb) and expired carbon 
      monoxide (COex) were determined. All tobacco smoke uptake parameters (TSUP) were 
      significantly elevated in smokers as compared to nonsmokers. The discriminant 
      power (smokers vs nonsmokers) rank in the following order: ucot approximately 
      pcot approximately unic greater than pSCN approximately COHb approximately pnic 
      greater than COex approximately uSCN. All parameters except for pnic are 
      significantly correlated with the self-reported number of cigarettes smoked per 
      day. The reason for the poor correlation of pnic with daily cigarette consumption 
      is the short half-life of pnic coupled with the arbitrary time of blood drawing 
      in relation to the last time of smoking.
FAU - Muranaka, H
AU  - Muranaka H
AD  - Kyoto Senbai Hospital, Japan.
FAU - Higashi, E
AU  - Higashi E
FAU - Itani, S
AU  - Itani S
FAU - Shimizu, Y
AU  - Shimizu Y
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Int Arch Occup Environ Health
JT  - International archives of occupational and environmental health
JID - 7512134
RN  - 0 (Thiocyanates)
RN  - 0 (Tobacco Smoke Pollution)
RN  - 6M3C89ZY6R (Nicotine)
RN  - 7U1EE4V452 (Carbon Monoxide)
RN  - 9061-29-4 (Carboxyhemoglobin)
RN  - AYI8EX34EU (Creatinine)
RN  - K5161X06LL (Cotinine)
RN  - O748SU14OM (thiocyanate)
SB  - IM
MH  - Adult
MH  - Breath Tests
MH  - Carbon Monoxide/metabolism
MH  - Carboxyhemoglobin/metabolism
MH  - Cotinine/metabolism
MH  - Creatinine/urine
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Nicotine/metabolism
MH  - Smoking/*metabolism
MH  - Thiocyanates/metabolism
MH  - *Tobacco Smoke Pollution
EDAT- 1988/01/01 00:00
MHDA- 1988/01/01 00:01
CRDT- 1988/01/01 00:00
PHST- 1988/01/01 00:00 [pubmed]
PHST- 1988/01/01 00:01 [medline]
PHST- 1988/01/01 00:00 [entrez]
AID - 10.1007/BF00409377 [doi]
PST - ppublish
SO  - Int Arch Occup Environ Health. 1988;60(1):37-41. doi: 10.1007/BF00409377.