PMID- 32594904
OWN - NLM
STAT- MEDLINE
DCOM- 20211125
LR  - 20220427
IS  - 1784-973X (Electronic)
IS  - 0001-5385 (Linking)
VI  - 76
IP  - 7
DP  - 2021 Sep
TI  - Characterisation of patients with and without cardiac magnetic resonance imaging 
      abnormalities presenting with myocardial infarction with non-obstructive coronary 
      arteries (MINOCA).
PG  - 760-768
LID - 10.1080/00015385.2020.1785134 [doi]
AB  - OBJECTIVE: The objective of the current study is to determine the characteristics 
      of myocardial infarction with non-obstructive coronary arteries (MINOCA) patients 
      with and without cardiac magnetic resonance (CMR) abnormalities. METHODS: We 
      evaluated patients admitted with a presentation of acute myocardial infarction 
      (MI) with no coronary obstruction on invasive angiography in our institution 
      between 2012 and 2017. Patients with prior cardiac disease, myocarditis, 
      Takotsubo cardiomyopathy and type 2 myocardial infarction were excluded. 
      Myocardial fibrosis was determined by late gadolinium enhancement (LGE). Patients 
      were divided into two groups based on the presence or absence of CMR 
      abnormalities (LGE or oedema). Major adverse cardiovascular events (MACE) were 
      defined as non-fatal MI, all-cause mortality, ventricular arrythmias or heart 
      failure hospitalisation at follow-up. RESULTS: Thirty-four patients fulfilling 
      the inclusion criteria were identified. Myocardial changes with CMR were observed 
      in 20 (59%) patients with signs of subendocardial infarct by LGE in 13 (38%) 
      patients, transmural infarct by LGE in 6 (18%) patients and one patient had 
      myocardial oedema. ECG and echocardiographic features were similar between 
      patients with and without CMR abnormalities. Troponin T was significantly higher 
      among patients with CMR abnormalities. The median duration of follow-up was 702 
      (IQR 456-1394) days. Two patients had MACE (both heart failure). One of them had 
      LGE changes. CONCLUSIONS: A significant number of patients with MINOCA have 
      ischaemic LGE changes or myocardial wall oedema. The patients with CMR 
      abnormalities have similar ECG and echocardiographic features except higher 
      biomarker, highlighting the role of CMR in patients with MINOCA.
FAU - Tayal, Bhupendar
AU  - Tayal B
AUID- ORCID: 0000-0002-6594-6177
AD  - Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
FAU - Freeman, Phillip
AU  - Freeman P
AD  - Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
FAU - Ericsson, Filip
AU  - Ericsson F
AD  - Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
FAU - Kragholm, Kristian Hay
AU  - Kragholm KH
AD  - Department of Internal Medicine, Region Hospital Nordjylland, Hjorring, Denmark.
FAU - Andersen, Niels Holmark
AU  - Andersen NH
AD  - Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
FAU - Hagendorff, Andreas
AU  - Hagendorff A
AD  - Department of Cardiology, University Hospital of Leipzig, Leipzig, Germany.
FAU - Aaroe, Jens
AU  - Aaroe J
AD  - Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
FAU - Sogaard, Peter
AU  - Sogaard P
AD  - Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
FAU - Zaremba, Tomas
AU  - Zaremba T
AD  - Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
LA  - eng
PT  - Journal Article
DEP - 20200629
PL  - England
TA  - Acta Cardiol
JT  - Acta cardiologica
JID - 0370570
RN  - 0 (Contrast Media)
RN  - AU0V1LM3JT (Gadolinium)
SB  - IM
MH  - Contrast Media
MH  - *Coronary Vessels/diagnostic imaging
MH  - Gadolinium
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Magnetic Resonance Imaging, Cine
MH  - *Myocardial Infarction/complications/diagnosis
MH  - Predictive Value of Tests
OTO - NOTNLM
OT  - Biomarkers
OT  - ECG
OT  - MINOCA
OT  - acute myocardial infarction
OT  - cardiac magnetic resonance
OT  - late gadolinium enhancement
EDAT- 2020/07/01 06:00
MHDA- 2021/11/26 06:00
CRDT- 2020/06/30 06:00
PHST- 2020/07/01 06:00 [pubmed]
PHST- 2021/11/26 06:00 [medline]
PHST- 2020/06/30 06:00 [entrez]
AID - 10.1080/00015385.2020.1785134 [doi]
PST - ppublish
SO  - Acta Cardiol. 2021 Sep;76(7):760-768. doi: 10.1080/00015385.2020.1785134. Epub 
      2020 Jun 29.