PMID- 32595403 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200928 IS - 1302-7123 (Print) IS - 1308-5123 (Electronic) IS - 1302-7123 (Linking) VI - 52 IP - 3 DP - 2018 TI - A Rare Tumor in Childhood Desmoplastic Infantile Astrocytoma: Two Case Reports. PG - 224-228 LID - 10.14744/SEMB.2018.29292 [doi] AB - Desmoplastic infantile astrocytomas (DIAs), are rare supratentorial tumors, usually observed in the first 24 months of life. Despite their aggressive appearance, they tend to follow a favorable clinical course. Total or near total resection of tumor is usually the treatment option. Desmoplastic Infantile Ganglioglioma (DIG) and DIA are WHO grade I tumors that have similar clinical and morphological findings. The only criterion in differential diagnosis is the neural component of DIG. These tumors both have dense fibroblastic stroma and positive staining with glial fibrillar acidic protein (GFAP) and CD34. A rare case of desmoplastic infantile astrocytoma presenting with right side partial seizures presented in a 1-year-old child. A rare case of desmoplastic infantile astrocytoma presenting with focal onset generalized seizures presented in a 1-year-old child. Despite their radiological and histological properties, these tumors have a benign course. After 3-year follow-up for the first case and 1-year follow-up for the second case, there was no recurrence. CI - Copyright: (c) 2018 by The Medical Bulletin of Sisli Etfal Hospital. FAU - Tanik, Canan AU - Tanik C AD - Department of Pathology, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey. FAU - Devecioglu, Elif Gokce AU - Devecioglu EG AD - Department of Pathology, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey. FAU - Hascicek, Seyhan AU - Hascicek S AD - Department of Pathology, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey. FAU - Meltem Can, Songul AU - Meltem Can S AD - Department of Neurology, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey. FAU - Halefoglu, Ahmet Mesrur AU - Halefoglu AM AD - Department of Radiology, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey. FAU - Kabukcuoglu, Fevziye AU - Kabukcuoglu F AD - Department of Pathology, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey. LA - eng PT - Case Reports DEP - 20180928 PL - Turkey TA - Sisli Etfal Hastan Tip Bul JT - Sisli Etfal Hastanesi tip bulteni JID - 9424130 PMC - PMC7315091 OTO - NOTNLM OT - Desmoplastic infantile astrocytoma OT - favorable prognosis OT - supratentorial COIS- Conflict of Interest: None declared. EDAT- 2018/09/28 00:00 MHDA- 2018/09/28 00:01 PMCR- 2018/09/28 CRDT- 2020/06/30 06:00 PHST- 2017/05/24 00:00 [received] PHST- 2018/02/12 00:00 [accepted] PHST- 2020/06/30 06:00 [entrez] PHST- 2018/09/28 00:00 [pubmed] PHST- 2018/09/28 00:01 [medline] PHST- 2018/09/28 00:00 [pmc-release] AID - MBSEH-52-224 [pii] AID - 10.14744/SEMB.2018.29292 [doi] PST - epublish SO - Sisli Etfal Hastan Tip Bul. 2018 Sep 28;52(3):224-228. doi: 10.14744/SEMB.2018.29292. eCollection 2018.