PMID- 32597279
OWN - NLM
STAT- MEDLINE
DCOM- 20210804
LR  - 20210804
IS  - 1369-1651 (Electronic)
IS  - 0899-0220 (Linking)
VI  - 37
IP  - 3
DP  - 2020 Sep
TI  - Secondary somatosensory area is involved in vibrotactile temporal-structure 
      processing: MEG analysis of slow cortical potential shifts in humans.
PG  - 222-232
LID - 10.1080/08990220.2020.1784127 [doi]
AB  - Purpose: Temporal-structure discrimination is an essential dimension of tactile 
      processing. Exploring object surface by touch generates vibrotactile input with 
      various temporal dynamics, which gives diversity to tactile percepts. Here, we 
      examined whether slow cortical potential shifts (SCPs) (<1 Hz) evoked by long 
      vibrotactile stimuli can reflect active temporal-structure processing.Materials 
      and methods: Vibrotactile-evoked magnetic brain responses were recorded in 10 
      right-handed healthy volunteers using a piezoelectric-based stimulator and 
      whole-head magnetoencephalography. A series of vibrotactile train stimuli with 
      various temporal structures were delivered to the right index finger. While all 
      trains consisted of identical number (15) of stimuli delivered within a fixed 
      duration (1500 ms), temporal structures were varied by modulating inter-stimulus 
      intervals (ISIs). Participants judged regularity/irregularity of ISI for each 
      train in the active condition, whereas they ignored the stimuli while performing 
      a visual distraction task in the passive condition. We analysed the 
      spatiotemporal features of SCPs and their behaviour using the minimum norm 
      estimates with the dynamic statistical parametric mapping.Results: SCPs were 
      localized to contralateral primary somatosensory area (S1), contralateral 
      superior temporal gyrus, and contralateral as well as ipsilateral secondary 
      somatosensory areas (S2). A significant enhancement of SCPs was observed in the 
      ipsilateral S2 (S2i) in the active condition, whereas such effects were absent in 
      the other regions. We also found a significant larger amplitude difference 
      between the regular- and irregular-stimulus evoked S2i responses during the 
      active condition than during the passive condition.Conclusions: This study 
      suggests that S2 subserves the temporal dimension of vibrotactile processing.
FAU - Hagiwara, Koichi
AU  - Hagiwara K
AUID- ORCID: 0000-0003-3006-5692
AD  - Department of Clinical Neurophysiology, Faculty of Medicine, Neurological 
      Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 
      Japan.
FAU - Ogata, Katsuya
AU  - Ogata K
AD  - Department of Clinical Neurophysiology, Faculty of Medicine, Neurological 
      Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 
      Japan.
FAU - Hironaga, Naruhito
AU  - Hironaga N
AD  - Department of Clinical Neurophysiology, Faculty of Medicine, Neurological 
      Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 
      Japan.
FAU - Tobimatsu, Shozo
AU  - Tobimatsu S
AD  - Department of Clinical Neurophysiology, Faculty of Medicine, Neurological 
      Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 
      Japan.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20200629
PL  - England
TA  - Somatosens Mot Res
JT  - Somatosensory & motor research
JID - 8904127
SB  - IM
MH  - Adult
MH  - Evoked Potentials, Somatosensory/*physiology
MH  - Female
MH  - Fingers/physiology
MH  - Humans
MH  - Magnetoencephalography
MH  - Male
MH  - Somatosensory Cortex/*physiology
MH  - Time Perception/*physiology
MH  - Touch Perception/*physiology
MH  - Vibration
MH  - Young Adult
OTO - NOTNLM
OT  - Secondary somatosensory area
OT  - slow cortical potential shifts (SCPs)
OT  - temporal perception
EDAT- 2020/07/01 06:00
MHDA- 2021/08/05 06:00
CRDT- 2020/06/30 06:00
PHST- 2020/07/01 06:00 [pubmed]
PHST- 2021/08/05 06:00 [medline]
PHST- 2020/06/30 06:00 [entrez]
AID - 10.1080/08990220.2020.1784127 [doi]
PST - ppublish
SO  - Somatosens Mot Res. 2020 Sep;37(3):222-232. doi: 10.1080/08990220.2020.1784127. 
      Epub 2020 Jun 29.