PMID- 32597392
OWN - NLM
STAT- MEDLINE
DCOM- 20201027
LR  - 20220531
IS  - 1969-6213 (Electronic)
IS  - 1774-024X (Linking)
VI  - 16
IP  - 8
DP  - 2020 Oct 23
TI  - Systematic use of intentional leaflet laceration to prevent TAVI-induced coronary 
      obstruction: feasibility and early clinical outcomes of the BASILICA technique.
PG  - 682-690
LID - EIJ-D-20-00386 [pii]
LID - 10.4244/EIJ-D-20-00386 [doi]
AB  - AIMS: The aim of this study was to evaluate the feasibility, efficacy and safety 
      of the bioprosthetic or native aortic scallop intentional laceration to prevent 
      iatrogenic coronary artery obstruction (BASILICA) technique during transcatheter 
      aortic valve implantation (TAVI) in an initial cohort at a single European 
      centre. METHODS AND RESULTS: Between August 2018 and March 2020, BASILICA was 
      attempted in 23 leaflets in 21 consecutive patients undergoing TAVI (age 78+/-6 
      years, 52% female). The index procedure was performed for 21 degenerated 
      bioprosthetic leaflets (90%, 9.2+/-2.6 years after implantation) and two native 
      leaflets (10%). BASILICA was performed for a single leaflet in 19 (90%) patients 
      and for both leaflets in two (10%) patients. The median total procedure time was 
      82 (interquartile range [IQR] 70-131) minutes, and BASILICA time (sheath-in to 
      laceration) was 45 (IQR 35-67) minutes. A cerebral embolic protection device was 
      used in 20 (95%) patients. BASILICA was feasible in all but one patient (95%) and 
      resulted in effective prevention of coronary obstruction in 19 patients (90%). 
      One patient developed a non-flow-limiting ostial lesion after BASILICA and TAVI, 
      and was treated by additional coronary stenting. No mortality or stroke was 
      observed up to 30 days. CONCLUSIONS: The feasibility, efficacy and safety of 
      BASILICA in this early single-centre experience were consistent with the initial 
      proof-of-concept reports. Further validation by ongoing multicentre registries 
      remains warranted.
FAU - Kitamura, Mitsunobu
AU  - Kitamura M
AD  - Department of Structural Heart Disease/Cardiology, Heart Center Leipzig at 
      University of Leipzig, Leipzig, Germany.
FAU - Majunke, Nicolas
AU  - Majunke N
FAU - Holzhey, David
AU  - Holzhey D
FAU - Desch, Steffen
AU  - Desch S
FAU - Bani Hani, Amjad
AU  - Bani Hani A
FAU - Krieghoff, Christian
AU  - Krieghoff C
FAU - Gutberlet, Matthias
AU  - Gutberlet M
FAU - Protsyk, Volodymyr
AU  - Protsyk V
FAU - Ender, Joerg
AU  - Ender J
FAU - Borger, Michael A
AU  - Borger MA
FAU - Dvir, Danny
AU  - Dvir D
FAU - Thiele, Holger
AU  - Thiele H
FAU - Abdel-Wahab, Mohamed
AU  - Abdel-Wahab M
LA  - eng
PT  - Journal Article
PL  - France
TA  - EuroIntervention
JT  - EuroIntervention : journal of EuroPCR in collaboration with the Working Group on 
      Interventional Cardiology of the European Society of Cardiology
JID - 101251040
SB  - IM
MH  - Aortic Valve/diagnostic imaging/surgery
MH  - *Aortic Valve Stenosis/prevention & control/surgery
MH  - *Coronary Occlusion
MH  - *Embolic Protection Devices
MH  - Feasibility Studies
MH  - Female
MH  - *Heart Valve Prosthesis
MH  - Humans
MH  - *Lacerations
MH  - Male
MH  - *Transcatheter Aortic Valve Replacement/methods
MH  - Treatment Outcome
EDAT- 2020/07/01 06:00
MHDA- 2020/10/28 06:00
CRDT- 2020/06/30 06:00
PHST- 2020/07/01 06:00 [pubmed]
PHST- 2020/10/28 06:00 [medline]
PHST- 2020/06/30 06:00 [entrez]
AID - EIJ-D-20-00386 [pii]
AID - 10.4244/EIJ-D-20-00386 [doi]
PST - ppublish
SO  - EuroIntervention. 2020 Oct 23;16(8):682-690. doi: 10.4244/EIJ-D-20-00386.