PMID- 32600493 OWN - NLM STAT- MEDLINE DCOM- 20220414 LR - 20220414 IS - 1469-8978 (Electronic) IS - 0033-2917 (Linking) VI - 52 IP - 4 DP - 2022 Mar TI - Empirically determined severity levels for binge-eating disorder outperform existing severity classification schemes. PG - 685-695 LID - 10.1017/S0033291720002287 [doi] AB - BACKGROUND: Eating-disorder severity indicators should theoretically index symptom intensity, impairment, and level of needed treatment. Two severity indicators for binge-eating disorder (BED) have been proposed (categories of binge-eating frequency and shape/weight overvaluation) but have mixed empirical support including modest clinical utility. This project uses structural equation model (SEM) trees - a form of exploratory data mining - to empirically determine the precise levels of binge-eating frequency and/or shape/weight overvaluation that most significantly differentiate BED severities. METHODS: Participants were 788 adults with BED enrolled in BED treatment studies. Participants completed interviews and self-report measures assessing eating-disorder and comorbid symptoms. SEM Tree analyses were performed by specifying an outcome model of BED severity and then recursively partitioning the outcome model into subgroups. Subgroups were split based on empirically determined values of binge-eating frequency and/or shape/weight overvaluation. SEM Forests also quantified which variable contributed more improvement in model fit. RESULTS: SEM Tree analyses yielded five subgroups, presented in ascending order of severity: overvaluation <1.25, overvaluation = 1.25-2.74, overvaluation = 2.75-4.24, overvaluation ⩾4.25 with weekly binge-eating frequency <4.875, and overvaluation ⩾4.25 with weekly binge-eating frequency ⩾4.875. SEM Forest analyses revealed that splits that occurred on shape/weight overvaluation resulted in much more improvement in model fit than splits that occurred on binge-eating frequency. CONCLUSIONS: Shape/weight overvaluation differentiated BED severity more strongly than binge-eating frequency. Findings indicate a nuanced potential BED severity indicator scheme, based on a combination of cognitive and behavioral eating-disorder symptoms. These results inform BED classification and may allow for the provision of more specific and need-matched treatment formulations. FAU - Forrest, Lauren N AU - Forrest LN AUID- ORCID: 0000-0003-1481-5078 AD - Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA. AD - Department of Psychology, Miami University, Oxford, OH, USA. FAU - Jacobucci, Ross C AU - Jacobucci RC AUID- ORCID: 0000-0001-7818-7424 AD - Department of Psychology, University of Notre Dame, Notre Dame, IN, USA. FAU - Grilo, Carlos M AU - Grilo CM AD - Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA. LA - eng GR - R01 DK049587/DK/NIDDK NIH HHS/United States GR - R01 DK114075/DK/NIDDK NIH HHS/United States GR - R01 DK112771/DK/NIDDK NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural DEP - 20200630 PL - England TA - Psychol Med JT - Psychological medicine JID - 1254142 SB - IM MH - Adult MH - *Binge-Eating Disorder/psychology MH - Body Image/psychology MH - Body Weight MH - Humans MH - Self Concept OTO - NOTNLM OT - Binge-eating disorder OT - SEM Trees OT - eating disorders OT - exploratory data mining OT - severity EDAT- 2020/07/01 06:00 MHDA- 2022/04/15 06:00 CRDT- 2020/07/01 06:00 PHST- 2020/07/01 06:00 [pubmed] PHST- 2022/04/15 06:00 [medline] PHST- 2020/07/01 06:00 [entrez] AID - S0033291720002287 [pii] AID - 10.1017/S0033291720002287 [doi] PST - ppublish SO - Psychol Med. 2022 Mar;52(4):685-695. doi: 10.1017/S0033291720002287. Epub 2020 Jun 30.