PMID- 32600865
OWN - NLM
STAT- MEDLINE
DCOM- 20210223
LR  - 20210223
IS  - 0929-6646 (Print)
IS  - 0929-6646 (Linking)
VI  - 120
IP  - 1 Pt 2
DP  - 2021 Jan
TI  - Clinical validation and utility of Chinese Eppendorf Itch Questionnaire in adults 
      with chronic pruritus symptoms.
PG  - 492-500
LID - S0929-6646(20)30282-5 [pii]
LID - 10.1016/j.jfma.2020.06.022 [doi]
AB  - BACKGROUND: Pruritus, or itch, is a prevalent symptom causing profound health 
      burden in many dermatological and non-dermatological disorders. Several itch 
      questionnaires have been created to assess itch. Particularly, Eppendorf Itch 
      Questionnaire (EIQ) is widely accepted since it encompasses various aspects of 
      itch, including intensity, affects, coping behavior, and motivation to scratch. 
      METHODS: In a cross-sectional survey, we examined the validity, reliability and 
      clinical utility of Traditional Chinese EIQ. RESULTS: We administered the 
      consensus version to 128 adults (median: 48.5 years, interquartile range [IQR]: 
      39-63) with active itch for more than 6 weeks at the Outpatient Clinics of three 
      medical centers in Taiwan. Clinical diagnoses included psoriasis (N = 82), 
      xerosis (N = 34), or other dermatitis (N = 12). Cronbach's alpha for each EIQ 
      scale ranged 0.82-0.98, suggesting good to excellent internal consistency and 
      reliability. Three EIQ scales significantly correlated with visual analogue scale 
      (VAS) for itch intensity (P </= 0.001 for median test), supporting for its 
      concurrent validity. None of EIQ scale was statistically correlated with 
      Psoriasis Area Severity Index (PASI) scores in psoriasis patients, confirming its 
      discriminant validity. Moreover, patients of different diagnoses had distinct 
      responses to the multi-scale EIQ index, affording it a better clinical test 
      (area-under-the-ROC curve [AUC]: 0.76, 95% CI: 0.63-0.90) than VAS alone (AUC: 
      0.42, 95%CI: 0.24-0.59) in distinguishing dermatitis/eczema-related itch from 
      psoriasis or xerosis-related itch. CONCLUSION: We demonstrated the reliability 
      and validity of Chinese EIQ in adult patients with chronic itch at the outpatient 
      setting. The study also revealed the diversified aspects of itch across patients 
      with various dermatoses.
CI  - Copyright (c) 2020 Formosan Medical Association. Published by Elsevier B.V. All 
      rights reserved.
FAU - Weng, Hao-Jui
AU  - Weng HJ
AD  - Department of Dermatology, Taipei Medical University- Shuang Ho Hospital, New 
      Taipei City, Taiwan; Department of Dermatology, School of Medicine, College of 
      Medicine, Taipei Medical University, Taipei, Taiwan; Department of Dermatology, 
      National Taiwan University Hospital, Taipei, Taiwan.
FAU - Shih, Ming-Hsiung
AU  - Shih MH
AD  - Department of Family Medicine, Far Eastern Memorial Hospital, New Taipei City, 
      Taiwan.
FAU - Tsai, Tsen-Fang
AU  - Tsai TF
AD  - Department of Dermatology, National Taiwan University Hospital, Taipei, Taiwan.
FAU - Song, Yi-Chun
AU  - Song YC
AD  - Department of Dermatology, National Taiwan University Hospital, Taipei, Taiwan.
FAU - Pan, Yi-Chin
AU  - Pan YC
AD  - Neurological Intensive Care Unit, Far Eastern Memorial Hospital, New Taipei City, 
      Taiwan.
FAU - Hu, Jia-Yu
AU  - Hu JY
AD  - Department of Nephrology, Far Eastern Memorial Hospital, New Taipei City, Taiwan.
FAU - Chung-Yee Hui, Rosaline
AU  - Chung-Yee Hui R
AD  - Department of Dermatology, Chang Gung Memorial Hospital, Taipei, Taiwan.
FAU - Lee, Wan-Ruoh
AU  - Lee WR
AD  - Department of Dermatology, Taipei Medical University- Shuang Ho Hospital, New 
      Taipei City, Taiwan; Department of Dermatology, School of Medicine, College of 
      Medicine, Taipei Medical University, Taipei, Taiwan; Graduate Institute of 
      Medical Sciences, Taipei Medical University, Taipei, Taiwan.
FAU - Huang, Yu-Huei
AU  - Huang YH
AD  - Department of Dermatology, Chang Gung Memorial Hospital, Taipei, Taiwan; College 
      of Medicine, Chang Gung University, Taoyuan, Taiwan. Electronic address: 
      huangyh@cgmh.org.tw.
FAU - Liu, Su-Hsun
AU  - Liu SH
AD  - International Health Program, National Yang Ming University, Taipei, Taiwan; 
      Health Management Center, Far Eastern Memorial Hospital, New Taipei City, Taiwan. 
      Electronic address: suhsun32@gmail.com.
LA  - eng
PT  - Journal Article
DEP - 20200627
PL  - Singapore
TA  - J Formos Med Assoc
JT  - Journal of the Formosan Medical Association = Taiwan yi zhi
JID - 9214933
SB  - IM
MH  - Adult
MH  - China
MH  - Cross-Sectional Studies
MH  - Humans
MH  - *Pruritus/diagnosis
MH  - *Quality of Life
MH  - Reproducibility of Results
MH  - Severity of Illness Index
MH  - Surveys and Questionnaires
MH  - Taiwan
OTO - NOTNLM
OT  - Pruritus
OT  - Surveys and questionnaires
OT  - Validation
COIS- Declaration of Competing Interest The authors declared no conflict of interest.
EDAT- 2020/07/01 06:00
MHDA- 2021/02/24 06:00
CRDT- 2020/07/01 06:00
PHST- 2020/05/01 00:00 [received]
PHST- 2020/06/02 00:00 [revised]
PHST- 2020/06/16 00:00 [accepted]
PHST- 2020/07/01 06:00 [pubmed]
PHST- 2021/02/24 06:00 [medline]
PHST- 2020/07/01 06:00 [entrez]
AID - S0929-6646(20)30282-5 [pii]
AID - 10.1016/j.jfma.2020.06.022 [doi]
PST - ppublish
SO  - J Formos Med Assoc. 2021 Jan;120(1 Pt 2):492-500. doi: 
      10.1016/j.jfma.2020.06.022. Epub 2020 Jun 27.