PMID- 32605626
OWN - NLM
STAT- MEDLINE
DCOM- 20201214
LR  - 20201214
IS  - 1757-7241 (Electronic)
IS  - 1757-7241 (Linking)
VI  - 28
IP  - 1
DP  - 2020 Jun 30
TI  - Resuscitative endovascular balloon occlusion of the aorta may contribute to 
      improved survival.
PG  - 62
LID - 10.1186/s13049-020-00757-2 [doi]
LID - 62
AB  - BACKGROUND: Resuscitative endovascular balloon occlusion of the aorta (REBOA) is 
      an increasingly used trauma resuscitation procedure, however, there are no 
      reports of whether or not the survival of patients treated with REBOA increases 
      over time. METHODS: This retrospective cohort study from a nationwide trauma 
      registry in Japan was conducted between 2004 and 2015. Patients treated with 
      REBOA were divided into three calendar year periods: early-period (2004-2007), 
      mid-period (2008-2011), and late-period (2012-2015). The primary outcome of 
      in-hospital survival was compared between the periods (early-period: reference) 
      using mixed effects logistic regression analysis after adjustment for 
      characteristics, trauma severity, and therapeutic choices. RESULTS: Of 236,698 
      trauma patients, 633 patients treated with REBOA were analyzed. Distribution of 
      the patients across periods was as follows: early-period (91), mid-period (276), 
      and late-period (266). In-hospital survival was 39, 49, and 60% in the 
      early-period, mid-period, and late-period, respectively. In regression modeling, 
      the late-period (OR = 2.976, 95% CI = 1.615-5.482) was associated with improved 
      in-hospital survival compared to the early-period, however, the mid-period 
      (OR = 1.614, 95% CI = 0.898-2.904) was not associated with improved survival. 
      CONCLUSIONS: Survival of patients treated with REBOA during the late-period 
      improved compared with survival during the early-period, after adjustment for 
      characteristics, trauma severity, and therapeutic choices. REBOA may be one of 
      the important factors related to progression of modern trauma treatment.
FAU - Aoki, Makoto
AU  - Aoki M
AUID- ORCID: 0000-0001-8239-8822
AD  - Department of Emergency Medicine, Gunma University Graduate School of Medicine, 
      Maebashi, Japan. aokimakoto@gunma-u.ac.jp.
FAU - Abe, Toshikazu
AU  - Abe T
AD  - Department of General Medicine, Juntendo University, Tokyo, Japan.
AD  - Health Services Research and Development Center, University of Tsukuba, Tsukuba, 
      Japan.
FAU - Hagiwara, Shuichi
AU  - Hagiwara S
AD  - Department of Emergency Medicine, National Hospital Organization Takasaki General 
      Medical Center, Takasaki, Japan.
FAU - Saitoh, Daizoh
AU  - Saitoh D
AD  - Department of Traumatology and Emergency Medicine, National Defense Medical 
      College, Tokorozawa, Japan.
FAU - Oshima, Kiyohiro
AU  - Oshima K
AD  - Department of Emergency Medicine, Gunma University Graduate School of Medicine, 
      Maebashi, Japan.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20200630
PL  - England
TA  - Scand J Trauma Resusc Emerg Med
JT  - Scandinavian journal of trauma, resuscitation and emergency medicine
JID - 101477511
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aorta, Thoracic/*surgery
MH  - Balloon Occlusion/*methods
MH  - Endovascular Procedures/*methods
MH  - Female
MH  - Humans
MH  - Japan/epidemiology
MH  - Male
MH  - Middle Aged
MH  - *Registries
MH  - Resuscitation/*methods
MH  - Retrospective Studies
MH  - Shock, Hemorrhagic/etiology/mortality/*therapy
MH  - Survival Rate/trends
MH  - Wounds and Injuries/complications/mortality/*surgery
PMC - PMC7325257
OTO - NOTNLM
OT  - Japan
OT  - Logistic models
OT  - Mortality trend
OT  - Resuscitative endovascular balloon occlusion of the aorta (REBOA)
OT  - Trauma
COIS- The authors declare that they have no competing interests.
EDAT- 2020/07/02 06:00
MHDA- 2020/12/15 06:00
PMCR- 2020/06/30
CRDT- 2020/07/02 06:00
PHST- 2019/11/14 00:00 [received]
PHST- 2020/06/24 00:00 [accepted]
PHST- 2020/07/02 06:00 [entrez]
PHST- 2020/07/02 06:00 [pubmed]
PHST- 2020/12/15 06:00 [medline]
PHST- 2020/06/30 00:00 [pmc-release]
AID - 10.1186/s13049-020-00757-2 [pii]
AID - 757 [pii]
AID - 10.1186/s13049-020-00757-2 [doi]
PST - epublish
SO  - Scand J Trauma Resusc Emerg Med. 2020 Jun 30;28(1):62. doi: 
      10.1186/s13049-020-00757-2.