PMID- 32606891
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220415
IS  - 1178-7074 (Print)
IS  - 1178-7074 (Electronic)
IS  - 1178-7074 (Linking)
VI  - 13
DP  - 2020
TI  - Predictors of ST Depression Resolution in STEMI Patients Undergoing Primary PCI 
      and Its Clinical Significance.
PG  - 271-279
LID - 10.2147/IJGM.S258573 [doi]
AB  - PURPOSE: ST depression resolution (STD-R) in ECG is a prognostic factor 
      indicative of successful fibrinolysis or angioplasty in the treatment of ST 
      elevation myocardial infarction (STEMI) and subsequent mortality. We conducted 
      this study to determine the clinical significance of STD-R and its predictors in 
      patients with anterior STEMI undergoing primary percutaneous intervention (PPCI). 
      METHODS: Admission documents of all patients with diagnosis of anterior STEMI who 
      were admitted to a specialty heart center and underwent PPCI since July 2018 
      until July 2019 were examined. The amount of ST elevation and depression in all 
      12 leads of a standard ECG at admission and 90 minutes after PPCI was measured 
      and resolution was determined. All patients were followed-up for 10.8+/-4.0 months. 
      RESULTS: A total of 179 patients had ST depression besides elevation in the first 
      ECG. Female gender, diabetes, not smoking, lower hemoglobin, and higher platelet 
      counts were significantly more common in the group with less than 50% resolution 
      of ST depression. STD-R <50% was significantly associated with the incidence of 
      in-hospital acute heart failure and major adverse cardiac events (MACE) (p value: 
      0.025 and 0.012, respectively) and resolution of ST elevation >/=50% was associated 
      with reduced in-hospital mortality (p value <0.0001). According to Kaplan-Meier 
      curve, survival in the two groups of STE-R >/=50% and STE-R <50% was significantly 
      different (Log rank: 31.18, p value<0.0001). CONCLUSION: STD-R can be considered 
      to have high predictive power, like STE-R for predicting incidence of in-hospital 
      acute heart failure and major adverse cardiac events.
CI  - (c) 2020 Ghaffari et al.
FAU - Ghaffari, Samad
AU  - Ghaffari S
AUID- ORCID: 0000-0001-6806-9387
AD  - Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, 
      Iran.
FAU - Kolahdouzan, Kasra
AU  - Kolahdouzan K
AUID- ORCID: 0000-0003-1522-5619
AD  - Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical 
      Sciences, Tehran, Iran.
FAU - Rahimi, Mehran
AU  - Rahimi M
AD  - Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, 
      Iran.
FAU - Tajlil, Arezou
AU  - Tajlil A
AD  - Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, 
      Iran.
LA  - eng
PT  - Journal Article
DEP - 20200608
PL  - New Zealand
TA  - Int J Gen Med
JT  - International journal of general medicine
JID - 101515487
PMC - PMC7292485
OTO - NOTNLM
OT  - ST depression resolution
OT  - ST elevation resolution
OT  - major adverse cardiac events
OT  - primary percutaneous intervention
COIS- The authors report no conflicts of interest in this work.
EDAT- 2020/07/02 06:00
MHDA- 2020/07/02 06:01
PMCR- 2020/06/08
CRDT- 2020/07/02 06:00
PHST- 2020/04/17 00:00 [received]
PHST- 2020/05/28 00:00 [accepted]
PHST- 2020/07/02 06:00 [entrez]
PHST- 2020/07/02 06:00 [pubmed]
PHST- 2020/07/02 06:01 [medline]
PHST- 2020/06/08 00:00 [pmc-release]
AID - 258573 [pii]
AID - 10.2147/IJGM.S258573 [doi]
PST - epublish
SO  - Int J Gen Med. 2020 Jun 8;13:271-279. doi: 10.2147/IJGM.S258573. eCollection 
      2020.