PMID- 3261122 OWN - NLM STAT- MEDLINE DCOM- 19880902 LR - 20190626 IS - 0002-8703 (Print) IS - 0002-8703 (Linking) VI - 116 IP - 2 Pt 1 DP - 1988 Aug TI - Surgical revascularization of left main coronary artery stenosis: determinants of perioperative and long-term outcome in the 1980s. PG - 440-6 AB - The postoperative courses of 176 patients who underwent coronary artery bypass surgery for significant left main coronary artery stenosis were analyzed to determine which preoperative clinical and angiographic factors correlated best with outcome. Clinical variables included age, sex, New York Heart Association (NYHA) anginal class, presence of unstable angina, and surgical class. The angiographic variables included percentage of left main stenosis, presence of right coronary artery stenosis, coronary dominance, number of vessels diseased, myocardial jeopardy score, and ejection fraction. The overall perioperative mortality rate was 9.1%. There was a significant increase in perioperative mortality among female patients (p less than 0.05) and patients undergoing emergency surgery (p less than 0.05). Patients with left main stenosis of 80% or more or with balanced or left dominant circulation showed trends toward increased perioperative mortality. Life-table analysis showed that emergency surgery and left main stenosis of 80% or more correlated with increased long-term mortality (p less than 0.05). No other variable tested showed a significant correlation with either perioperative or long-term mortality. A comparison of these results with studies performed in the 1970s shows that there has been considerable change in those factors which place a patient at increased risk for mortality during surgical treatment of left main coronary artery stenosis. FAU - Gomberg, J AU - Gomberg J AD - Philadelphia Heart Institute, Presbyterian-University of Pennsylvania Medical Center, Philadelphia 19104. FAU - Klein, L W AU - Klein LW FAU - Seelaus, P AU - Seelaus P FAU - Parr, G V AU - Parr GV FAU - Agarwal, J B AU - Agarwal JB FAU - Helfant, R H AU - Helfant RH LA - eng PT - Journal Article PL - United States TA - Am Heart J JT - American heart journal JID - 0370465 SB - IM MH - Aged MH - Coronary Angiography MH - *Coronary Artery Bypass/mortality MH - Coronary Disease/diagnostic imaging/mortality/*surgery MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Risk Factors EDAT- 1988/08/01 00:00 MHDA- 1988/08/01 00:01 CRDT- 1988/08/01 00:00 PHST- 1988/08/01 00:00 [pubmed] PHST- 1988/08/01 00:01 [medline] PHST- 1988/08/01 00:00 [entrez] AID - 0002-8703(88)90616-3 [pii] AID - 10.1016/0002-8703(88)90616-3 [doi] PST - ppublish SO - Am Heart J. 1988 Aug;116(2 Pt 1):440-6. doi: 10.1016/0002-8703(88)90616-3.